Original Investigation  Nephrology May 27, 2025 Hydrocortisone and Risk Factors for Kidney Replacement Therapy in Septic Shock Lachlan H. Donaldson, Anthony Devaux, Kyle C. White, et al JAMA Netw Open. 2025;8(5):e2512279. doi:10.1001/jamanetworkopen.2025.12279 Key Points Question  In patients with septic shock, is the administration of intravenous hydrocortisone independently associated with subsequent rates of kidney replacem...

Editorials Post-traumatic stress disorder in intensive care survivors Natalia Wege, Mary Princip BMJ 2025; 389 doi: https://doi.org/10.1136/bmj.r841 (Published 07 May 2025)Cite this as: BMJ 2025;389:r841 A role for primary care Advances in intensive care medicine have improved survival rates, yet post-traumatic stress disorder (PTSD) remains a prevalent and often underdiagnosed consequence among patients who are discharged from intensive care units.1 A...

Original Investigation  May 21, 2025 Hemodynamic Impact of Cipepofol vs Propofol During Anesthesia Induction in Patients With Severe Aortic Stenosis: A Randomized Clinical Trial Tingting Ni, Xiaoxia Zhou, Shuguang Wu, et al JAMA Surg. Published online May 21, 2025. doi:10.1001/jamasurg.2025.1299 Key Points Question  Does cipepofol offer superior hemodynamic stability compared to propofol as an anesthesia induction agent? Findings&nb...

Original Investigation  Pediatrics March 25, 2025 Risk Factors for Health Care–Associated Bloodstream Infections in NICUs Julia Johnson, Sudhir Malwade, Sharad Agarkhedkar, et al JAMA Netw Open. 2025;8(3):e251821. doi:10.1001/jamanetworkopen.2025.1821 Key Points Question  What risk factors are associated with neonatal health care–associated bloodstream infections (BSIs) in low-resource settin...

Causes and Consequences of Physician Burnout and the Importance of Well-Being In ICU Mon, 10 Mar 2025 ICU Management & Practice, Volume 25 - Issue 1, 2025 Physician burnout has emerged as a critical issue in healthcare over the past few years, with significant implications for the entire system. This multifaceted problem stems from a combination of individual factors and systemic concerns. By addressing this issue comprehensively, healthcare sy...

Research Effects of a general practitioner-led brief narrative exposure intervention on symptoms of post-traumatic stress disorder after intensive care (PICTURE): multicentre, observer blind, randomised controlled trial Jochen Gensichen, Konrad F R Schmidt, Linda Sanftenberg, et al BMJ 2025; 389 doi: https://doi.org/10.1136/bmj-2024-082092 (Published 07 May 2025)Cite this as: BMJ 2025;389:e082092 Abstract Objective To d...

ONLINE FIRST (FREE ACCESS) ARTIFICIAL INTELLIGENCE IN ICU Editorial Stop asking if AI will replace ICU doctors! Start asking how it will radically transform their practiceGoulenok C., Kentish-Barnes N. & Bougouin W. THE BRAIN IN THE LINE OF FIRE What's New in Intensive Care Carbon dioxide pathophysiology and targets following acute brain injuryTaran S., Sekhon M. & Robba C. STANDARD OF CARE IN THE INTENSIVE CARE UNIT Narrative Review Atr...

Original Investigation  Surgery March 25, 2025 Patient Complexity and Bile Duct Injury After Robotic-Assisted vs Laparoscopic Cholecystectomy Cody Lendon Mullens, Sarah Sheskey, Jyothi R. Thumma, et al JAMA Netw Open. 2025;8(3):e251705. doi:10.1001/jamanetworkopen.2025.1705 Key Points Question  Are patient risk factors and complexity associated with differential rates of bile duct injury in r...

Risk Factors for Subsyndromal Delirium Progression and Mortality In ICU Tue, 25 Mar 2025 Delirium is common in critically ill patients and is linked to poor outcomes like prolonged hospital stays and cognitive impairment. Subsyndromal delirium (SSD) is an intermediate state between no delirium and full delirium, involving cognitive and behavioural abnormalities without meeting DSM-5 criteria for delirium. SSD affects about one-third of ICU patients and...

Original Investigation  March 24, 2025 Avoidable Mortality Across US States and High-Income Countries Irene Papanicolas, Maecey Niksch, Jose F. Figueroa JAMA Intern Med. Published online March 24, 2025. doi:10.1001/jamainternmed.2025.0155 Key Points Question  How did avoidable mortality vary across US states compared with 40 high-income countries between 2009 and 2021? Findings  In this ...