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[JAMA Netw Open发表论文]:新冠疫情隔离与挪威青少年的精神健康
2024年09月17日 时讯速递, 进展交流 [JAMA Netw Open发表论文]:新冠疫情隔离与挪威青少年的精神健康已关闭评论

Original Investigation 

Public Health

July 12, 2024

COVID-19 Pandemic Quarantines and Mental Health Among Adolescents in Norway

Johanne H. Pettersen, Laurie J. Hannigan, Kristin Gustavson, et al

JAMA Netw Open. 2024;7(7):e2422189. doi:10.1001/jamanetworkopen.2024.22189

Key Points

Question  How were stringent public health measures and quarantine during the COVID-19 pandemic associated with mental distress among Norwegian adolescents, and did vulnerability factors moderate the associations?

Findings  In this cohort study of 7787 participants, stricter public health measures and quarantine were associated with adolescent mental distress. Younger adolescents, those with parents with lower education, or those with lower genetic liability to depression showed particularly elevated mental distress by more frequent quarantines.

Meaning  These findings suggest the need for targeted support to protect adolescent well-being during future crises and emphasize the possible ongoing risk of mental health problems in adolescents following the COVID-19 pandemic.

Abstract

Importance  Adolescence is a critical developmental phase when mental health disorders, such as anxiety and depression, often emerge. Stringent public health measures and quarantine mandates during the COVID-19 pandemic could threaten adolescent mental health.

Objective  To investigate the associations of public health measures and quarantine experiences with mental distress among Norwegian adolescents and to explore if certain vulnerability factors moderate these associations.

Design, Setting, and Participants  This longitudinal cohort study used repeated measures to capture variations in mental distress explained by the stringency of public health measures and quarantine experiences. Data from the Norwegian Mother, Father, and Child cohort study were linked to national health registries and a national stringency index from April 1, 2020, to February 17, 2021. Participant included 7787 Norwegian adolescents aged 16 to 18 years. Data were analyzed from October 2022 to October 2023.

Exposures  Stringency index of public health measures and quarantine experiences including recent quarantine (within the last 2 weeks) and quarantine frequency (cumulative number of quarantine episodes).

Main Outcome and Measures  Mental distress was measured using the Hopkins Symptom Checklist across 6 data collection waves.

Results  In this study, 7787 participants were included in the analysis (4473 female [57%]; mean [SD] age, 17.0 [0.6] years). Stringent public health measures (β = 0.18; SE, 0.02; P < .001), recent quarantine (β = 0.11; SE, 0.02; P < .001), and frequent quarantine (β = 0.08; SE, 0.01; P < .001) were associated with higher levels of mental distress. The associations between public health measures and mental distress were not moderated by sex, age, prepandemic anxiety or depression, or genetic liability for mental health conditions. Frequency of quarantine appeared to be more strongly associated with mental distress among younger adolescents (β = −0.04; SE, 0.01; P = .008), those with parents with lower education (β = −0.04; SE, 0.01; P = .007), and those with lower genetic risk for depression (β = −0.03; SE, 0.01; P = .006).

Conclusions and Relevance  In this study, younger adolescents, those with parents with lower education, or those with low genetic liability for depression appeared more vulnerable when being quarantined several times. These findings emphasize the need for targeted support strategies to better protect adolescent well-being during future crises. Adolescents who experienced increased mental distress during the COVID-19 pandemic may be at risk of continued mental health problems and in need of ongoing support.

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