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Original Investigation Caring for the Critically Ill PatientMay 19, 2019 Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis Christopher W. Seymour, Jason N. Kennedy, Shu Wang, et al JAMA. Published online May 19, 2019. doi:10.1001/jama.2019.5791 Abstract 摘要 Importance 背景 Sepsis is a heterogeneous syndrome. Identification of distinct clinical phenotypes may allow more precise therapy and...
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Original Investigation Caring for the Critically Ill PatientMay 19, 2019 Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial Jean-Louis Vincent, Bruno Francois, Igor Zabolotskikh, et al JAMA. Published online May 19, 2019. doi:10.1001/jama.2019.5358 Abstract Importance 背景 Previous research suggested that soluble human recombinant thrombom...
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ARTICLES OF THE MONTH - APRIL 2019 ORIGINAL ~ Nasal high-flow preoxygenation for endotracheal intubation in the critically ill patient: a randomised clinical trial Guitton et al.: Nasal high-flow preoxygenation for endotracheal intubation in the critically ill patient: a randomised clinical trial This is the first randomised multicentre study comparing the use of HFNC with HFFM for the preoxygenation of non-severely hypoxemic patients in the ICU.  In thi...
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Original Investigation February 6, 2019 Association Between Emergency Medical Service Response Time and Motor Vehicle Crash Mortality in the United States James P. Byrne, N. Clay Mann, Mengtao Dai, et al JAMA Surg. 2019;154(4):286-293. doi:10.1001/jamasurg.2018.5097 Abstract Importance 背景 Motor vehicle crashes (MVCs) are a leading public health concern. Emergency medical service (EMS) response time is a modi...
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Comment & Response May 14, 2019 Acute Kidney Injury Related to Sepsis David S. Seres JAMA. 2019;321(18):1827-1828. doi:10.1001/jama.2019.2040 To the Editor 致编辑 Drs Legrand and Kellum reviewed the interpretation of serum creatinine in a critically ill patient.1 However, they only included a glancing reference to muscle mass and did not discuss protein intake. Both factors affect the evaluation of renal function and m...
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Original Investigation May 14, 2019 Effect of Restriction of the Number of Concurrently Open Records in an Electronic Health Record on Wrong-Patient Order Errors: A Randomized Clinical Trial Jason S. Adelman, Jo R. Applebaum, Clyde B. Schechter, et al JAMA. 2019;321(18):1780-1787. doi:10.1001/jama.2019.3698 Abstract Importance 背景 Recommendations in the United States suggest limiting the number of p...
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Original Investigation|Caring for the Critically Ill PatientMay 7, 2019 Effect of Trans-Nasal Evaporative Intra-arrest Cooling on Functional Neurologic Outcome in Out-of-Hospital Cardiac Arrest: The PRINCESS Randomized Clinical Trial Per Nordberg, Fabio Silvio Taccone, Anatolij Truhlar, et al JAMA. 2019;321(17):1677-1685. doi:10.1001/jama.2019.4149 Importance 背景 Therapeutic hypothermia may increase survival wit...
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JAMA Network Clinical Guideline Synopsis April 17, 2019 The Society of Vascular Surgery Practice Guidelines on the Care of Patients With Abdominal Aortic Aneurysms Michol A. Cooper, Gilbert R. Upchurch Jr JAMA Surg. Published online April 17, 2019. doi:10.1001/jamasurg.2019.0566 Guideline title: The Society for Vascular Surgery Practice Guidelines on the Care of Patients with an Abdominal Aortic Aneurysm 指南标题:血管外科学会腹主动脉瘤患者诊...
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#ISICEM19: Critical care medicine in space Dr. Matthieu Komorowski, Consultant in Intensive Care and Machine Learning researcher at Imperial College, London, talked about critical care in space at the 39th International Symposium on Intensive Care and Emergency Medicine.   One of the most distinct features about his talk (apart from the fact that it was about space), was that instead of presenting a lecture on space medicine, he narrated a story. The story is se...
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Original Investigation January 16, 2019 Association Between Postoperative Delirium and Long-term Cognitive Function After Major Nonemergent Surgery C. Adrian Austin, Thomas O’Gorman, Elizabeth Stern, et al JAMA Surg. 2019;154(4):328-334. doi:10.1001/jamasurg.2018.5093 Abstract Importance 背景 Postoperative delirium is associated with decreases in long-term cognitive function in elderly populations. 老年人术后谵妄伴随远期认知功能减退。 Objectiv...
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