JAMA Diagnostic Test Interpretation  August 21, 2023 Multistep Testing Algorithms for Clostridioides difficile Infection Maribeth R. Nicholson, Curtis J. Donskey JAMA. Published online August 21, 2023. doi:10.1001/jama.2023.15875 Case A10-year-old female with spina bifida and neurogenic bowel was hospitalized for abdominal pain, dehydration, and more than 20 episodes of watery diarrhea per day. Her symptoms be...

Teachable Moment  August 14, 2023 Mild Transaminase Elevation With Rapid Diagnostic Escalation: A Teachable Moment Priyal Gandhi, Niloofar Latifi JAMA Intern Med. Published online August 14, 2023. doi:10.1001/jamainternmed.2023.3884 Story From the Front Lines A33-year-old woman with well-controlled hypertension and body mass index of 21 (calculated as weight in kilograms divided by height in meters squared) presented to primary care for fo...

JAMA Diagnostic Test Interpretation  August 21, 2023 Multistep Testing Algorithms for Clostridioides difficile Infection Maribeth R. Nicholson, Curtis J. Donskey JAMA. Published online August 21, 2023. doi:10.1001/jama.2023.15875 Case A10-year-old female with spina bifida and neurogenic bowel was hospitalized for abdominal pain, dehydration, and more than 20 episodes of watery diarrhea per day. Her symptoms began 5 days after com...

Teachable Moment  Less Is More February 20, 2023 Safely Prescribing Nirmatrelvir and Ritonavir—Avoiding Drug-Drug Interactions Roshni Culas, Sridesh Nath, Sarath Nath JAMA Intern Med. 2023;183(4):362-363. doi:10.1001/jamainternmed.2022.6834 Story From the Front Lines A72-year-old man called his primary care physician (PCP) after 2 days of throat pain, myalgia, mild shortness of breath, and fever. A home COVID-19 antigen test result was positive. ...

Endgames Christmas 2022: Brain Stew Electrocardiogaffe Patricia McGettigan, Ian C Cooper, Jennifer H Martin, et al BMJ 2022; 379 doi: https://doi.org/10.1136/bmj-2022-074083 (Published 19 December 2022)Cite this as: BMJ 2022;379:e074083 Because a physician has possessed himself of an electrocardiograph, a polygraph, an x-ray machine, a blood pressure instrument, or some ingenious form of stethoscope, it does not at...

Endgames Christmas 2022: Brain Stew Electrocardiogaffe Patricia McGettigan, Ian C Cooper, Jennifer H Martin, et al BMJ 2022; 379 doi: https://doi.org/10.1136/bmj-2022-074083 (Published 19 December 2022)Cite this as: BMJ 2022;379:e074083 Because a physician has possessed himself of an electrocardiograph, a polygraph, an x-ray machine, a blood pressure instrument, or some ingenious form of stethoscope, it does not at all follow that he has become competent...

JAMA Diagnostic Test Interpretation  November 10, 2022 Peritoneal Fluid Analysis in Peritoneal Dialysis–Associated Peritonitis Jeffrey Perl, Ziv Harel, Sharon J. Nessim JAMA. Published online November 10, 2022. doi:10.1001/jama.2022.21289 Case A62-year-old woman undergoing peritoneal dialysis (PD) for kidney failure due to IgA nephropathy presented to the PD clinic with a 1-day history of severe abdominal pain...

JAMA Diagnostic Test Interpretation  November 10, 2022 Peritoneal Fluid Analysis in Peritoneal Dialysis–Associated Peritonitis Jeffrey Perl, Ziv Harel, Sharon J. Nessim JAMA. Published online November 10, 2022. doi:10.1001/jama.2022.21289 Case A62-year-old woman undergoing peritoneal dialysis (PD) for kidney failure due to IgA nephropathy presented to the PD clinic with a 1-day history of severe abdominal pain and cloudy PD fluid. Seven da...

JAMA Diagnostic Test Interpretation  August 8, 2022 Serum Cystatin C for Estimation of GFR Michael G. Shlipak, Lesley A. Inker, Josef Coresh JAMA. Published online August 8, 2022. doi:10.1001/jama.2022.12407 Case An 80-year-old man with type 2 diabetes and hypertension was referred to the nephrology clinic for assessment of persistent hyperkalemia despite discontinuation of his angiotensin-converting enzyme in...

JAMA Diagnostic Test Interpretation  August 8, 2022 Serum Cystatin C for Estimation of GFR Michael G. Shlipak, Lesley A. Inker, Josef Coresh JAMA. Published online August 8, 2022. doi:10.1001/jama.2022.12407 Case An 80-year-old man with type 2 diabetes and hypertension was referred to the nephrology clinic for assessment of persistent hyperkalemia despite discontinuation of his angiotensin-converting enzyme inhibitor. The patient was frail...