Research Letter  Physician Work Environment and Well-Being February 24, 2025 Trends in Physician Electronic Health Record Time and Message Volume A Jay Holmgren, Nate C. Apathy, Christine A. Sinsky, et al JAMA Intern Med. Published online February 24, 2025. doi:10.1001/jamainternmed.2024.8138 Physician work is increasingly centered around the electronic health record (EHR), which consumes nearly 50% of sc...

Original Investigation  Physician Work Environment and Well-Being February 24, 2025 Mortality Among US Physicians and Other Health Care Workers Vishal R. Patel, Michael Liu, Christopher M. Worsham, et al JAMA Intern Med. Published online February 24, 2025. doi:10.1001/jamainternmed.2024.8432 Key Points Question  How do mortality rates differ by sex, race, and ethnicity among physicians and ot...

The African Critical Illness Outcomes Study (ACIOS): a point prevalence study of critical illness in 22 nations in Africa The African Critical Illness Outcomes Study (ACIOS) Investigators Lancet 2025; 405: 715-724 Summary Background Critical illness represents a major global health-care burden and critical care is an essential component of hospital care. There are few data describing the prevalence, treatment, and outcomes of critically ill patients in Afri...

Research Discrepancies in neglected tropical diseases burden estimates in China: comparative study of real-world data and Global Burden of Disease 2021 data (2004-2020) Guo-Jing Yang, Han-Qi Ouyang, Zi-Yu Zhao, et al BMJ 2025; 388 doi: https://doi.org/10.1136/bmj-2024-080969 (Published 18 February 2025)Cite this as: BMJ 2025;388:e080969 Abstract Objectives To assess the discrepancies between real-world data and the Global Burden of Disease (GBD) 2021 e...

Research Effect of high flow nasal cannula oxygenation on incidence of hypoxia during sedated gastrointestinal endoscopy in patients with obesity: multicentre randomised controlled trial Leilei Wang, Yuanyuan Zhang, Dan Han, et al BMJ 2025; 388 doi: https://doi.org/10.1136/bmj-2024-080795 (Published 11 February 2025)Cite this as: BMJ 2025;388:e080795 Abstract Objective To determine whether high flow nasal cannula (HFNC) oxygenation can reduce the incid...

Research Letter  February 17, 2025 Heterogeneity of Primary Outcomes in Large Atherosclerotic Cardiovascular Disease Trials Published in Prominent Medical Journals Daniel Shepshelovich, Dafna Yahav, Danielle R. Rome, et al JAMA Intern Med. Published online February 17, 2025. doi:10.1001/jamainternmed.2024.7694 The extent of heterogeneity in end points reported by randomized clinical trials (RCTs) of atherosc...

Research Letter  Health Policy February 19, 2025 Health Care Staffing Shortages and Potential National Hospital Bed Shortage Richard K. Leuchter, Benjo A. Delarmente, Sitaram Vangala, et al JAMA Netw Open. 2025;8(2):e2460645. doi:10.1001/jamanetworkopen.2024.60645 Introduction Between August 2020 and April 2024, US hospitals were mandated to report weekly occupancy to the Department of Health and Human...

A Randomized Controlled Trial of Efficacy and Safety of Fecal Microbiota Transplant for Preventing Recurrent Clostridioides difficile Infection Dimitri M Drekonja, Aasma Shaukat, Yuan Huang, et al Clinical Infectious Diseases, Volume 80, Issue 1, 15 January 2025, Pages 52–60, https://doi.org/10.1093/cid/ciae467 Abstract Background Clostridioides difficile infection (CDI) is the most common cause of healthcare–associated in...

Original Investigation  Critical Care Medicine February 10, 2025 Response to Inhaled Nitric Oxide and Mortality Among Very Preterm Neonates With Pulmonary Hypertension Michelle Baczynski, Dany Weisz, Laura Thomas, et al JAMA Netw Open. 2025;8(2):e2458843. doi:10.1001/jamanetworkopen.2024.58843 Key Points Question  Is there an association between inhaled nitric oxide (iNO) responsiveness and m...

Population Sepsis Incidence, Mortality, and Trends in Hong Kong Between 2009 and 2018 Using Clinical and Administrative Data  Lowell Ling, Jack Zhenhe Zhang, Lok Ching Chang,  et al Clinical Infectious Diseases, Volume 80, Issue 1, 15 January 2025, Pages 91–100, https://doi.org/10.1093/cid/ciad491 Abstract Background Sepsis surveillance using electronic health record (EHR)–based data may provide more accurate epidemiologic esti...