Special Communication  Current Topics in Obesity World Health Organization Guideline on the Use and Indications of Glucagon-Like Peptide-1 Therapies for the Treatment of Obesity in Adults Francesca Celletti, Jeremy Farrar, Luz De Regil JAMA 2026;335;(5):434-438. doi:10.1001/jama.2025.24288 Abstract Importance  Obesity is a chronic, relapsing disease affecting over 1 billion people worldwide, driving substantial morbidity, mortality, and ec...

ESICM 2025 Guideline on Fluid Therapy in Adult Critically Ill Patients In Sepsis Wed, 29 Oct 2025 The European Society of Intensive Care Medicine (ESICM) convened an international panel of experts to develop evidence-based guidelines on fluid resuscitation volumes for adult critically ill patients with circulatory failure. This guideline represents Part 2 of a three-part series on fluid management, focusing specifically on resuscitation fluid volumes, ...

Review British Society for Medical Mycology best practice recommendations for the diagnosis of serious fungal diseases: 2025 update Silke Schelenz, Alireza Abdolrasouli, Darius Armstrong-James, et al Lancet Infect Dis Available online 10 November 2025 https://doi.org/10.1016/S1473-3099(25)00550-X Summary The fungal diagnostic landscape is evolving; whereas previously, traditional culture-based methods dominated, most invasive fungal disease is now diagno...

Special Communication  Diagnosis and Treatment of Acute Appendicitis: 2025 Edition of the World Society of Emergency Surgery Jerusalem Guidelines Mauro Podda, Marco Ceresoli, Belinda De Simone, et al JAMA Surg Published Online: January 28, 2026 doi: 10.1001/jamasurg.2025.6218 Abstract Importance  Acute appendicitis is the most common abdominal surgical emergency worldwide and a leading cause of ...

Post-Resuscitation Care: European Resuscitation Council and ESICM Guidelines    In ICU Tue, 28 Oct 2025 The 2025 European Resuscitation Council (ERC) and European Society of Intensive Care Medicine (ESICM) post-resuscitation care guidelines mark their third joint publication, updating the 2021 edition. Building on their first collaboration in 2015, the new guidelines incorporate recent scientific advances and address key aspects of post-cardi...

Chest EIT for Lung Ventilation and Perfusion In ICU Tue, 21 Oct 2025 Electrical impedance tomography (EIT) represents a significant advancement in respiratory monitoring as a non-invasive, radiation-free imaging technique that enables real-time bedside assessment of lung ventilation and perfusion. Despite growing clinical evidence and expanding applications over the past seven years since the first international consensus in 2017, there remains a lack ...

Perspective  The 2025-2030 Dietary Guidelines for Americans Dariush Mozaffarian JAMA Published Online: January 14, 2026 doi: 10.1001/jama.2026.0283 On January 7, 2026, the US Department of Health and Human Services and the US Department of Agriculture (USDA) released the 2025-2030 Dietary Guidelines for Americans (DGAs),1 which by law are revised every 5 years. Interest in this update has been heightened by the Trump administra...

The medical management of acute respiratory distress syndrome Idunn S. Morris, Marcelo Amato, Elias Baedorf Kassis, et al Intensive Care Med 2025 https://doi.org/10.1007/s00134-025-08251-y Non-invasive respiratory supportNon-invasive ventilation Commence early in patients with mild–moderate ARDS If available, helmet over face mask NIV may be better tolerated Uptitrate PEEP, aiming to optimise the work of breathing Titrate pressure support t...

European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2025: post-resuscitation care Jerry P. Nolan, Claudio Sandroni, Alain Cariou, et al Intensive Care Med (2025) https://doi.org/10.1007/s00134-025-08117-3 Abstract The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) have collaborated to produce these post-resuscitation care guidelines for adults, which are based on the Int...

Articles Recommendations for lung ventilation and perfusion assessment with chest electrical impedance tomography in critically ill adult patients: an international evidence-based and expert Delphi consensus study Huaiwu He, Zhanqi Zhao, Tobias Becher, et al eClinicalMedicine 2025; 89: 103575 https://doi.org/10.1016/j.eclinm.2025.103575 Summary Background Electrical impedance tomography (EIT) is a non-invasive, radiation-free imaging technique that al...