JAMA Clinical Guidelines Synopsis  Management of Acute Coronary Syndrome Adam S. Vohra, Jason T. Alexander, Atman P. Shah JAMA Published Online: March 30, 2026 doi: 10.1001/jama.2026.1214 Guideline title ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndrome Release date February 27, 2025 Prior versions 2013 and 2014 Developers American College of Cardiology (ACC), American Heart Associati...

CONFERENCE REPORTS AND EXPERT PANEL Clinical criteria for the definition of refractory septic shock: a joint Delphi consensus from the Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) Leone, M., Myatra, S.N., Dugar, S. et al. Intensive Care Med (2026). https://doi.org/10.1007/s00134-026-08344-2 Abstract Objective A definition of refractory septic shock is necessary to guide diagnosis, management, prognostic...

JAMA Clinical Guidelines Synopsis  Caring for Pediatric Patients With Sepsis Tracy A. Lieu, Jason T. Alexander, Christopher W. Seymour JAMA Published Online: March 26, 2026 doi: 10.1001/jama.2026.3800 Guideline title Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 Release date March 23, 2026 Prior version 2020 Developer and funding source Society of Critical Care ...

JAMA Clinical Guidelines Synopsis  Caring for Adult Patients With Sepsis Christopher W. Seymour, Kirsten Bibbins-Domingo, Jason T. Alexander JAMA Published Online: March 26, 2026 doi: 10.1001/jama.2026.3793 Guideline title Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 Release date March 23, 2026 Developer European Society of Intensive Care Medicine (ESICM) and Society of Critical Care...

SPECIAL ARTICLE Society of Critical Care Medicine Guidelines on Caring for Older Adults in the ICU Ferrante, Lauren E.; Chaudhuri, Dipayan; Laiya Carayannopoulos, Kallirroi; et al Critical Care Medicine March 20, 2026 DOI: 10.1097/CCM.0000000000007085 Rationale:  Older adults (those 65 years old or greater) compose a substantial proportion of the ICU population. As older adults with critical illness possess unique factors and considerations relevant...

SPECIAL ARTICLE Society of Critical Care Medicine Guidelines for the Administration of Neuromuscular Blockade in Adults With Acute Respiratory Distress Syndrome Erstad, Brian L; Cobas, Miguel A; Qadir, Nida; et al Critical Care Medicine 54(3):p 634-643, March 2026. DOI: 10.1097/CCM.0000000000007002 Rationale:  Neuromuscular blocking agents (NMBAs) show potential benefits on mortality and other complications of acute respiratory distress syndrome (AR...

Practice Rapid Recommendations Summary of WHO clinical practice guidelines for influenza Per Olav Vandvik, Arnav Agarwal, Jamie Rylance, et al BMJ 2026; 392 doi: https://doi.org/10.1136/bmj-2025-087397 (Published 27 February 2026)Cite this as: BMJ 2026;392:e087397 Abstract About this guideline This BMJ Rapid Recommendation is a summary of a World Health Organization guideline published 12...

ESICM Recommendations for Management of Very Old Patients In ICU Wed, 29 Oct 2025 Very old patients, defined as those aged 80 years or older, represent the fastest-growing cohort in intensive care units across many countries. This population is characterised by high prevalence of functional impairments, multiple comorbidities, frailty, and marked biological and functional heterogeneity between individuals. The absence of robust evidence for managing cr...

FEATURE ARTICLE Determination of Adult Critical Care Physician Core Knowledge and Skills: Results of a Multidisciplinary, Modified Delphi Process Tisherman, Samuel A; Spevetz, Antoinette; Farmer, J. Christopher, et al Critical Care Medicine 54(2):p 224-233, February 2026. | DOI: 10.1097/CCM.0000000000006978 Abstract Objectives:  In the United States, training for physicians who manage critically ill adult patients (intensivists) evolved through para...

Update on ESICM Transfusion Guidelines In ICU Wed, 29 Oct 2025 At #LIVES2025, Nicole Juffermans, Professor of Translational Intensive Care Medicine at the University of Amsterdam Faculty of Medicine, provided an update on ESICM transfusion guidelines. While transition guidelines from 2020 and 2021 provided recommendations for transfusion practices, the perioperative setting has remained largely without updates. However, recent large trials have...