Robust Meta-Model for Predicting the Likelihood of Receiving Blood Transfusion in Non-traumatic Intensive Care Unit Patients ALIREZA RAFIEI , RONALD MOORE, TILENDRA CHOUDHARY, et al HEALTH DATA SCIENCE 2024; 4: 0197 DOI: 10.34133/hds.0197 Abstract Background: Blood transfusions, crucial in managing anemia and coagulopathy in intensive care unit (ICU) settings, require accurate prediction for effective resource allocation and patient risk assessment. However...

Original Investigation  January 29, 2025 Benzodiazepine-Free Cardiac Anesthesia for Reduction of Postoperative Delirium: A Cluster Randomized Crossover Trial Jessica Spence, P. J. Devereaux, Shun-Fu Lee, et al JAMA Surg. Published online January 29, 2025 doi:10.1001/jamasurg.2024.6602 Key Points Question  Does an institutional policy restricting benzodiazepines during cardiac anesthesia reduc...

Research Letter  January 27, 2025 Cardiac Biomarker Testing in US Emergency Departments Cian P. McCarthy, Nathan W. Watson, Jason H. Wasfy, et al JAMA Intern Med. Published online January 27, 2025. doi:10.1001/jamainternmed.2024.7554 Patient characteristics and presenting symptoms are used in risk stratification for individuals evaluated in the emergency department (ED) as to their likelihood of having acute...

Original Investigation  January 27, 2025 Termination of Resuscitation Rules for In-Hospital Cardiac Arrest Mathias J. Holmberg, Asger Granfeldt, Ari Moskowitz, et al JAMA Intern Med. Published online January 27, 2025. doi:10.1001/jamainternmed.2024.7814 Key Points Question  Can a clinical decision rule guide termination of resuscitation efforts during in-hospital cardiac arrest? Findings ...

Original Investigation  January 27, 2025 Negative Pressure Dressings to Prevent Surgical Site Infection After Emergency Laparotomy: The SUNRRISE Randomized Clinical Trial SUNRRISE Trial Study Group JAMA. Published online January 27, 2025. doi:10.1001/jama.2024.24764 Key Points Question  Among patients undergoing emergency laparotomy, is there a difference in surgical site infection (SSI) rates when the wound is treated with ...

Original Investigation  Diabetes and Endocrinology January 21, 2025 Use of Albumin-Adjusted Calcium Measurements in Clinical Practice Noémie Desgagnés, James A. King, Gregory A. Kline, et al JAMA Netw Open. 2025;8(1):e2455251. doi:10.1001/jamanetworkopen.2024.55251 Key Points Question  How accurate are the calcium adjustment formulas that are used in clinical practice? Findings  ...

Original Investigation  January 15, 2025 Association Between Surgeon Stress and Major Surgical Complications Jake Awtry, Sarah Skinner, Stephanie Polazzi, et al JAMA Surg. Published online January 15, 2025. doi:10.1001/jamasurg.2024.6072 Key Points Question  Is surgeon physiological stress, as deduced from the sympathovagal balance measured via heart rate variability analysis, associated with pa...

Research Letter  January 2, 2025 Knowledge and Worry Following Review of Standard vs Patient-Centered Pathology Reports Cathryn J. Lapedis, Sophia R. Kurnot, Sarah E. Bergholtz, et al JAMA. Published online January 2, 2025. doi:10.1001/jama.2024.25461 The immediate release of test results to patients via patient portals is required.1,2 Unfortunately, pathology reports contain complex medical terminology...

Original Investigation  Caring for the Critically Ill Patient March 18, 2025 Optimal Vasopressin Initiation in Septic Shock: The OVISS Reinforcement Learning Study Alexandre Kalimouttou, Jason N. Kennedy, Jean Feng, et al JAMA. Published online March 18, 2025. doi:10.1001/jama.2025.3046 Key Points Question  Does a reinforcement learning model identify the optimal initiation rule for vasopress...

Original Investigation  Caring for the Critically Ill Patient March 18, 2025 Inhaled Sedation in Acute Respiratory Distress Syndrome: The SESAR Randomized Clinical Trial Matthieu Jabaudon, Jean-Pierre Quenot, Julio Badie, et al JAMA. Published online March 18, 2025. doi:10.1001/jama.2025.3169 Key Points Question  Is a strategy of inhaled sedation with sevoflurane safe and associated with improved clinical outcomes in patients ...