Medical News in Brief  February 8, 2023 Updated COVID-19 Guidance for People Who Are Immunocompromised Emily Harris JAMA. Published online February 8, 2023. doi:10.1001/jama.2023.1176 In late January, the US Food and Drug Administration announced that Evusheld (the combined monoclonal antibodies tixagevimab and cilgavimab) is not currently authorized for emergency use because it’s likely ineffective against more than 90% o...

JAMA Clinical Guidelines Synopsis  September 15, 2022 Management of Heart Failure Mark N. Belkin, Adam S. Cifu, Sean Pinney JAMA. 2022;328(13):1346-1347. doi:10.1001/jama.2022.16667 Guideline title 2022 American College of Cardiology (ACC)/American Heart Association AHA)/Heart Failure Society of America (HFSA) Guidelines for the Management of Heart Failure Release date April 1, 2022 Prior versions 2017 ACC/AHA/HFSA Focused Update o...

JAMA Clinical Guidelines Synopsis  September 15, 2022 Management of Heart Failure Mark N. Belkin, Adam S. Cifu, Sean Pinney JAMA. Published online September 15, 2022. doi:10.1001/jama.2022.16667 Guideline title 2022 American College of Cardiology (ACC)/American Heart Association AHA)/Heart Failure Society of America (HFSA) Guidelines for the Management of Heart Failure Release date April 1, 2022 Prior versions 2017 ACC/AH...

JAMA Clinical Guidelines Synopsis  August 8, 2022 Treatment of Clostridioides difficile Infection Kanika Sehgal, Adam S. Cifu, Sahil Khanna JAMA. Published online August 8, 2022. doi:10.1001/jama.2022.12251 Guideline title ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections Release date May 18, 2021 Prior version 2013 Developer American College o...

US Preventive Services Task Force  Recommendation Statement August 23/30, 2022 Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement US Preventive Services Task Force JAMA. 2022;328(8):746-753. doi:10.1001/jama.2022.13044 Abstract Importance  Cardiovascular disease (CVD) is the leading cause of morbidity and death in the US and is the cause of more...

PULMONARY VASCULAR: GUIDELINES AND CONSENSUS STATEMENTS| VOLUME 162, ISSUE 1, P213-225, JULY 01, 2022 Thromboprophylaxis in Patients With COVID-19: A Brief Update to the CHEST Guideline and Expert Panel Report Lisa K. Moores, Tobias Tritschler, Shari Brosnahan, et al Chest 2022; 162: 213-225 Published:February 12, 2022 DOI:https://doi.org/10.1016/j.chest.2022.02.006 Background Patients hospitalized with COVID-19 often exhibit markers of a ...

Infectious Diseases Society of America Guidance on the Treatment of AmpC β-Lactamase–Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections Pranita D. Tamma, Samuel L. Aitken, Robert A. Bonomo, et al Clinical Infectious Diseases 2022; 74(12): 2089-2114 AMPC Β-LACTAMASE–PRODUCING ENTEROBACTERALES Question 1: Which Enterobacterales Should Be Considered at Moderate to High Risk for Clinically Signific...

US Preventive Services Task Force  Recommendation Statement June 21, 2022 Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement US Preventive Services Task Force JAMA. 2022;327(23):2326-2333. doi:10.1001/jama.2022.8970 Abstract Importance  According to National Health and Nutrition Examination Survey data, 52% of surveyed US a...

Research Special Paper Visualising harms in publications of randomised controlled trials: consensus and recommendations Rachel Phillips, Suzie Cro, Graham Wheeler, et al BMJ 2022; 377 doi: https://doi.org/10.1136/bmj-2021-068983 (Published 16 May 2022)Cite this as: BMJ 2022;377:e068983 Abstract  Objective To improve communication of harm in publications of randomised controlled trials via the development of recommendations for visually presen...

JAMA Clinical Guidelines Synopsis May 16, 2022 Antithrombotic Therapy for Venous Thromboembolism Christopher D. Jackson, Adam S. Cifu, Desirée C. Burroughs-Ray JAMA. Published online May 16, 2022. doi:10.1001/jama.2022.7325 Guideline title Antithrombotic Therapy for VTE Disease: Second Update of the CHEST Guideline and Expert Panel Report Developer and funding source American College of Chest Physicians Release date August 2...