ARTICLES OF THE MONTH - APRIL 2019

ORIGINAL ~ Nasal high-flow preoxygenation for endotracheal intubation in the critically ill patient: a randomised clinical trial
Guitton et al.: Nasal high-flow preoxygenation for endotracheal intubation in the critically ill patient: a randomised clinical trial
This is the first randomised multicentre study comparing the use of HFNC with HFFM for the preoxygenation of non-severely hypoxemic patients in the ICU. In this setting, preoxygenation with HFNC could be considered as a valuable device to reduce intubation-related complications.

ORIGINAL ~ Fever-control in critically ill adults. An individual patient data meta-analysis of randomised controlled trials
Young et al.: Fever control in critically ill adults. An individual patient data meta-analysis of randomised controlled trials
An individual level patient data meta-analysis of randomised controlled trials was conducted to compare the outcomes of ICU patients who received more active fever management with the outcomes of patients who received less active fever management. The findings do not support the hypothesis that more active fever management increases survival compared with less active fever management overall, or in patients with limited physiological reserves.

ORIGINAL ~ Structural differences in the diaphragm of patients following controlled vs. assisted and spontaneous mechanical ventilation
Marin-Corral et al.
Structural differences in the diaphragm of patients following controlled vs. assisted and spontaneous mechanical ventilation
Maastricht III donors present less Ventilator-Induced Diaphragm Damage (VIDD) than brain-dead donors, probably due to their ability to stimulate their diaphragm. In this regard, the authors recommend that the period of controlled mechanical ventilation in critically ill ventilated patients should be kept short and that ventilation modes with sustained patient effort should be introduced promptly.
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Correspondence ~ Luregn Schlapbach - Global paediatric critical care research: mind the gaps
Editorial ~ Karim Brohi - Why are bleeding trauma patients still dying?
Original ~ Antoine Vieillard-Baron - Cardiovascular clusters in septic shock combining clinical and echocardiographic parameters: a post hoc analysis
Review ~ Miet Schetz - Obesity in the critically ill: a narrative review
What’s New in Intensive Care ~ Giacomo Grasselli - What’s new in electrical impedance tomography
What’s New in Intensive Care ~ Frederic Michard - Is your smartphone the future of physiologic monitoring?
Find more top quality scientific research and manuscripts in this month's ICM journal here