Intensive Care Medicine
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Seven-Day Profile Publication ~ Alain Combes - Feasibility and safety of extracorporeal CO2 removal to enhance protective ventilation in Acute Respiratory Distress Syndrome: the SUPERNOVA study
Review ~ G. A. Schmidt - Ultrasound-guided vascular access in critical illness
Original ~ Gerald Chi - Extended-duration Betrixaban versus shorter-duration Enoxaparin for Venous Thromboembolism Prophylaxis in critically ill medical patients: an APEX trial sub study
Original ~ Christiane S. Hartog - Narrative reviews from a fraudulent author: reasons to retract
Original ~ J. Marin-Corral - Structural differences in the diaphragm of patients following controlled vs assisted and spontaneous mechanical ventilation
Original ~ Blair Wendlandt - Modifiable elements of ICU supportive care and communication are associated with surrogates’ PTSD symptoms
Understanding the Disease ~ Ewan C. Goligher - Myotrauma in mechanically ventilated patients
Understanding the Disease ~ Shirin K. Frisvold - What respiratory targets should be recommended in patients with brain injury and respiratory failure?
What’s New in Intensive Care Medicine ~ Daniel Azoulay - A new extra-thoracic, in-plane, longitudinal, real-time, ultrasound-guided access to the axillary vein
Imaging in Intensive Care Medicine ~ Panagiota Sotiriou - Massive tricuspid valve regurgitation: sonographic findings of jugular and hepatic veins
专刊:ICU中的器官捐献与移植

Editorial ~ Elco F. M.Wijdicks - Critical synopsis and key questions in brain death determination
Examining the role of the ICU in the the declaration of brain death, based on the expertise of intensivists, neurointensivists and neurosurgeons.

Review ~ Martin Smith - Organ donation after circulatory death: current status and future potential
This review examines exemplar cDCD and uDCD pathways, practical and logistical considerations, as well as ethical concerns and future perspectives.

Review ~ Ignacio Martin-Loeches - Management of donation after brain death (DBD) in the ICU: the potential donor is identified, what's next?
This manuscript highlights the main steps of organ donation, the role of the intensivist and the importance of the development of research into brain death pathophysiology and reversible organ damage.

Review ~ Nancy Kentish-Barnes - A narrative review of family members’ experience of organ donation request after brain death in the critical care setting
Family experience of organ donation is complex and challenges remain that concern all the persons involved in the process.

Review ~ Geert Meyfroidt - Management of the brain-dead donor in the ICU: general and specific therapy to improve transplantable organ quality
A practical overview of the management of the potential organ donor in the ICU.

Editorial ~ Beatriz Domínguez-Gil - Expanding the pool of deceased organ donors
Opportunities to increase the donor pool exist if the legal, ethical, professional and organisational considerations are addressed and the intensive and emergency care communities are engaged.

Understanding the Disease ~ Thomas Bein - Determination of brain death under extracorporeal life support
Brain death determination in ECMO patients is expected to become an increasing occurrence and brain-dead ECMO patients are suitable for organ donation.