Invited Commentary  Aging and Health The Potential of Music as a Nonpharmacologic Intervention for the ICU—Sound Medicine Farah Acher Kaiksow, Eduard Eric Vasilevskis JAMA Intern Med Published Online: October 13, 2025 doi: 10.1001/jamainternmed.2025.5260 The intensive care unit (ICU) offers lifesaving interventions, but it is also associated with considerable patient pain, anxiety, and high rates of delirium. Delirium in patients in the ICU is a hig...

Original Investigation  AI in Medicine Individualized Prediction of Platelet Transfusion Outcomes in Preterm Infants With Severe Thrombocytopenia Hilde van der Staaij, Ilaria Prosepe, Camila Caram-Deelder, et al JAMA 2025;334;(14):1267-1277. doi:10.1001/jama.2025.14194 Key Points Question  When and in which preterm infants with severe thrombocytopenia do platelet transfusions reduce the risk of major bleeding or death? Findings &nb...

Quality of Life and Functional Recovery After Intensive Care for Sepsis In Sepsis Tue, 15 Jul 2025 Many ICU survivors of sepsis do not fully regain health or normal function, facing issues in cognition, physical, and mental health (post-sepsis syndrome). Recovery, not just survival, is crucial to patients and families, but studies show increased healthcare use post-ICU, indicating incomplete recovery. Health, per WHO, includes physical, mental, an...

Research Letter  Social Media Use Trajectories and Cognitive Performance in Adolescents Jason M. Nagata, Jennifer H. Wong, Kristen E. Kim, et al JAMA Published Online: October 13, 2025 doi: 10.1001/jama.2025.16613 Social media is an increasingly important aspect of early adolescent lives, and trajectories of use have been correlated with negative psychosocial outcomes.1,2 Studies of the link between total screen time and cognitive performance in those ...

Two cases of Middle East respiratory syndrome (MERS) in travellers returning to France from the Arabian Peninsula Epidemiological update 5 Dec 2025 On 3 December 2025, the French Ministry of Health reported two imported human Middle East respiratory syndrome (MERS) cases with travel history to the Arabian Peninsula. The two affected individuals participated in the same group trip. No secondary cases have been identified so far. French authorities are implement...

Editorials Gaza: documenting the trauma of war Derek Summerfield BMJ 2025; 390 doi: https://doi.org/10.1136/bmj.r2012 (Published 25 September 2025)Cite this as: BMJ 2025;390:r2012 Collated descriptions of injuries illustrate the daunting challenges ahead Little is known about patterns of injury in civilians subjected to high intensity bombardments, such as those that occurred during the US and UK invasions of Iraq and Afghanistan and which are now occurring...

Original Investigation  Health Informatics Use of an AI Scribe and Electronic Health Record Efficiency Kevin Pearlman, Wen Wan, Sachin Shah, et al JAMA Netw Open 2025;8;(10):e2537000. doi:10.1001/jamanetworkopen.2025.37000 Key Points Question  Is an ambulatory clinician’s use of an artificial intelligence (AI) scribe associated with improved efficiency in the electronic health record (EHR) when compared w...

Smarter Triage with AI in Emergency Departments  In ICU Sun, 6 Jul 2025 Emergency departments (EDs) are often the first point of contact for patients in acute distress, yet they remain among the most overburdened areas in healthcare. Overcrowding, long wait times and clinician burnout are endemic challenges that compromise patient outcomes and staff morale. With artificial intelligence technologies gaining traction across clinical settings, UMass ...

Original Investigation  Critical Care Medicine One-Year Outcomes After Traumatic Brain Injury and Early Extracranial Surgery in the TRACK-TBI Study Christopher J. Roberts, Amelia W. Maiga, Jason Barber, et al JAMA Netw Open 2025;8;(10):e2537271. doi:10.1001/jamanetworkopen.2025.37271 Key Points Question  Are traumatic brain injury (TBI) outcomes at 1 year worse in individuals exposed to extracranial surge...

Editorial  Perioperative Outcomes—The Limits of Blood Pressure–Centered Strategies Matthieu Legrand, François Lamontagne, Romain Pirracchio JAMA Published Online: October 12, 2025 doi: 10.1001/jama.2025.18572 Intraoperative hypotension is very common, affecting 30% to 80% of surgical patients.1-3 Results of observational studies suggest that even brief episodes of intraoperative hypotension are associated with an increased risk of postoperative complic...