Articles Benzylpenicillin versus flucloxacillin or cloxacillin for the treatment of penicillin-susceptible Staphylococcus aureus bacteraemia (SNAP): an international, multicentre, open-label, non-inferiority randomised controlled trial The Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Group Lancet Available online 17 June 2026 https://doi.org/10.1016/S0140-6736(26)00761-0 Summary Background Previously considered rare, penicillin-suscept...

Original Investigation  Health Informatics A Community-Level Digital Health Readiness Index for the US Saif Khairat, John Geracitano, Zhaoqiang Zhou, et al JAMA Netw Open 2026;9;(6):e2619372. doi:10.1001/jamanetworkopen.2026.19372 Key Points Question  Can a census tract-level Digital Health Index (DHI), developed from public data, quantify community readiness for digital care beyond existing indices? F...

ONLINE FIRST (FREE ACCESS) LATEST ARTICLES What’s New in Intensive Care Acute respiratory distress syndrome in patients with obesityDe Jong, A., Berra, L. & Hernández, G. Imaging in Intensive Care Medicine A misleading acute respiratory failure: when infection is not where you expect itPequignot, B., Barraud, D., Stephan, C. et al. Black hole signHayano, S., Tani, N., Toyama, Y. et al. Correspondence Rethinking patient–ventilator asynchronies: ...

Original Investigation  Infectious Diseases Preferences for Infection Prevention in Hospital-Acquired Infections Shalini Elangovan, Sameera Senanayake, Indumathi Venkatachalam, et al JAMA Netw Open 2026;9;(4):e267432. doi:10.1001/jamanetworkopen.2026.7432 Key Points Question  What factors most affect health care professionals’ decisions when selecting infection prevention and control practices for hospita...

Original Investigation  High-Accuracy Performance of a Simplified Binary Triage System in Military Trauma Daniel Gelman, Ram Gelman, Inbal Dym, et al JAMA Surg Published Online: June 17, 2026 doi: 10.1001/jamasurg.2026.2083 Key Points Question  How accurately does a simplified judgment-based binary field triage system identify severely injured trauma casualties during combat operations? Findi...

Original Investigation  Caring for the Critically Ill Patient Prone Positioning in Infants With Acute Bronchiolitis: The PROPOSITIS Randomized Clinical Trial Florent Baudin, Robin Pouyau, Fabien Subtil, et al JAMA Published Online: June 17, 2026 doi: 10.1001/jama.2026.11078 Key Points Question  Does prone positioning reduce escalation of respiratory support in infants aged 6 months or younger...

ORIGINAL ARTICLE Ten-Year Outcomes after CAR T-Cell Therapy for B-Cell Lymphomas Marco Ruella, Luca Paruzzo, Emeline R. Chong, et al N Engl J Med 2026;394:2440-2448 DOI: 10.1056/NEJMoa2518035 Abstract BACKGROUND Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy is a standard treatment for relapsed or refractory B-cell non-Hodgkin lymphomas. Long-term results and curative potential remain uncertain. METHODS We evaluated long-term outcomes ...

ORIGINAL ARTICLE Randomized Trial of Adjunctive Prednisolone for Kawasaki Disease Siyuan Lin, Yuanchen He, Lan He, et al N Engl J Med 2026;394:1480-1490 DOI: 10.1056/NEJMoa2511478 Abstract BACKGROUND The effect of adjunctive glucocorticoids in the primary treatment of Kawasaki disease in unselected patients remains unknown. METHODS In this multicenter, open-label, randomized, controlled trial in China, we assigned participants with newly diagnos...

Research Effect of a clinical decision support system on stroke care quality and outcomes in patients with acute ischaemic stroke (GOLDEN BRIDGE II): cluster randomised clinical trial Xinmiao Zhang, Lingling Ding, Jing Jing, et al BMJ 2026; 392 doi: https://doi.org/10.1136/bmj-2025-085810 (Published 21 March 2026)Cite this as: BMJ 2026;392:e085810  Abstract Objective To evaluate the efficacy of a clinical decision support system (CDSS) on stroke care q...

Original Investigation  MySurgeryRisk Model Predictions of Postoperative Complications and Mortality Yuanfang Ren, Esra Adiyeke, Ziyuan Guan, et al JAMA Surg 2026;161;(6):619-627. doi:10.1001/jamasurg.2026.1112 Key Points Question  Will applying the MySurgeryRisk framework, originally developed and prospectively validated on a single-center dataset, to a large multicenter dataset enhance generalizability wit...