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[JAMA Netw Open发表论文]:治疗明显高血压过程中依从临床指南的障碍
2024年10月07日 时讯速递, 进展交流 [JAMA Netw Open发表论文]:治疗明显高血压过程中依从临床指南的障碍已关闭评论

Original Investigation 

Cardiology

August 6, 2024

Barriers to Optimal Clinician Guideline Adherence in Management of Markedly Elevated Blood Pressure: A Qualitative Study

Yuan Lu, Oreoluwa Arowojolu, Xiaoliang Qiu, et al

JAMA Netw Open. 2024;7(8):e2426135. doi:10.1001/jamanetworkopen.2024.26135

Key Points

Question  What are the plausible scenarios and factors contributing to clinician nonadherence to the guidelines for hypertension management?

Findings  In this qualitative study of 100 patients with markedly elevated blood pressure, 3 domains of suboptimal adherence were developed (clinician-related scenarios, patient-related scenarios, and clinical complexity–related scenarios) and several plausible contributing factors were identified, including a lack of clear protocols and processes to implement guidelines, infrastructure limitations, clinicians’ lack of autonomy and authority, excessive workload, time constraints, and clinician belief or perception.

Meaning  This study introduced a taxonomy poised to inform targeted interventions, thereby enhancing guideline adherence and elevating care quality for severe hypertension.

Abstract

IMPORTANCE  Hypertension poses a substantial public health challenge. Despite clinical practice guidelines for hypertension management, clinician adherence to these guidelines remains suboptimal.

OBJECTIVE  To develop a taxonomy of suboptimal adherence scenarios for severe hypertension and identify barriers to guideline adherence.

DESIGN, SETTING, and PARTICIPANTS  This qualitative content analysis using electronic health records (EHRs) of Yale New Haven Health System included participants who had at least 2 consecutive visits with markedly elevated blood pressure (BP; defined as at least 2 consecutive readings of systolic BP ≥160 mm Hg and diastolic BP ≥100 mm Hg) between January 1, 2013, and December 31, 2021, and no prescription for antihypertensive medication within a 90 days of the second BP measurement. Data analysis was conducted from January to December 2023.

MAIN OUTCOMES AND MEASURES  The primary outcome was scenarios and influencing factors contributing to clinician nonadherence to the guidelines for hypertension management. A thematic analysis of EHR data was conducted to generate a pragmatic taxonomy of scenarios of suboptimal clinician guideline adherence in the management of severe hypertension.

RESULTS  Of the 20 654 patients who met criteria, 200 were randomly selected and thematic saturation was reached after analyzing 100 patients (mean [SD] age at index visit, 66.5 [12.8] years; 50 female [50%]; 8 Black [8%]; 5 Hispanic or Latino [5%]; 85 White [85%]). Three content domains emerged: (1) clinician-related scenarios (defined as noninitiation or nonintensification of treatment due to issues relating to clinician intention, capability, or scope), which included 2 subcategories (did not address and diffusion of responsibility); (2) patient-related scenarios (defined as noninitiation or nonintensification of treatment due to patient behavioral considerations), which included 2 subcategories (patient nonadherence and patient preference); and (3) clinical complexity–related scenarios (defined as noninitiation or nonintensification of treatment due to clinical situational complexities), which included 3 subcategories (diagnostic uncertainty, maintenance of current intervention, and competing medical priorities).

CONCLUSIONS AND RELEVANCE  In this qualitative study of EHR data, a taxonomy of suboptimal adherence scenarios for severe hypertension was developed and barriers to guideline adherence were identified. This pragmatic taxonomy lays the foundation for developing targeted interventions to improve clinician adherence to guidelines and patient outcomes.

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