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ORIGINAL ARTICLE Changes in Prevalence of Health Care–Associated Infections in U.S. Hospitals Shelley S. Magill, Erin O’Leary, Sarah J. Janelle, et al N Engl J Med 2018; 379:1732-1744 DOI: 10.1056/NEJMoa1801550 Abstract BACKGROUND 背景 A point-prevalence survey that was conducted in the United States in 2011 showed that 4% of hospitalized patients had a health care–associated infection. We repeated the survey in 2015 to assess changes in the prevalence of health care–assoc...
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Original Investigation Caring for the Critically Ill Patient October 24, 2018 Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients With Severe Traumatic Brain Injury: The POLAR Randomized Clinical Trial D. James Cooper, Alistair D. Nichol, Michael Bailey, et al JAMA. Published online October 24, 2018. doi:10.1001/jama.2018.17075 Abstract Importance 背景 After severe traumatic brain injury, induction of prophylactic hypothermia ...
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SCCM and ACEP Release Joint Statement About the SSC Hour-1 Bundle 摘自http://www.survivingsepsis.org/News/Pages/SCCM-and-ACEP-Release-Joint-Statement-About-the-Surviving-Sepsis-Campaign-Hour-1-Bundle.aspx The Society of Critical Care Medicine (SCCM) and the American College of Emergency Physicians (ACEP) acknowledge concerns expressed about the recently released Surviving Sepsis Campaign (SSC) Hour-1 Bundle and the appropriateness of implementation in the United Stat...
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Original Investigation Caring for the Critically Ill Patient October 24, 2018 Effect of Human Recombinant Alkaline Phosphatase on 7-Day Creatinine Clearance in Patients With Sepsis-Associated Acute Kidney Injury: A Randomized Clinical Trial Peter Pickkers, Ravindra L. Mehta, Patrick T. Murray, et al JAMA. Published online October 24, 2018. doi:10.1001/jama.2018.14283 Abstract Importance 背景 Sepsis-associated acute kidney injury (AKI) adversely affects long-term ...
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Original Investigation Caring for the Critically Ill Patient October 24, 2018 Effect of High-Flow Nasal Oxygen vs Standard Oxygen on 28-Day Mortality in Immunocompromised Patients With Acute Respiratory Failure: The HIGH Randomized Clinical Trial Elie Azoulay, Virginie Lemiale, Djamel Mokart, et al JAMA. Published online October 24, 2018. doi:10.1001/jama.2018.14282 Abstract Importance 背景 High-flow nasal oxygen therapy is increasingly used for acute hypoxemic r...
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Perspective > Medscape > Clinical Practice Guidelines Care of Adult Patients in the ICU Clinical Practice Guidelines (2018) Society of Critical Care Medicine Reviewed and summarized by Medscape editors October 04, 2018 Clinical practice guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU were released in September 2018 by the Society for Critical Care Medicine.[1] Pain Use ...
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Original Investigation Caring for the Critically Ill Patient October 24, 2018 Effect of a Low vs Intermediate Tidal Volume Strategy on Ventilator-Free Days in Intensive Care Unit Patients Without ARDS: A Randomized Clinical Trial Writing Group for the PReVENT Investigators JAMA. Published online October 24, 2018. doi:10.1001/jama.2018.14280 Abstract Importance 背景 It remains uncertain whether invasive ventilation should use low tidal volumes in critically ill pa...
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Managing patients with refractory septic shock The Surviving Sepsis Guidelines provide a specific framework to treat patients with septic shock. These guidelines include the use of antimicrobial therapy, source control, fluid therapy and targeted vasoporessors. However, there is still a small proportion of patients that does not respond to these measures and consequently deteriorates into refractory shock and progressive multi-organ failure. Specific guidelines to manage...
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INTENSIVE CARE MEDICINE ONLINE FIRST THIS WEEK Articles from RCTs released at LIVES 2018 Original ~ Impact of a multifaceted prevention programme on ventilator-associated pneumonia including selective oropharyngeal decontamination icTV interview with author Original ~ A multicentre randomised pilot trial on the effectiveness of different levels of cooling in comatose survivors of out-of-hospital cardiac arrest: the FROST-I trial  icTV interview with author Orig...
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Original Investigation September 2018 Characteristics and Outcomes of Surgical Patients With Solid Cancers Admitted to the Intensive Care Unit Kathryn Puxty, Philip McLoone, Tara Quasim, et al JAMA Surg. 2018;153(9):834-840. doi:10.1001/jamasurg.2018.1571 Abstract Importance 背景 Within the surgical population admitted to intensive care units (ICUs), cancer is a common condition. However, clinicians can be reluctant to admit patients with cancer to ICUs owing to conc...
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