Original Investigation  October 7, 2024 Arm Position and Blood Pressure Readings: The ARMS Crossover Randomized Clinical Trial Hairong Liu, Di Zhao, Ahmed Sabit, et al JAMA Intern Med. 2024;184(12):1436-1442. doi:10.1001/jamainternmed.2024.5213 Key Points Question  What is the effect of commonly used arm positions on blood pressure (BP) measurements compared to the standard, recommended position? Findi...

Safety and efficacy of early versus delayed acetylsalicylic acid after surgery for spontaneous intracerebral haemorrhage in China (E-start): a prospective, multicentre, open-label, blinded-endpoint, randomised trial Qingyuan Liu, Shaohua Mo, Jun Wu, et al. Lancet Neurol 2024; 23: 1195-1204 https://doi.org/10.1016/S1474-4422(24)00424-1 Summary Background Patients with non-traumatic intracerebral haemorrhage have a substantial risk of major adverse cardiov...

Research Cardiac output-guided haemodynamic therapy for patients undergoing major gastrointestinal surgery: OPTIMISE II randomised clinical trial OPTIMISE II Trial Group BMJ 2024; 387 doi: https://doi.org/10.1136/bmj-2024-080439 (Published 03 December 2024)Cite this as: BMJ 2024;387:e080439 Abstract Objectives To evaluate the clinical effectiveness and safety of a perioperative algorithm for cardiac output-guided haemodynamic therapy in patients underg...

ARTICLES Investigating the effect of enhanced cleaning and disinfection of shared medical equipment on health-care-associated infections in Australia (CLEEN): a stepped-wedge, cluster randomised, controlled trial Katrina Browne, Nicole M White, Philip L Russo, et al Lancet Infect Dis 2024 Online first August 13, 2024 https://doi.org/10.1016/S1473-3099(24)00399-2 Summary Background There is a paucity of high-quality evidence based on clinical endpoints...

Original Investigation  October 14, 2024 Acupuncture vs Sham Acupuncture for Chronic Sciatica From Herniated Disk: A Randomized Clinical Trial Jian-Feng Tu, Guang-Xia Shi, Shi-Yan Yan, et al JAMA Intern Med. 2024;184(12):1417-1424. doi:10.1001/jamainternmed.2024.5463 Key Points Question  Does acupuncture alleviate pain and improve function in patients with chronic sciatica from herniated disk? Findings...

Research Letter  Infectious Diseases November 27, 2024 Testing and Masking Policies and Hospital-Onset Respiratory Viral Infections Theodore R. Pak, Tom Chen, Sanjat Kanjilal, et al JAMA Netw Open. 2024;7(11):e2448063. doi:10.1001/jamanetworkopen.2024.48063 Introduction Most hospitals have stopped testing all patients for SARS-CoV-2 upon admission and requiring masking. Ten hospitals in the Mass Genera...

Original Investigation  Infectious Diseases November 26, 2024 Use of Multiplex Molecular Panels to Diagnose Urinary Tract Infection in Older Adults Kelly M. Hatfield, Sarah Kabbani, Isaac See, et al JAMA Netw Open. 2024;7(11):e2446842. doi:10.1001/jamanetworkopen.2024.46842 Key Points Question  How frequently are multiplex molecular syndromic panels used to diagnose urinary tract infection (U...

ONLINE FIRST (FREE ACCESS) ICU TOOLBOX TOPICAL COLLECTION Editorial How I perform diaphragmatic ultrasound in the intensive care unitHermans G., Demoule A. and Heunks L. Invasive fungal infections in non-neutropenic patientsKreitmann L., Blot S. and Nseir S. My echo checklist in venoarterial ECMO patientsSaura O., Combes A. and Hekimian G. OPEN ACCESS ~ Editorial Managing blood glucose control in the intensive care unit Gunst J., Umpierrez G. E.&nb...

Worldwide trends in diabetes prevalence and treatment from 1990 to 2022: a pooled analysis of 1108 population-representative studies with 141 million participants NCD Risk Factor Collaboration (NCD-RisC) Lancet 2024; 404: 2077-2093 https://doi.org/10.1016/S0140-6736(24)02317-1 Summary Background Diabetes can be detected at the primary health-care level, and effective treatments lower the risk of complications. There are insufficient data on the coverage ...

Research Letter  November 20, 2024 The Quality of Evidence Supporting Clinical Practice Guidelines in General Surgery: A Meta-Analysis Ali B. Abbasi, Adrian Valderrama, Hannah C. Decker, et al JAMA Surg. Published online November 20, 2024. doi:10.1001/jamasurg.2024.4751 Clinical practice guidelines can help patients and physicians make decisions using the best available evidence. Unfortunately, the best avai...