Research Christmas 2023: Food and Drink Efficacy of cola ingestion for oesophageal food bolus impaction: open label, multicentre, randomised controlled trial E G Tiebie, E P Baerends, T Boeije, et al BMJ 2023; 383 doi: https://doi.org/10.1136/bmj-2023-077294 (Published 11 December 2023)Cite this as: BMJ 2023;383:e077294 Abstract Objective To determine the efficacy and safety of cola in resolving complete oesophageal food bolus impaction. Design...

Original Investigation  November 17, 2023 Higher-Dose Fluvoxamine and Time to Sustained Recovery in Outpatients With COVID-19: The ACTIV-6 Randomized Clinical Trial Thomas G. Stewart, Paulina A. Rebolledo, Ahmad Mourad, et al JAMA. Published online November 17, 2023. doi:10.1001/jama.2023.23363 Key Points Question  Does 100 mg of fluvoxamine twice daily for 13 days, compared with placebo, shorten symptom duration among outpatient...

Research Letter  November 20, 2023 School Performance in Third Grade After a Full-Day vs Part-Day Preschool Program Arthur J. Reynolds, Nicole E. Smerillo, Suh-Ruu Ou, et al JAMA. Published online November 20, 2023. doi:10.1001/jama.2023.20010 Preschool improves educational outcomes and well-being, especially for economically disadvantaged children.1 Most evidence is from part-day programs. Whether full-day preschool (FDP) promotes susta...

Original Investigation  August 30, 2023 Surgeon Sex and Long-Term Postoperative Outcomes Among Patients Undergoing Common Surgeries Christopher J. D. Wallis, Angela Jerath, Khatereh Aminoltejari, et al JAMA Surg. 2023;158(11):1185-1194. doi:10.1001/jamasurg.2023.3744 Key Points Question  Is there an association between surgeon sex and patients’ long-term postoperative outcomes? Findings  ...

Conservative versus Liberal Oxygenation Targets in Intensive Care Unit Patients (ICONIC): A Randomized Clinical Trial L. Imeen van der Wal,  Chloe C. A. Grim,  Michael R. del Prado, et al Am J Respir Crit Care Med 2023; 208: 770-779 Abstract Rationale: Supplemental oxygen is widely administered to ICU patients, but appropriate oxygenation targets remain unclear. Objectives: This study aimed to determine whether a low-oxygenation strategy would low...

Original Investigation  September 18, 2023 Comparison of Hospital Online Price and Telephone Price for Shoppable Services Merina Thomas, James Flaherty, Jiefei Wang, et al JAMA Intern Med. 2023;183(11):1214-1220. doi:10.1001/jamainternmed.2023.4753 Key Points Question  How well do US hospitals’ online prices posted for shoppable services correlate with their prices for the same service obtained via the te...

ONLINE FIRST (FREE ACCESS) The latest articles published in our Journal, directly in your mailbox. As of this week, we will also share short profiles of our editors, so that you can learn more about the research interests and accomplishments of our team.  LATEST ARTICLES OriginalAssociation of language concordance and restraint use in adults receiving mechanical ventilationGershengorn H. B. et al. Magnesium sulphate in patients with thrombotic thrombocytopenic...

Original Investigation  November 6, 2023 Overnight Stay in the Emergency Department and Mortality in Older Patients Melanie Roussel, Dorian Teissandier, Youri Yordanov, et al JAMA Intern Med. Published online November 6, 2023. doi:10.1001/jamainternmed.2023.5961 Key Points Question  Is spending a night in the emergency department (ED) associated with increased in-hospital mortality and morbidity...

Magnesium sulphate in patients with thrombotic thrombocytopenic purpura (MAGMAT): a randomised, double-blind, superiority trial Lara Zafrani, Emmanuel Canet, Anouk Walter-Petrich, et al Intensive Care Med 2023; 49: 1293-1304 Published: 23 October 2023 Abstract Purpose Studies have suggested benefits from magnesium sulphate in thrombotic thrombocytopenic purpura (TTP). We aimed to measure the effects of magnesium sulphate supplementation on TTP recovery. ...

ARTICLES| VOLUME 4, ISSUE 11, E883-E892, NOVEMBER 2023 Determinants of passive antibody efficacy in SARS-CoV-2 infection: a systematic review and meta-analysis Eva Stadler, Khai Li Chai, Timothy E Schlub, et al Lancet Microbe 2023; 4: E883-E892 Published:November, 2023 DOI:https://doi.org/10.1016/S2666-5247(23)00194-5 Summary Background Randomised controlled trials of passive antibodies as treatment and prophylaxis for COVID-19 have reported variable eff...