Original Investigation  Emergency Medicine Serious Illness Conversations in the Emergency Department for Older Adults With Advanced Illnesses: A Randomized Clinical Trial Kei Ouchi, Susan D. Block, Dorene M. Rentz, et al JAMA Netw Open 2025;8;(6):e2516582. doi:10.1001/jamanetworkopen.2025.16582 Key Points Question  Does an emergency department (ED)–based intervention to discuss serious illness care goals ...

Research Letter  Continuous Medical Knowledge Assessment Progress Report Score and Hospitalized Patient Outcomes Bradley M. Gray, Jonathan L. Vandergrift, Rebecca S. Lipner, et al JAMA Intern Med Published Online: June 16, 2025 doi: 10.1001/jamainternmed.2025.1730 The American Board of Internal Medicine started offering a Longitudinal Knowledge Assessment (LKA) in 2022 as an alternative to the 10-year long-f...

Collaboration on the optimal timing of anticoagulation after ischaemic stroke and atrial fibrillation: a systematic review and prospective individual participant data meta-analysis of randomised controlled trials (CATALYST) Hakim-Moulay Dehbi, Urs Fischer, Signild Åsberg, et al Lancet Available online 23 June 2025 https://doi.org/10.1016/S0140-6736(25)00439-8 Summary Background The optimal timing of oral anticoagulation for prevention of early ischaemic ...

Original Investigation  April 23, 2025 Long-Term Postoperative Outcomes by Surgeon Gender and Patient-Surgeon Gender Concordance in the US Ryo Ikesu, Hiroshi Gotanda, Tara A. Russell, et al JAMA Surg. Published online April 23, 2025. doi:10.1001/jamasurg.2025.0866 Key Points Question  Are long-term postoperative outcomes different by surgeon gender and patient-surgeon gender concordance? Find...

ONLINE FIRST (FREE ACCESS) STANDARD OF CARE IN THE INTENSIVE CARE UNIT Narrative Review Atrial fibrillation in critical illness: state of the artSibley S., Bedford J., Wetterslev M., et al. Editorial Telemedicine in critical careSpies C. D. & Ranzani O. T. LATEST ARTICLES Original Decision analysis model of rapid versus deferred antibiotic initiation in patients with suspected sepsis in the emergency department Hill T. M., Kerivan L. T., Vil...

Article A systematic review and meta-analysis of diagnostic performance comparison between generative AI and physicians Hirotaka Takita, Daijiro Kabata, Shannon L. Walston, et al npj Digital Medicine volume 8, Article number: 175 (2025) Abstract While generative artificial intelligence (AI) has shown potential in medical diagnostics, comprehensive evaluation of its diagnostic performance and comparison with physicians has not been extensively explored. We...

Rates of infection with other pathogens after a positive COVID-19 test versus a negative test in US veterans (November, 2021, to December, 2023): a retrospective cohort study Miao Cai, Evan Xu, Yan Xie, et al Lancet Infect Dis Available online 1 April 2025 https://doi.org/10.1016/S1473-3099(24)00831-4 Summary Background SARS-CoV-2 infection leads to post-acute sequelae that can affect nearly every organ system, including the immu...

ORIGINAL ARTICLE Corynebacterium diphtheriae Outbreak in Migrant Populations in Europe Andreas Hoefer, Helena Seth-Smith, Federica Palma, et al N Engl J Med Published June 4, 2025 DOI: 10.1056/NEJMoa2311981 Abstract BACKGROUND A surge of cases of Corynebacterium diphtheriae infection was observed in reception centers for migrants in Europe beginning in the summer of 2022. Most of the cases were cutaneo...

Original Investigation  Infectious Diseases April 15, 2025 Plastic Waste and COVID-19 Incidence Among Hospital Staff After Deescalation in PPE Use Stephanie Sutjipto, Aung Hein Aung, Margaret M. L. Soon, et al JAMA Netw Open. 2025;8(4):e255264. doi:10.1001/jamanetworkopen.2025.5264 Key Points Question  Following PPE deescalation in Singapore, what was the incidence of COVID-19 among staff and...

Original Investigation  Postoperative 20% Albumin Infusion and Acute Kidney Injury in High-Risk Cardiac Surgery Patients: The ALBICS AKI Randomized Clinical Trial Yahya Shehabi, Mayurathan Balachandran, Wisam Al-Bassam, et al JAMA Surg Published Online: June 11, 2025 doi: 10.1001/jamasurg.2025.1683 Key Points Question  Is the addition of 20% albumin infusion given postoperatively nephroprotectiv...