ICU Management & Practice, Volume 21 - Issue 1, 2021 Rethinking Critical Care - Use and Challenges of Artificial Intelligence Why digitalisation of intensive care medicine means less rather than more data Intensive Care Medicine is generating an amount of data that is hardly analysable by humans. Digitalising and using artificial intelligence has to focus on providing less rather than more data. Introduction - AI in Intensive Care Medicine: Ghost or G...

Original Investigation Caring for the Critically Ill PatientMarch 25, 2021 Effect of Helmet Noninvasive Ventilation vs High-Flow Nasal Oxygen on Days Free of Respiratory Support in Patients With COVID-19 and Moderate to Severe Hypoxemic Respiratory Failure: The HENIVOT Randomized Clinical Trial Domenico Luca Grieco, Luca S. Menga, Melania Cesarano, et al JAMA. Published online March 25, 2021. doi:10.1001/jama.2021.4682 Abstract Importance 背...

ICU Management & Practice, Volume 21 - Issue 1, 2021 How the Pandemic Changed Telemedicine An overview of the large-scale transition to telemedicine at Mayo Clinic during the COVID-19 pandemic and how it happened in a matter of days and represented one of the most rapid transformations of healthcare in history. Impact of the Pandemic on Society The 2019 Coronavirus Disease (COVID-19) pandemic has affected nearly all aspects of society, from family int...

ARTICLES| VOLUME 397, ISSUE 10283, P1447-1458, APRIL 17, 2021 Effect of infusion set replacement intervals on catheter-related bloodstream infections (RSVP): a randomised, controlled, equivalence (central venous access device)–non-inferiority (peripheral arterial catheter) trial Claire M Rickard, Nicole M Marsh, Emily N Larsen, et al Lancet 2021; 397: 1447-1458 DOI:https://doi.org/10.1016/S0140-6736(21)00351-2 Summary Background The opt...

ICU Management & Practice, Volume 21 - Issue 1, 2021 Prone Position in Awake, Non-Intubated Patients with ARDS: From Physiology to the Bedside Prone position (PP) in awake, non-intubated patients with respiratory failure is a physiology-based ventilatory strategy that improves oxygenation and may decrease the need for intubation and invasive mechanical ventilation (IMV). Introduction During the pandemic caused by the SARS-CoV-2 virus, which produces c...

Original Investigation Caring for the Critically Ill PatientMarch 23/30, 2021 Ventilator Weaning and Discontinuation Practices for Critically Ill Patients Karen E. A. Burns, Leena Rizvi, Deborah J. Cook, et al JAMA. 2021;325(12):1173-1184. doi:10.1001/jama.2021.2384 Abstract Importance 背景 Although most critically ill patients receive invasive mechanical ventilation (IMV), few studies have characterized ...

CDC Interim Guidelines for Fully Vaccinated People Efforts to end the COVID-19 pandemic finally became possible when, in December 2020, the FDA authorised the use of the first COVID-19 vaccine, manufactured by Pfizer-BioNTech. Soon after, two additional vaccines from Moderna and Johnson & Johnson also received emergency authorisation for use. As of 8 March 2021, over 31 million people in the U.S. have completed their vaccination.  As the number of ...

ORIGINAL ARTICLE Hypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial Rianne van Rijn, Ivo J. Schurink, Yvonne de Vries, et al N Engl J Med 2021; 384:1391-1401DOI: 10.1056/NEJMoa2031532 Abstract BACKGROUND Transplantation of livers obtained from donors after circulatory death is associated with an increased risk of nonanastomotic biliary strictures. Hypothermic oxygenated machine perfusion of livers may reduce the incidence of bili...

Original Investigation Caring for the Critically Ill PatientMarch 23/30, 2021 Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries Vincenzo Russotto, Sheila Nainan Myatra, John G. Laffey, et al JAMA. 2021;325(12):1164-1172. doi:10.1001/jama.2021.1727 Abstract Importance 背景 Tracheal intubation is one of the most commonly performed and high-risk intervention...

ICU Management & Practice, Volume 21 - Issue 1, 2021 Twenty Lessons from 2020: With a Focus on the ICU Perspective 2020 has been an unusual year. As we begin 2021, it is important for intensivists to look back over what has happened and see whether lessons can be learned from our combined experiences.The year 2020 has been unusual in so many ways and as we start a new year, it is interesting and important as intensivists to look back and reflect on what has...