D-PRISM: Diagnostic and Treatment Approaches in Pneumonia In ICU Tue, 26 Nov 2024 Pneumonia is a major global health issue, particularly for critically ill patients in ICUs. It encompasses various types, such as community-acquired pneumonia (CAP), hospital-acquired pneumonia (HAP), and ventilator-associated pneumonia (VAP), each with distinct diagnostic and treatment challenges. Annually, pneumonia contributes to over 2.5 million deaths and costs appro...

Original Investigation  January 9, 2025 Changes in Patient Care Experience After Private Equity Acquisition of US Hospitals Anjali Bhatla, Victoria L. Bartlett, Michael Liu, et al JAMA. Published online January 9, 2025. doi:10.1001/jama.2024.23450 Key Points Question  How did measures of patient care experience change after private equity acquisition of US hospitals? Findings  In th...

Original Investigation  January 2, 2025 Esophagectomy Trends and Postoperative Outcomes at Private Equity–Acquired Health Centers Jonathan E. Williams, Sara L. Schaefer, Ryan C. Jacobs, et al JAMA Surg. Published online January 2, 2025. doi:10.1001/jamasurg.2024.5920 Key Points Question  How do postoperative outcomes following esophagectomy at private equity–acquired health centers compare with outco...

Weaning Success Rate With High-Intensity and Sham Inspiratory Muscle Training In ICU Tue, 26 Nov 2024 Failure to wean from mechanical ventilation is common, affecting up to 35% of critically ill patients undergoing the weaning process and significantly worsening outcomes, including prolonged ICU stays, longer hospitalisations, and higher mortality risk. Respiratory muscle weakness, present in over 60% of mechanically ventilated patients, is a major con...

Original Investigation  Surgery January 8, 2025 Surgical Deescalation Within Gynecologic Oncology Alexa Kanbergs, Alexander Melamed, David Viveros-Carreño, et al JAMA Netw Open. 2025;8(1):e2453604. doi:10.1001/jamanetworkopen.2024.53604 Key Points Question  How has surgical deescalation evolved in gynecologic oncology? Findings  In this cohort study of 1 218 490 patients with cer...

Original Investigation  Medical Education January 9, 2025 Program Directors’ Assessments of US Medical Graduates’ Transition to Residency Douglas Grbic, Dorothy A. Andriole, Lindsay Roskovensky, et al JAMA Netw Open. 2025;8(1):e2454048. doi:10.1001/jamanetworkopen.2024.54048 Key Points Question  Do program director assessments of postgraduate year 1 (PGY-1) trainees’ performance during the tr...

Invited Commentary  Pulmonary Medicine January 3, 2025 Evidence-Based Anticoagulation Choice for Acute Pulmonary Embolism Brandon C. Maughan, Christopher Kabrhel, Angela F. Jarman JAMA Netw Open. 2025;8(1):e2452850. doi:10.1001/jamanetworkopen.2024.52850 Systemic anticoagulation is the foundation of treatment for most patients with pulmonary embolism (PE). Guidelines recommend that most patients hospitalized for acute PE who are treated wi...

Adjunctive Vasopressin Initiation for Septic Shock Patients In Sepsis Tue, 26 Nov 2024 Vasoactive drugs are commonly prescribed to critically ill adult patients in ICUs, with noradrenaline being the first-line treatment for septic shock. Vasopressin, a second-line vasopressor, is also widely used. However, there is uncertainty regarding the timing of vasopressin initiation.  The VASST and VANISH trials, which investigated vasopressin in septic ...

Traumatic injury mortality in the Gaza Strip from Oct 7, 2023, to June 30, 2024: a capture–recapture analysis Zeina Jamaluddine, Hanan Abukmail, Sarah Aly DO, et al Lancet Available online 9 January 2025 https://doi.org/10.1016/S0140-6736(24)02678-3 Summary Background Accurate mortality estimates help quantify and memorialise the impact of war. We used multiple data sources to estimate deaths due to traumatic injury in the Gaza Strip between Oct 7, 2023,...

JAMA Clinical Guidelines Synopsis  January 8, 2025 Corticosteroids for Sepsis, Acute Respiratory Distress Syndrome, or Community-Acquired Pneumonia Peggy B. Leung, Andrew M. Davis, Joshua Davis JAMA. Published online January 8, 2025. doi:10.1001/jama.2024.24537 Guideline title 2024 Focused Update: Guidelines on Use of Corticosteroids in Sepsis, Acute Respiratory Distress Syndrome, and Community-Acquired Pneu...