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Methemoglobinemia Due to Antifreeze Ingestion Andrew N. Farkas, Anthony Scoccimarro, Anthony F. Pizon N Engl J Med 2017; 377: 1993-1994 To the Editor: Ingestion of antifreeze that contains ethylene glycol produces acidosis, nephropathy, coma, and cardiovascular collapse.1 Previously, minimal increases in methemoglobin levels (to as high as 6%; normal value, < 1.0% or < 1.5%, depending on the assay) after ingestion of antifreeze have been reported,2 with no known caus...
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Images in Clinical Medicine Falciform Ligament Sign Po-Chen Chou, Yu-Jang Su N Engl J Med 2017; 377: e28 DOI:10.1056/NEJMicm1613914 An 87-year-old woman with a history of hypertension and peptic ulcer disease presented to the emergency department with a 3-day history of abdominal distention, pain in the epigastrium, and watery diarrhea. She had hypotension (blood pressure of 78/49 mm Hg), and diffuse abdominal tenderness with guarding was observed on physical examination. ...
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12 Causes of Discolored Urine Christopher S Atalla, DO; Josh Palka, DO | November 15, 2017 Adapted images courtesy of Regensburger M, Huttner HB, Doerfler A, Schwab S, Staykov D. Springerplus. 2014;3:551. [Open access.] PMID: 25332856, PMCID: PMC4192142. Normal urine coloration ranges from clear to yellow. However, a multitude of pathologies and agents can change the color and/or clarity of urine. This slideshow discusses several potential causes of abnormal urine color. ...
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Images in Clinical Medicine Decompression Sickness N Engl J Med 2017; 377: 1568 Qing Sun, Guangkai Gao DOI:10.1056/NEJMicm1615505 A  42-year-old man presented to the emergency department with palpitations, arthralgias, and vomiting 2 hours after scuba diving to a depth of 26 m. The physical examination revealed diffuse violaceous skin mottling over his trunk and arms (Panel A). Laboratory values were notable for mild elevations in levels of serum aminotransferases, creati...
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IMAGES IN CLINICAL MEDICINE Compartment Syndrome Aileen F. Egan, M.B., B.A.O., M.Ch., and Kevin C. Cahill, M.D. N Engl J Med 2017; 377:1877 November 9, 2017 DOI: 10.1056/NEJMicm1701729 A 26-year-old man presented to the emergency department with a painful, swollen left hand (Panel A). He had been lying on the ground for more than 13 hours after using illicit drugs. The physical examination revealed edema in the left hand and forearm. Active and passive motion of the hand ...
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Images in Clinical Medicine Takotsubo Cardiomyopathy Abhishek Maiti, Abhijeet Dhoble N Engl J Med 2017; 377: e24 DOI:10.1056/NEJMicm1615835 A  61-year-old woman with hypertension and hypothyroidism presented to the emergency department with acute onset of severe chest pain. She reported multiple recent stressors, including the death of her dog. An electrocardiogram showed ST-segment elevation in the anterolateral leads. Emergency coronary angiography revealed normal coron...
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Tension Pneumoperitoneum Associated with Nasopharyngeal Catheter Oxygen Delivery during Bronchoscopy Karim El-Kersh, Hala Karnib Am J Respir Crit Care Med 2017 Published on 29-June-2017 as 10.1164/rccm.201701-0181IM A 61-year-old female with chronic lymphocytic leukemia was undergoing bronchoscopy with bronchoalveolar lavage. The patient never smoked and she did not have any underlying chronic gastric disease. The bronchoscopy was performed in supine position under conscio...
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Images in Clinical Medicine Calcium Oxalate Crystals in Ethylene Glycol Toxicity Mohamad Hanouneh, Teresa K. Chen N Engl J Med 2017; 377: 1467 An 80-year-old man with a remote history of alcohol-use disorder presented to the emergency department with altered mental status after a fall at home. He was somnolent and unable to provide any further history. Serum studies revealed a creatinine level of 2.4 mg per deciliter (212 μmol per liter; reference range, 0....
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JAMA Diagnostic Test Interpretation September 26, 2017 Aspergillus Galactomannan for Diagnosing Invasive Aspergillosis Marisa H. Miceli, Carol A. Kauffman JAMA. 2017;318(12):1175-1176. doi:10.1001/jama.2017.10661 A 67-year-old man with granulomatous polyangiitis (Wegener granulomatosis) complicated by end-stage renal disease requiring hemodialysis and mild pulmonary fibrosis, was hospitalized with a 2-week history of worsening dyspnea and dry cough. He was taking ...
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Viewpoint October 3, 2017 Research Integrity, Academic Promotion, and Attribution of Authorship and Nonauthor Contributions Spyros D. Mentzelopoulos, Spyros G. Zakynthinos JAMA. 2017;318(13):1221-1222. doi:10.1001/jama.2017.11790 Guidelines for the academic promotion of university faculty members are essential for the achievement and maintenance of high academic quality. However, these guidelines and criteria vary widely around the world and in the United States, with ...
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