Transfusion of Fresh Frozen Plasma and Platelets in Critically Ill Adults: An American College of Chest Physicians Clinical Practice Guideline Angel Coz Yataco, Israa Soghier, Paul C. Hébert, et al Chest 2025; 168: 661-676 DOI: 10.1016/j.chest.2025.02.029 Abstract Background Platelets and fresh frozen plasma (FFP) are frequently administered to critically ill patients. Considering the variability in indications and thresholds guiding these transfusions, ...

Special Communication  May 29, 2025 Platelet Transfusion2025 AABB and ICTMG International Clinical Practice Guidelines Ryan A. Metcalf, Susan Nahirniak, Gordon Guyatt, et al JAMA. Published online May 29, 2025. doi:10.1001/jama.2025.7529 Abstract Importance  Platelet transfusion is a frequent procedure with benefits and risks. Objective  To provide recommendations in adult and pedia...

Critical Care: Guidelines and Consensus Statements Use of Intravenous Albumin: A Guideline From the International Collaboration for Transfusion Medicine Guidelines Jeannie Callum, Nikolaos J. Skubas, Aarti Bathla, et al Chest 2024; 166: 321-338 Background Albumin is used commonly across a wide range of clinical settings to improve hemodynamics, to facilitate fluid removal, and to manage complications of cirrhosis. The International Collaboration for Transfu...

JAMA Clinical Guidelines Synopsis  May 7, 2025 Use of Intravenous Albumin Stephen Fuest, Cristina Fischer, Jason T. Alexander JAMA. Published online May 7, 2025. doi:10.1001/jama.2025.3792 Guideline title Use of Intravenous Albumin: A Guideline From the International Collaboration for Transfusion Medicine Guidelines Release date March 4, 2024 Developer International Collaboration for Transfusion Medicine Guidelines Fun...

Article A consensus of European experts on the definition of ventilator-associated pneumonia recurrences obtained by the Delphi method: the RECUVAP study Antoine Gaillet, Charles-Edouard Luyt, Jean-Francois Timsit, et al Intensive Care Med 2025; 51: 506-517 Abstract Background There are recognized diagnostic criteria for a first ventilator-associated pneumonia (VAP) episode, but not for recurrences. Many randomized clinical trials (RCTs) have used the re...

Article European Society of Intensive Care Medicine (ESICM) 2025 clinical practice guideline on fluid therapy in adult critically ill patients: part 2—the volume of resuscitation fluids Conference Reports and Expert Panel Intensive Care Med 2025; 51: 461-477 Published: 31 March 2025 Abstract Objective This European Society of Intensive Care Medicine (ESICM) guideline provides evidence-based recommendations on the volume of early resuscitation flu...

Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM Oliver A Cornely, Rosanne Sprute, Matteo Bassetti, et al Lancet Infect Dis 2025; 25: e280-e293 Summary Candida species are the predominant cause of fungal infections in patients treated in hospital, contributing substantially to morbidity and mortality. Candidaemia and other forms of invasive candidiasis primarily affect patients who ar...

Critical Care: Guideline and Consensus Statement Red Blood Cell Transfusion in Critically Ill Adults: An American College of Chest Physicians Clinical Practice Guideline Angel O. Coz Yataco, Israa Soghier, Paul C. Hébert, et al Chest Available online 26 September 2024 https://doi.org/10.1016/j.chest.2024.09.016 Background Blood products frequently are administered to critically ill patients. Considering recent trials and practice variability, a comprehensiv...

Consensus Statement  Critical Care Medicine February 3, 2025 Extracorporeal Blood Purification in European Pediatric Intensive Care Units: A Consensus Statement Gabriella Bottari, Emanuele Buccione, Benan Bayrakci, et al JAMA Netw Open. 2025;8(2):e2457657. doi:10.1001/jamanetworkopen.2024.57657 Abstract Importance  Important advances have been made in extracorporeal blood purification ther...

Guidelines for Neurological Care During and After ECMO In ICU Mon, 9 Sep 2024 Extracorporeal membrane oxygenation (ECMO) use is on the rise, but patients on ECMO often experience major complications, such as acute brain injury (ABI), which doubles or triples in-hospital mortality rates. ABI is more prevalent in venoarterial (VA) ECMO compared to venovenous (VV) ECMO, especially in cases involving extracorporeal cardiopulmonary resuscitation (ECPR), wit...