GUIDELINES Published: 04 April 2023 ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia Ignacio Martin-Loeches, Antoni Torres, Blin Nagavci, et al Intensive Care Med (2023). https://doi.org/10.1007/s00134-023-07033-8 Question 1: In patients with sCAP, should rapid microbiological techniques be added to current testing of blood and respiratory tract samples? RecommendationsIf the technology is available, we&nb...

Guidelines Open Access Published: 01 March 2023 The European guideline on management of major bleeding and coagulopathy following trauma: sixth edition Rolf Rossaint, Arash Afshari, Bertil Bouillon, et al Crit Care 2023; 27: 80 I. Initial resuscitation and prevention of further bleeding Minimal elapsed time Recommendation 1 We recommend that severely injured patients be transported directly to an appropriate trauma facility (Grade 1B...

JAMA Clinical Guidelines Synopsis  February 16, 2023 Management of Thoracic Aortic Dissection Irbaz Hameed, Adam S. Cifu, Prashanth Vallabhajosyula JAMA. Published online February 16, 2023. doi:10.1001/jama.2023.0265 Guideline titles American Association for Thoracic Surgery Expert Consensus Document: Surgical Treatment of Acute Type A Aortic Dissection; Society of Thoracic Surgeons/American Association for Thoracic Surgery Clinical Prac...

Medical News in Brief  February 8, 2023 Updated COVID-19 Guidance for People Who Are Immunocompromised Emily Harris JAMA. Published online February 8, 2023. doi:10.1001/jama.2023.1176 In late January, the US Food and Drug Administration announced that Evusheld (the combined monoclonal antibodies tixagevimab and cilgavimab) is not currently authorized for emergency use because it’s likely ineffective against more than 90% o...

JAMA Clinical Guidelines Synopsis  September 15, 2022 Management of Heart Failure Mark N. Belkin, Adam S. Cifu, Sean Pinney JAMA. 2022;328(13):1346-1347. doi:10.1001/jama.2022.16667 Guideline title 2022 American College of Cardiology (ACC)/American Heart Association AHA)/Heart Failure Society of America (HFSA) Guidelines for the Management of Heart Failure Release date April 1, 2022 Prior versions 2017 ACC/AHA/HFSA Focused Update o...

JAMA Clinical Guidelines Synopsis  September 15, 2022 Management of Heart Failure Mark N. Belkin, Adam S. Cifu, Sean Pinney JAMA. Published online September 15, 2022. doi:10.1001/jama.2022.16667 Guideline title 2022 American College of Cardiology (ACC)/American Heart Association AHA)/Heart Failure Society of America (HFSA) Guidelines for the Management of Heart Failure Release date April 1, 2022 Prior versions 2017 ACC/AH...

JAMA Clinical Guidelines Synopsis  August 8, 2022 Treatment of Clostridioides difficile Infection Kanika Sehgal, Adam S. Cifu, Sahil Khanna JAMA. Published online August 8, 2022. doi:10.1001/jama.2022.12251 Guideline title ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections Release date May 18, 2021 Prior version 2013 Developer American College o...

US Preventive Services Task Force  Recommendation Statement August 23/30, 2022 Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement US Preventive Services Task Force JAMA. 2022;328(8):746-753. doi:10.1001/jama.2022.13044 Abstract Importance  Cardiovascular disease (CVD) is the leading cause of morbidity and death in the US and is the cause of more...

PULMONARY VASCULAR: GUIDELINES AND CONSENSUS STATEMENTS| VOLUME 162, ISSUE 1, P213-225, JULY 01, 2022 Thromboprophylaxis in Patients With COVID-19: A Brief Update to the CHEST Guideline and Expert Panel Report Lisa K. Moores, Tobias Tritschler, Shari Brosnahan, et al Chest 2022; 162: 213-225 Published:February 12, 2022 DOI:https://doi.org/10.1016/j.chest.2022.02.006 Background Patients hospitalized with COVID-19 often exhibit markers of a ...

Infectious Diseases Society of America Guidance on the Treatment of AmpC β-Lactamase–Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections Pranita D. Tamma, Samuel L. Aitken, Robert A. Bonomo, et al Clinical Infectious Diseases 2022; 74(12): 2089-2114 AMPC Β-LACTAMASE–PRODUCING ENTEROBACTERALES Question 1: Which Enterobacterales Should Be Considered at Moderate to High Risk for Clinically Signific...