Practice Rapid Recommendations A living WHO guideline on drugs for covid-19 Bram Rochwerg, Reed AC Siemieniuk, Thomas Agoritsas, et al BMJ 2020; 370: m3379 doi: https://doi.org/10.1136/bmj.m3379 (Published 04 September 2020) Abstract Clinical question What is the role of drug interventions in the treatment of patients with covid-19? New recommendation Increased attention on ivermectin as a potential treatment for covid-19 triggered this recomm...

[2021年1月25日，WHO在其官方网站发布了新版新冠肺炎诊疗指南。现简要介绍新版指南的改动情况，供临床医生参考] COVID-19 Clinical management: living guidance https://www.who.int/publications/i/item/WHO-2019-nCoV-clinical-2021-1 注：新版指南增加了有条件推荐(conditional recommendation)以及最佳实践声明(Best practice statement)。 筛查、分诊与临床评估：早期识别新冠肺炎患者 （有条件推荐）：对于门诊或医院评估的任何严重程度的新冠肺炎患者，我们建议根据临床判断（包括考虑到...

表1. 怀疑或确诊产ESBL肠杆菌感染的推荐抗生素治疗选择（假设对表格中列举的抗生素体外敏感） 表2. 耐碳青霉烯肠杆菌(CRE)感染的推荐抗生素治疗选择（假设对表格中列举的抗生素体外敏感） 表3. 难治性耐药(DTR)铜绿假单胞菌感染的推荐抗生素治疗选择（假设对表格中列举的抗生素体外敏感）

Editorials Remdesivir: a pendulum in a pandemic lan S Schwartz, Emily L Heil, Erin K McCreary BMJ 2020; 371: m4560 doi: https://doi.org/10.1136/bmj.m4560 (Published 24 November 2020) New guidance challenges remdesivir use for patients with covid-19 Covid-19 has claimed over a million lives globally and devastated healthcare systems, economies, and societal welfare. Determining effective, safe, and scalable prevention and treatment measures is the top priori...

A living WHO guideline on drugs for covid-19 Bram Rochwerg, Thomas Agoritsas, François Lamontagne, et al BMJ 2020;370:m3379 doi: https://doi.org/10.1136/bmj.m3379 (Published 04 September 2020) Abstract Clinical question What is the role of drug interventions in the treatment of patients with covid-19? New recommendation The latest version of this WHO living guidance focuses on remdesivir, following the 15 October 2020 preprint...

ICU Management & Practice, Volume 20 - Issue 1, 2020 Vasoactive Agent Management for Haemodynamic Support in COVID-19 Patients An overview of the Surviving Sepsis Guidelines for the vasoactive agent management of COVID-19 patients with septic shock and the use of arginine vasopressin in this patient population. The SARS-CoV-2 has caused a global health crisis. Thousands of people across the globe have been affected by COVID-19. Clinicians are in urgent n...

张少雷译 感染控制: 对于在COVID-19患者身上进行有可能产生气溶胶操作的医护人员，COVID-19治疗指南小组(the Panel)建议使用合适的呼吸面罩(N-95呼吸面罩)或动力空气净化呼吸面罩，而不是外科口罩，此外还应使用其他个人防护装备，即手套、防护服及面屏、护目镜等护眼用具(AIII)。 建议对于COVID-19患者，如果可能，由具有丰富气道管理经验的医务人员进行气管内插管(AIII)。 建议如果可能的话，可以通过可视喉镜进行插管(CIII)。 血流动力学支持: 建议去甲肾上腺素作为首选的升压药物(AII)。 ...

ESPEN expert statements and practical guidance for nutritional management of individuals with sars-cov-2 infection. Clinical Nutrition , https://doi.org/10.1016/j.clnu.2020.03.022 新冠肺炎不良预后与高病死率与免疫功能低下、高龄、合并基础疾病、肥胖以及营养不良密切相关，炎症反应与并发的全身感染（sepsis）使病情进一步加重。 ICU住院时间延长本身就可导致病人获得性营养不良与严重的骨骼肌丧失。最近，ESPEN（European Society for Clinical Nutrition and Metabolism，）为COVID-...

Persons at Risk for Infection with SARS-CoV-2 Pre-Exposure Prophylaxis The COVID-19 Treatment Guidelines Panel (the Panel) does not recommend the use of any agents for SARS-CoV-2 pre-exposure prophylaxis (PrEP) outside the setting of a clinical trial(AIII). Post-Exposure Prophylaxis The Panel does not recommend the use of any agents for SARS-CoV-2 post-exposure prophylaxis (PEP) outside the setting of a clinical trial (AIII). Management of Persons...

COVID-19: The Surviving Sepsis Campaign Guidelines The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing rapidly spreading illness, and COVID-19 has now affected thousands of people around the world. Clinicians are in urgent need of guidance to deal with this crisis. A panel of 36 experts from 12 countries proposed 53 questions, reviewed literature for direct and indirect evidence on the management of COVID-19 in critically ill patients in the ...