EDUCATION AND CLINICAL PRACTICE: ORIGINAL RESEARCH Impact of Noninvasive Ventilation Before and After Cardiac Surgery for Preventing Cardiac and Pulmonary Complications: A Clinical Randomized Trial Marion Goret, Kevin Pluchon, Raphaël Le Mao, et al Chest 2025; 167: 1727-1736 Abstract Background The immediate postoperative period after heart surgery poses a substantial risk of life-threatening complications, notably acute pulmonary and cardiac failure. Us...

Original Investigation  Surgery June 3, 2025 Three-Dimensional–Printed Models and Shared Decision-Making: A Cluster Randomized Clinical Trial Aimal Khan, Georgina E. Sellyn, Danish Ali, et al JAMA Netw Open. 2025;8(6):e2513187. doi:10.1001/jamanetworkopen.2025.13187 Key Points Question  Compared with usual care practices, does preoperative education for colorectal surgery aided by 3-dimension...

Original Investigation June 3, 2025 Transfusion Strategy Effect on Quality of Life in Patients With Myocardial Infarction and Anemia： A Secondary Analysis of the MINT Randomized Clinical Trial Micah T. Prochaska, Gerard T. Portela, Maria Mori Brooks, et al JAMA Intern Med. Published online June 3, 2025. doi:10.1001/jamainternmed.2025.0654 Key Points Question  Does a liberal (hemoglobin less than 10 ...

Research A village doctor-led mobile health intervention for cardiovascular risk reduction in rural China: cluster randomised controlled trial Xingyi Zhang, Siming Wang, Xingyu Zhou, et al BMJ 2025; 389 doi: https://doi.org/10.1136/bmj-2024-082765 (Published 27 May 2025)Cite this as: BMJ 2025;389:e082765 Abstract Objective To assess the effectiveness of a village doctor-led mobile health intervention on cardiovas...

Research Incidence and prevalence of dementia among US Medicare beneficiaries, 2015-21: population based study Beau Blass, Cassie B Ford, Samir Soneji, et al BMJ 2025; 389 doi: https://doi.org/10.1136/bmj-2024-083034 (Published 20 May 2025)Cite this as: BMJ 2025;389:e083034 Abstract Objective To determine the incidence and prevalence of dementia in a nationally representative cohort of US Medicare beneficiaries, strat...

Original Investigation  June 2, 2025 Robotic vs Laparoscopic Surgery for Middle and Low Rectal Cancer: The REAL Randomized Clinical Trial Qingyang Feng, Weitang Yuan, Taiyuan Li, et al JAMA. Published online June 2, 2025. doi:10.1001/jama.2025.8123 Key Points Question  Can the use of robotic surgery reduce the locoregional recurrence rate of middle and low rectal cancer compared with the use of ...

Research Drug treatments for mild or moderate covid-19: systematic review and network meta-analysis Sara Ibrahim, Reed A C Siemieniuk, María José Oliveros, et al BMJ 2025; 389 doi: https://doi.org/10.1136/bmj-2024-081165 (Published 29 May 2025)Cite this as: BMJ 2025;389:e081165 Abstract Objective To compare the effects of treatments for mild or moderate (that is, non-severe) coronavirus disease 2019 (covid-19). ...

Effects of Janus kinase inhibitors in adults admitted to hospital due to COVID-19: a systematic review and individual participant data meta-analysis of randomised clinical trials Alain Amstutz, Stefan Schandelmaier, Hannah Ewald, et al Lancet Respir Med 2025; 13: 530-544 https://doi.org/10.1016/S2213-2600(25)00055-4 Summary Background Evidence from randomised clinical trials (RCTs) of Janus kinase (JAK) inhibitors—compared with usual care or placebo—in a...

Estimated undertreatment of carbapenem-resistant Gram-negative bacterial infections in eight low-income and middle-income countries: a modelling study Anant Mishra, Rahul Dwivedi, Kim Faure, et al Lancet Infect Dis Available online 30 April 2025 https://doi.org/10.1016/S1473-3099(25)00108-2 Summary Background Carbapenem-resistant Gram-negative (CRGN) bacterial infections are an urgent health threat, especially in low-income and middle-income countries (L...

ONLINE FIRST (FREE ACCESS) ICU TOOLBOX What's New in Intensive Care Acute kidney injury: when and how to start renal replacement therapyBarbar S. D., Wald R. & Quenot J.-P. STANDARD OF CARE IN THE INTENSIVE CARE UNIT What's New in Intensive Care Nutrition and metabolic control for ICU patientsGunst J., Egi M. & Van den Berghe G. LATEST ARTICLES Original ESICM—ESPNIC international expert consensus on quantitative lung ultrasound in intens...