Update: Guidelines on Adult Critical Care Ultrasonography In ICU Tue, 4 Mar 2025 Critical care ultrasonography (CCUS) is a point-of-care tool used by clinicians to aid diagnosis, manage care, and guide procedures for critically ill patients. It has become widely adopted in critical care, but its impact on patient outcomes remains uncertain. This executive summary updates previous CCUS guidelines by comparing clinical outcomes with and without CCUS i...

Invited Commentary  Pediatrics April 11, 2025 Vasoactive Selection for Pediatric Septic Shock—Where to Begin? Scott L. Weiss JAMA Netw Open. 2025;8(4):e254726. doi:10.1001/jamanetworkopen.2025.4726 Vasoactive medications are commonly used to reverse cardiovascular dysfunction and optimize tissue perfusion in children with fluid-refractory or fluid-averse septic shock. The 2020 Surviving Sepsis Campaign International Guidelines for the Mana...

Variability in Interprofessional ICU Staffing In ICU Tue, 4 Mar 2025 ICU staffing varies widely due to factors like physician work-hour limitations, increased use of advanced practice providers (NPs and PAs), telemedicine, and shortages of healthcare workers, including nurses and ICU physicians. There is limited and low-quality data to guide staffing decisions, with most research focusing on individual roles rather than the interprofessional teams that...

The Future of Extracorporeal Care In ICU Tue, 4 Mar 2025 The incidence of long COVID is estimated to be between 6% and 40%. This highlights the need for ongoing care beyond initial survival. However, healthcare often focuses on survival as a binary outcome rather than considering the long-term recovery process, which can range from full recovery to ongoing dependence on institutional care and rehabilitation. There is an increasing need to address the c...

Invited Commentary  Cardiology April 2, 2025 What’s Missing From Value-Based Care—Accounting for the Costs and Benefits of Quality Improvement Donald E. Casey Jr JAMA Netw Open. 2025;8(4):e252510. doi:10.1001/jamanetworkopen.2025.2510 Current estimated direct and indirect economic cost of cardiovascular diseases from 2019 to 2020 was $422.3 billion with coronary heart disease (CHD) accounting for more than 40% of deaths attributable to dis...

Impact of Postoperative Sepsis on Dementia In Sepsis Mon, 10 Feb 2025 Dementia is a progressive neurodegenerative disease with growing public health and economic implications. In 2019, 57.4 million people had dementia worldwide, a number projected to reach 152.8 million by 2050. The global financial burden is substantial, estimated at $1.31 trillion annually. As dementia prevalence rises, increased healthcare resources and preventive strategies will be...

Editorial  March 31, 2025 Mitigating the Impact of Retracted Studies in the Medical Literature Cary P. Gross, Annette Flanagin, Eli N. Perencevich, et al JAMA Intern Med. Published online March 31, 2025. doi:10.1001/jamainternmed.2025.0251 Medical publishing, and the scientific research ecosystem in general, face substantial challenges. Some are external, ranging from a relative decrease in research funding, to i...

Extracorporeal Blood Purification in Critically Ill Paediatric Patients In ICU Mon, 10 Feb 2025 Extracorporeal blood purification therapies (EBPTs) use extracorporeal circuits to remove or modulate circulating substances for organ support and detoxification. These therapies include renal replacement therapy, ultrafiltration, haemoadsorption, and plasma therapies. Recent advances in technology have expanded EBPTs from single-organ to multiple-organ supp...

Editorial  March 30, 2025 Risk of Running—A Contemporary Look at Cardiac Arrest in Long-Distance Races Nimesh S. Patel, Mark S. Link JAMA. Published online March 30, 2025. doi:10.1001/jama.2025.3646 Millions of people participate in long-distance running, particularly marathons and half-marathons, annually.1While the health benefits of regular exercise are well established,2 long-distance running can cause significant cardiovascular stre...

Liberal vs Restrictive Transfusion Strategies in Subarachnoid Haemorrhage In ICU Mon, 10 Feb 2025 Spontaneous aneurysmal subarachnoid haemorrhage (SAH) is a serious cerebrovascular event contributing significantly to morbidity and mortality. It is often associated with anaemia, which can worsen brain injury through cerebral hypoxia, particularly when haemoglobin (Hb) levels drop below 5 g/dL.  In healthy brains, anaemia is compensated by increa...