ICU Management & Practice, Volume 21 - Issue 1, 2021 Evidence-Based Management of Atrial Fibrillation The 2020 ESC Guidelines and the addition of Landiolol An overview of the updated guidelines for the diagnosis and management of atrial fibrillation, developed in association with the European Association for Cardio-Thoracic Surgery. The European Society of Cardiology (ESC) provides a range of scientific and educational activities, such as the producti...

Selection Criteria for Lung Transplantation in COVID-19 Patients In May 2020, a team led by thoracic surgeon Konrad Hoetzenecker of the Department of Surgery of MedUni Vienna and Vienna General Hospital performed a lung transplant on a 44-year-old patient who had been seriously ill with COVID-19. She thus became the first patient in Europe to receive a lung transplant for this indication. The Vienna lung transplantation programme now plays a leading role in an i...

EORTC/MSGERC Definitions of Invasive Fungal Diseases: Summary of Activities of the Intensive Care Unit Working Group Matteo Bassetti, Elie Azoulay, Bart-Jan Kullberg, et al Clin Infect Dis 2021; 72(S2): S121-7 INVASIVE CANDIDIASIS Defining Proven and Probable Invasive Candidiasis in the Intensive Care Unit After several rounds of review and discussion, the proposed definition for proven IC by the ICU Working Group required definitive evidence of the organis...

Choosing Wisely: The Next Five Recommendations In 2010, Howard Brody, a medical ethicist and family physician, authored "Medicine's Ethical Responsibility for Healthcare Reform - The Top Five List". His list challenged medical societies to identify five interventions in healthcare that were overused, and that did not provide patient benefit. Following the same logic, the American Board of Internal Medicine (ABIM) soon launched its "Choosing Wisely" campaign that also c...

CDC Interim Guidelines for Fully Vaccinated People Efforts to end the COVID-19 pandemic finally became possible when, in December 2020, the FDA authorised the use of the first COVID-19 vaccine, manufactured by Pfizer-BioNTech. Soon after, two additional vaccines from Moderna and Johnson & Johnson also received emergency authorisation for use. As of 8 March 2021, over 31 million people in the U.S. have completed their vaccination.  As the number of ...

全剂量接种疫苗人群临时公共卫生建议 2021年3月8日更新 要点 这是针对全剂量接种疫苗人群的第一套公共卫生建议。本指导方针将根据SARS-CoV-2的社区传播水平、全剂量接种疫苗人口比例以及COVID-19疫苗科学的迅速发展而进行更新和扩充。 出于本指导方针的目的，接种2剂COVID-19系列疫苗（辉瑞生物科技或莫德纳）的第二剂2周后，或在接种单剂疫苗（强生[J&J]/杨森）2周后，人们才被认为完成全剂量接种疫苗。 以下建议适用于非医疗护理环境。有关医疗护理环境的相关信息，请参阅应对COVID-19免疫...

Practice Rapid Recommendations A living WHO guideline on drugs for covid-19 Bram Rochwerg, Reed AC Siemieniuk, Thomas Agoritsas, et al BMJ 2020; 370: m3379 doi: https://doi.org/10.1136/bmj.m3379 (Published 04 September 2020) Abstract Clinical question What is the role of drug interventions in the treatment of patients with covid-19? New recommendation Increased attention on ivermectin as a potential treatment for covid-19 triggered this recomm...

[2021年1月25日，WHO在其官方网站发布了新版新冠肺炎诊疗指南。现简要介绍新版指南的改动情况，供临床医生参考] COVID-19 Clinical management: living guidance https://www.who.int/publications/i/item/WHO-2019-nCoV-clinical-2021-1 注：新版指南增加了有条件推荐(conditional recommendation)以及最佳实践声明(Best practice statement)。 筛查、分诊与临床评估：早期识别新冠肺炎患者 （有条件推荐）：对于门诊或医院评估的任何严重程度的新冠肺炎患者，我们建议根据临床判断（包括考虑到...

表1. 怀疑或确诊产ESBL肠杆菌感染的推荐抗生素治疗选择（假设对表格中列举的抗生素体外敏感） 表2. 耐碳青霉烯肠杆菌(CRE)感染的推荐抗生素治疗选择（假设对表格中列举的抗生素体外敏感） 表3. 难治性耐药(DTR)铜绿假单胞菌感染的推荐抗生素治疗选择（假设对表格中列举的抗生素体外敏感）

Editorials Remdesivir: a pendulum in a pandemic lan S Schwartz, Emily L Heil, Erin K McCreary BMJ 2020; 371: m4560 doi: https://doi.org/10.1136/bmj.m4560 (Published 24 November 2020) New guidance challenges remdesivir use for patients with covid-19 Covid-19 has claimed over a million lives globally and devastated healthcare systems, economies, and societal welfare. Determining effective, safe, and scalable prevention and treatment measures is the top priori...