Invited Commentary  Nephrology AI-Enabled Acute Kidney Injury Prediction and the Challenge of Prevention Charat Thongprayoon, Francesco Pesce, Wisit Cheungpasitporn JAMA Netw Open 2026;9;(7):e2622565. doi:10.1001/jamanetworkopen.2026.22565 Acute kidney injury (AKI) remains one of the most common, serious, and consequential complications of hospitalization. It is associated with longer hospital stays, higher costs, greater short-term and long-term morta...

Multidisciplinary Telemedicine Intervention for ICU Recovery In ICU Tue, 7 Jul 2026 A randomised controlled trial evaluated the feasibility of delivering a multidisciplinary telemedicine ICU recovery clinic for survivors of critical illness and of collecting long-term recovery outcomes. Survivors of sepsis and acute respiratory distress syndrome (ARDS) frequently develop post-intensive care syndrome (PICS), which encompasses persistent cognitive, psych...

Editorial  Trials Terminated Early: When Is Enough, Enough? Alison J. Huang, Roger J. Lewis JAMA Published Online: August 5, 2026 doi: 10.1001/jama.2026.8878 What does it mean to stop a clinical trial early? In the early days of the modern randomized trial, it meant the research had not gone according to plan.1 Trialists were expected to adhere to the sample sizes they originally proposed based on early assumptions about underlying event rates, loss to...

Chest Infections: Original Research Clinical Sampling Challenges in Diagnosing Severe Respiratory Viral Infections Antonio Piralla, Cristina Russo, Stefania Ranno, et al Chest 2026; 170: 41-53 https://doi.org/10.1016/j.chest.2025.12.056 Background Respiratory viruses are a primary cause of pneumonia in both children and adults, particularly in cases of severe acute respiratory infection (SARI) requiring hospitalization. Although molecular diagnostic tech...

Invited Commentary  Anesthesiology A New Trial to Better Define the Role of Video Laryngoscopes Luc Desmedt, Jean-Baptiste Lascarro JAMA Netw Open 2026;9;(8):e2625982. doi:10.1001/jamanetworkopen.2026.25982 Endotracheal intubation is among the most frequently performed high-stakes procedures in anesthesiology. In the operating room (OR), it is usually planned, controlled, and uneventful; outside the OR, it may occur in critically ill patients with litt...

Editorial Scanning for the Full Picture: Building Evidence for Imaging After In-Hospital Cardiac Arrest Nicholas J. Johnson, Kelley R.H. Branch Chest 2026; 170: 15-16 https://doi.org/10.1016/j.chest.2026.02.011 The 2025 American Heart Association (AHA) guidelines mark an important evolution in postcardiac arrest care by introducing a Class IIb recommendation that it may be reasonable to perform advanced imaging after the return of spontaneous...

Invited Commentary  Potential Transformative Impact of Autonomous Oxygen Delivery in Hospitalized Patients Melanie F. Weingart, Michael A. Matthay JAMA Intern Med Published Online: August 3, 2026 doi: 10.1001/jamainternmed.2026.4038 Oxygen is one of the most commonly administered therapies used in patients with acute illness and hypoxemic respiratory failure, owing to major advances in its delivery and monitoring over the past century. Despite its ubiq...

JOURNAL ARTICLE EDITOR'S CHOICE Another Point Goes to Team Short Course: Implications of the BALANCE Trial Post Hoc Analysis for Pseudomonas aeruginosa Bloodstream Infections Leila S Hojat, Emily S Spivak Clinical Infectious Diseases, Volume 83, Issue 1, 15 July 2026, Pages 48–50, https://doi.org/10.1093/cid/ciag145 Pseudomonas aeruginosa (PA) is one of the most important contributors to the morbidity and mortality attributable to multidrug...

Comment Can better oral care reduce non-ventilator hospital-acquired pneumonia? Catia Cilloniz, Michael Klompas Lancet Infect Dis Available online 8 June 2026 https://doi.org/10.1016/S1473-3099(26)00282-3Get rights and content Non-ventilator hospital-acquired pneumonia (NV-HAP) is the most frequent and deadly health-care-associated infection.1, 2 The Hospital Acquired Pneumonia Prevention (HAPPEN) trial, presented by Nicole M White and colleagues in The Lan...

Comment From PROSpect to the bedside: contextual and pathophysiological considerations Jeremy M Loberger, Robinder G Khemani Lancet 2026; 408: 1788-1789 https://doi.org/10.1016/S0140-6736(26)02054-4 Paediatric acute respiratory distress syndrome (PARDS) is a common, severe manifestation of direct or indirect lung injury in children. Management focuses on the careful implementation of lung protective strategies with high-frequency oscillatory ventilation (HF...