Teachable Moment  Less Is More February 20, 2023 Safely Prescribing Nirmatrelvir and Ritonavir—Avoiding Drug-Drug Interactions Roshni Culas, Sridesh Nath, Sarath Nath JAMA Intern Med. 2023;183(4):362-363. doi:10.1001/jamainternmed.2022.6834 Story From the Front Lines A72-year-old man called his primary care physician (PCP) after 2 days of throat pain, myalgia, mild shortness of breath, and fever. A home COVID-19 antigen test result was positive. ...

Endgames Christmas 2022: Brain Stew Electrocardiogaffe Patricia McGettigan, Ian C Cooper, Jennifer H Martin, et al BMJ 2022; 379 doi: https://doi.org/10.1136/bmj-2022-074083 (Published 19 December 2022)Cite this as: BMJ 2022;379:e074083 Because a physician has possessed himself of an electrocardiograph, a polygraph, an x-ray machine, a blood pressure instrument, or some ingenious form of stethoscope, it does not at...

Endgames Christmas 2022: Brain Stew Electrocardiogaffe Patricia McGettigan, Ian C Cooper, Jennifer H Martin, et al BMJ 2022; 379 doi: https://doi.org/10.1136/bmj-2022-074083 (Published 19 December 2022)Cite this as: BMJ 2022;379:e074083 Because a physician has possessed himself of an electrocardiograph, a polygraph, an x-ray machine, a blood pressure instrument, or some ingenious form of stethoscope, it does not at all follow that he has become competent...

JAMA Diagnostic Test Interpretation  November 10, 2022 Peritoneal Fluid Analysis in Peritoneal Dialysis–Associated Peritonitis Jeffrey Perl, Ziv Harel, Sharon J. Nessim JAMA. Published online November 10, 2022. doi:10.1001/jama.2022.21289 Case A62-year-old woman undergoing peritoneal dialysis (PD) for kidney failure due to IgA nephropathy presented to the PD clinic with a 1-day history of severe abdominal pain...

JAMA Diagnostic Test Interpretation  November 10, 2022 Peritoneal Fluid Analysis in Peritoneal Dialysis–Associated Peritonitis Jeffrey Perl, Ziv Harel, Sharon J. Nessim JAMA. Published online November 10, 2022. doi:10.1001/jama.2022.21289 Case A62-year-old woman undergoing peritoneal dialysis (PD) for kidney failure due to IgA nephropathy presented to the PD clinic with a 1-day history of severe abdominal pain and cloudy PD fluid. Seven da...

JAMA Diagnostic Test Interpretation  August 8, 2022 Serum Cystatin C for Estimation of GFR Michael G. Shlipak, Lesley A. Inker, Josef Coresh JAMA. Published online August 8, 2022. doi:10.1001/jama.2022.12407 Case An 80-year-old man with type 2 diabetes and hypertension was referred to the nephrology clinic for assessment of persistent hyperkalemia despite discontinuation of his angiotensin-converting enzyme in...

JAMA Diagnostic Test Interpretation  August 8, 2022 Serum Cystatin C for Estimation of GFR Michael G. Shlipak, Lesley A. Inker, Josef Coresh JAMA. Published online August 8, 2022. doi:10.1001/jama.2022.12407 Case An 80-year-old man with type 2 diabetes and hypertension was referred to the nephrology clinic for assessment of persistent hyperkalemia despite discontinuation of his angiotensin-converting enzyme inhibitor. The patient was frail...

JAMA Clinical Challenge March 21, 2022 Fever, Hypotension, and a Worsening Necrotic Wound Danielle M. Peterson, William E. Damsky, Matthew D. Vesely JAMA. Published online March 21, 2022. doi:10.1001/jama.2022.2806 Case On the day of giving birth via a normal vaginal delivery, a healthy woman in her 20s developed painful swelling on her right thigh, at the site of a methergine injection administered 1 day prior. Despite 3 days of treatment wi...

JAMA Clinical Challenge March 21, 2022 Fever, Hypotension, and a Worsening Necrotic Wound Danielle M. Peterson, William E. Damsky, Matthew D. Vesely JAMA. Published online March 21, 2022. doi:10.1001/jama.2022.2806 Case On the day of giving birth via a normal vaginal delivery, a healthy woman in her 20s developed painful swelling on her right thigh, at the site of a methergine injection administered 1 day prior. ...

JAMA Diagnostic Test Interpretation September 17, 2021 Interpreting SARS-CoV-2 Test Results KC Coffey, Daniel J. Diekema, Daniel J. Morgan, et al JAMA. Published online September 17, 2021. doi:10.1001/jama.2021.16146 Case A53-year-old woman was referred to the gastroenterology clinic for endoscopy because of a submucosal gastric nodule. She had not received a COVID-19 vaccination and lived in Maryland, which...