ONLINE FIRST (FREE ACCESS) STANDARD OF CARE IN THE INTENSIVE CARE UNIT Narrative Review Atrial fibrillation in critical illness: state of the artSibley S., Bedford J., Wetterslev M., et al. Editorial Telemedicine in critical careSpies C. D. & Ranzani O. T. LATEST ARTICLES Original Decision analysis model of rapid versus deferred antibiotic initiation in patients with suspected sepsis in the emergency department Hill T. M., Kerivan L. T., Vil...

Article A systematic review and meta-analysis of diagnostic performance comparison between generative AI and physicians Hirotaka Takita, Daijiro Kabata, Shannon L. Walston, et al npj Digital Medicine volume 8, Article number: 175 (2025) Abstract While generative artificial intelligence (AI) has shown potential in medical diagnostics, comprehensive evaluation of its diagnostic performance and comparison with physicians has not been extensively explored. We...

WHO Bacterial Priority Pathogens List In ICU Tue, 22 Apr 2025 Antimicrobial resistance (AMR) poses a significant global health threat, hindering the prevention and treatment of infections caused by bacteria, parasites, viruses, and fungi. Antibiotic-resistant pathogens are particularly problematic, leading to increased mortality and healthcare costs. In 2019, antibiotic-resistant infections caused an estimated 1.27 million deaths globally, with the gre...

Rates of infection with other pathogens after a positive COVID-19 test versus a negative test in US veterans (November, 2021, to December, 2023): a retrospective cohort study Miao Cai, Evan Xu, Yan Xie, et al Lancet Infect Dis Available online 1 April 2025 https://doi.org/10.1016/S1473-3099(24)00831-4 Summary Background SARS-CoV-2 infection leads to post-acute sequelae that can affect nearly every organ system, including the immu...

Invited Commentary  Infectious Diseases April 15, 2025 Optimizing Personal Protective Equipment for a Sustainable Future Meghana A. Gadgil, Preeti Mehrotra JAMA Netw Open. 2025;8(4):e255269. doi:10.1001/jamanetworkopen.2025.5269 The important study by Sutjipto et al1 shows that deescalating personal protective equipment (PPE) requirements for COVID-19 can reduce cost and carbon impacts without compromising safety. This 24-month compar...

ORIGINAL ARTICLE Corynebacterium diphtheriae Outbreak in Migrant Populations in Europe Andreas Hoefer, Helena Seth-Smith, Federica Palma, et al N Engl J Med Published June 4, 2025 DOI: 10.1056/NEJMoa2311981 Abstract BACKGROUND A surge of cases of Corynebacterium diphtheriae infection was observed in reception centers for migrants in Europe beginning in the summer of 2022. Most of the cases were cutaneo...

The Puzzle of Cognitive Impairment After ICU In ICU Tue, 15 Apr 2025 Critically ill patients, particularly those who experience delirium or require invasive mechanical ventilation, are at high risk for long-term cognitive impairments. Ventilator-associated brain injury is an emerging area of research, with experts emphasising the need for improved assessment tools and advanced statistical methods to evaluate brain dysfunction in conditions like acute r...

Editorial  Coagulopathy Treatment in Cardiac Surgery—Pharmacy or Blood Bank? Faisal G. Bakaeen, Mariya A. Geube JAMA Surg Published Online: June 11, 2025 doi: 10.1001/jamasurg.2025.1669 Cardiac surgery is the largest consumer of blood and blood derivatives in all surgical specialties, and it accounts for 15% of the nation’s allocated blood.1 This creates pressure on hospital resources and blood availability to meet transfusion requirements. In add...

Original Investigation  Infectious Diseases April 15, 2025 Plastic Waste and COVID-19 Incidence Among Hospital Staff After Deescalation in PPE Use Stephanie Sutjipto, Aung Hein Aung, Margaret M. L. Soon, et al JAMA Netw Open. 2025;8(4):e255264. doi:10.1001/jamanetworkopen.2025.5264 Key Points Question  Following PPE deescalation in Singapore, what was the incidence of COVID-19 among staff and...

Epinephrine vs Norepinephrine in Children With Septic Shock In Sepsis Tue, 15 Apr 2025 Sepsis remains a major cause of illness and death among children worldwide. Although mortality has decreased due to quality improvement initiatives and clinical guidelines, 4–10% of paediatric sepsis cases still result in death, often due to refractory shock or multiorgan dysfunction. For children with persistent shock despite fluid resuscitation, vasoactive agent...