What Drives ICU Staff to Act on Sustainability  In ICU Mon, 10 Nov 2025 Environmental sustainability is an increasingly visible challenge in intensive care, where resource-intensive care processes intersect with rising expectations for greener practice. Evidence from a multi-centre survey across nine French hospitals offers a detailed view of how intensive care unit (ICU) healthcare workers (HCWs) approach this agenda, how much time they are willi...

Invited Commentary  Trauma Patient Volume and Clinician Outcomes—Practice Makes Perfect? Kenji Inaba, Nichole Bosson JAMA Surg Published Online: February 18, 2026 doi: 10.1001/jamasurg.2025.6752 Regionalization is a standard across many industries, with well-defined benefits in terms of resource aggregation, improved efficiency, and downstream cost savings. By concentrating expertise and experience, it also stands to reason that, for the care of the in...

Research Effectiveness of drug interventions to prevent delirium after surgery for older adults: systematic review and network meta-analysis of randomised controlled trials Matthew Luney, Luke Holdsworth, Arwa Hanaga, et al BMJ 2026; 392 doi: https://doi.org/10.1136/bmj-2025-085539 (Published 12 February 2026)Cite this as: BMJ 2026;392:e085539 Abstract Objective To identify which drugs are effective at preventing...

International Severity of Illness Scoring System In ICU Wed, 26 Nov 2025 Developing a globally applicable critical care severity score is an urgent priority for improving research, benchmarking, quality improvement, and public health response across diverse health systems. Severity scores have long been central to ICU practice, supporting benchmarking, risk adjustment, resource allocation, and disease characterisation. Yet, most existing scores were de...

Articles Survival effect of prehospital emergency anaesthesia with intubation in risk-stratified patients with major trauma: a causal modelling study Amy PK Nelson, Nick Dodds, Mohamad Zeina, et al Lancet Respir Med Available online 11 February 2026 https://doi.org/10.1016/S2213-2600(25)00370-4 Summary Background Trauma is among the top 10 most common causes of disability worldwide, accounting for more than 100 million disability-adjusted life-years (...

Original Investigation  Surgery Antibiotic Prophylaxis Strategies and Surgical Site Infections in Colorectal Surgery: A Systematic Review and Network Meta-Analysis Shahrzad Motaghi, Samer G. Karam, Francesca Mulazzani, et al JAMA Netw Open 2026;9;(2):e2560095. doi:10.1001/jamanetworkopen.2025.60095 Key Points Question  Which antibiotic prophylaxis regimens are associated with the lowest risk of surgical s...

Editorial  Evaluating Cryopreserved and Liquid-Stored Platelets for Bleeding During Cardiac Surgery Timothy A. Pritt JAMA Surg Published Online: February 18, 2026 doi: 10.1001/jamasurg.2025.6723 There is no substitute for blood during the treatment of hemorrhage. From the first reported successful transfusion of human blood to treat postpartum hemorrhage in 1825,1 to the early use of whole blood in combat casualty care during World War I,2 an...

Guideline-Driven LLM Boosts Sepsis Mortality Prediction  In Sepsis Tue, 2 Dec 2025 Sepsis remains a major cause of in-hospital mortality worldwide and places a substantial burden on intensive care units and healthcare systems. Despite regular updates to clinical guidance and advances in treatment, outcomes for many patients remain poor and early identification of those at highest risk continues to be challenging. Conventional risk scores and tradi...

Original Investigation  Statistics and Research Methods Design and Implementation of Observational Studies Emulating a Target Trial Yan Ren, Yulong Jia, Lingyan Liu, et al JAMA Netw Open 2026;9;(2):e2558262. doi:10.1001/jamanetworkopen.2025.58262 Key Points Question  In which clinical scenarios has target trial emulation (TTE) been applied, and how well do TTE studies adhere to key principles of target tr...

Invited Commentary  Anesthesiology Antibiotic Selection and Redosing to Prevent Surgical Site Infections—When Timing Is Not Enough Nicole A. Wilson JAMA Netw Open 2026;9;(2):e2559356. doi:10.1001/jamanetworkopen.2025.59356 Surgical site infections (SSIs) remain among the most common and costly complications following surgery, despite decades of quality improvement efforts. In this context, the multicenter cohort study by Bardia et al1 provides timely a...