Targeting Medication Errors with Systems Approach In ICU Wed, 4 Feb 2026 Medication errors remain a major source of preventable harm in healthcare systems worldwide, contributing to significant morbidity, mortality and financial burden. Evidence indicates that a substantial proportion of hospitalised patients experience harm linked to adverse events, with medication-related incidents among the most frequent contributors. These errors can arise at any s...

Validating SOFA-2 in Sepsis and Integration of Supplementary Immune Markers In Sepsis Tue, 17 Feb 2026 The Sequential Organ Failure Assessment (SOFA) score is a cornerstone tool in intensive care medicine. Rather than serving primarily as a mortality predictor, it was designed to assess and monitor organ dysfunction in critically ill patients. It forms part of the diagnostic framework for sepsis, where an acute increase of two or more SOFA points const...

ICU Eco-Audit Reduces Resource Use In ICU Wed, 4 Feb 2026 Environmental sustainability is becoming an operational concern within intensive care units, where energy use, medications and single-use medical devices account for a substantial share of resource consumption. Previous benchmarking work has identified specific “hotspots” associated with high material mass and environmental impact, particularly non-sterile gloves, personal protective equipment, ...

Predictive Models for Mortality in Cardiogenic Shock In ICU Thu, 5 Feb 2026 Cardiogenic shock is a time-critical, life-threatening condition characterised by low cardiac output, tissue hypoperfusion and progressive organ failure. Despite advances in treatment and mechanical circulatory support (MCS), mortality remains high. Accurate prognostication is essential to guide clinical decisions, allocate resources, and facilitate communication with patients ...

Comment Treating penicillin-susceptible Staphylococcus aureus bacteraemia: confusing the issue with facts Annette C Westgeest, Vance G Fowler Jr Lancet Available online 17 June 2026 https://doi.org/10.1016/S0140-6736(26)00857-3 Staphylococcus aureus is a leading cause of bacteraemia, responsible for over a million deaths annually. Despite its ubiquity, the quality of evidence upon which clinicians make treatment decisions on bacteraemia is surprisingly...

Airway Management in Patients With Obesity In ICU Tue, 26 May 2026 A new review examines the unique challenges of airway management in critically ill adults with obesity and outlines evidence-based strategies to reduce peri-intubation complications. The article emphasises that obesity is increasingly prevalent worldwide and now affects a substantial proportion of patients admitted to ICUs. Between 25% and 40% of ICU admissions involve patients with obe...

Editorial  Prone Positioning in Viral Bronchiolitis—Back to the Back? Joseph G. Kohne, Susan R. Conway, Steven L. Shein JAMA Published Online: June 17, 2026 doi: 10.1001/jama.2026.11742 Acute viral bronchiolitis is the most common diagnosis in US children’s hospitals, and respiratory failure is the costliest diagnosis across all pediatric acute care.1 Despite the prevalence of this condition and its impact on children, families, and health systems, evi...

Stepwise Clinical and Diagnostic Strategy for Coma In ICU Thu, 14 May 2026 A narrative review presents a structured, physiology-based diagnostic strategy for patients with coma of unknown origin. Coma is defined as a state of unarousable unresponsiveness characterised by the complete absence of both arousal and awareness. It represents one of the most urgent and diagnostically challenging conditions in acute care, particularly when there is no obvious ...

Extracorporeal Life Support and Modification of Haemostasis In ICU Thu, 14 May 2026 The ELMOH (ExtracorporeaL life support and Modification Of Hemostasis) trial investigated how coagulation changes during the first 48 hours of extracorporeal membrane oxygenation (ECMO) and whether these changes differ between venovenous (VV) and venoarterial (VA) ECMO. ECMO is increasingly used in critically ill patients with severe respiratory or circulatory failure, ...

Invited Commentary  To Tube or Not to Tube—A Case for Early Enteral Nutrition Yuqi Zhang, Krista Haines, Suresh Agarwal JAMA Surg 2026;161;(6):583. doi:10.1001/jamasurg.2026.1058 The early introduction of enteral feeding after surgery is well recognized as a cornerstone of Enhanced Recovery After Surgery (ERAS) protocols, consistently shown to reduce postoperative infections and mortality across multiple surgical domains. Although prior studies have compa...