JAMA Guide to Statistics and Methods  July 15, 2022 Patient-Reported Outcome Measures in Clinical Research Kevin P. Weinfurt, Bryce B. Reeve JAMA. Published online July 15, 2022. doi:10.1001/jama.2022.11238 Health conditions may cause patients to feel ill and have impaired functioning in their daily lives. Thus, it is important to assess how patients are feeling and functioning when evaluating the effects of interventions to prevent or treat ...