Critical Care Burnout: A Look at Global Burnout Initiatives In ICU Mon, 10 Mar 2025 An overview of literature surrounding the effectiveness of burnout initiatives and implementation of successful programmes from Emory Critical Care Center.   Burnout, a chronic condition of emotional exhaustion, depersonalisation and reduced professional accomplishment, has plagued the global health system for years (Alahmari et al. 2022; De Hert 2020; Moll et ...

Article Higher mortality in female versus male critically ill patients at comparable thresholds of mechanical power: necessity of normalization to functional lung size Dario von Wedel, Simone Redaelli, Boris Jung, et al Intensive Care Med 2025; 51: 624-626 Published: 23 January 2025 Dear Editor, Mechanical power (MP) is an integrative target to minimize risk of ventilator-induced lung injury (VILI) [1]. Estimating the energy delivered by the ventilator t...

Article European Society of Intensive Care Medicine (ESICM) 2025 clinical practice guideline on fluid therapy in adult critically ill patients: part 2—the volume of resuscitation fluids Conference Reports and Expert Panel Intensive Care Med 2025; 51: 461-477 Published: 31 March 2025 Abstract Objective This European Society of Intensive Care Medicine (ESICM) guideline provides evidence-based recommendations on the volume of early resuscitation flu...

Disorders of Consciousness in the ICU In ICU Tue, 18 Mar 2025 A roundtable discussion at the ISICEM Congress in Brussels on disorders of consciousness (DoC) focused on enhancing understanding, diagnosis, and prognosis for patients in ICUs.  The main takeaway is that disorders of consciousness represent a continuum, and diagnoses should not be limited to binary terms like "coma" or "awake." These states can involve complex cognitive-motor dissociatio...

Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM Oliver A Cornely, Rosanne Sprute, Matteo Bassetti, et al Lancet Infect Dis 2025; 25: e280-e293 Summary Candida species are the predominant cause of fungal infections in patients treated in hospital, contributing substantially to morbidity and mortality. Candidaemia and other forms of invasive candidiasis primarily affect patients who ar...

Mycoplasma pneumoniae infection in adult inpatients during the 2023–24 outbreak in France (MYCADO): a national, retrospective, observational study Ariane Gavaud, Matthieu Holub, Antoine Asquier-Khati, et al Lancet Infect Dis Available online 19 February 2025 https://doi.org/10.1016/S1473-3099(24)00805-3 Summary Background An epidemic of Mycoplasma pneumoniae infection has been observed in France since September, 2023. We aimed to describe ...

Withdraw or Withhold Life-Sustaining Therapies in Patients With and Without Acute Brain Injury In ICU Tue, 18 Mar 2025 The decision to withdraw or withhold life-sustaining therapies (WLST) is a significant factor in many ICU deaths, influenced by patient factors such as age, comorbidities, illness severity, and patient or surrogate preferences. In patients with acute brain injuries (ABIs), WLST decisions may be particularly influenced by expectations o...

Invited Commentary  Health Policy February 19, 2025 Understanding and Addressing the US Hospital Bed Shortage—Build, Baby, Build Alexander T. Janke, Arjun K. Venkatesh JAMA Netw Open. 2025;8(2):e2460652. doi:10.1001/jamanetworkopen.2024.60652 For decades, policymakers have faced the impossible task of balancing concurrent and competing demands for high-quality, broadly accessible, and affordable hospital care. These demands have created th...

Perspective  AI in Medicine April 28, 2025 DeepSeek’s “Low-Cost” Adoption Across China’s Hospital Systems: Too Fast, Too Soon? Dian Zeng, Yiming Qin, Bin Sheng, et al JAMA. Published online April 28, 2025. doi:10.1001/jama.2025.6571 The large language models (LLMs) DeepSeek-V3 and DeepSeek-R1, developed by a subsidiary of a Chinese quantitative investment company, have the distinct advantages of being low...

Optimal Vasopressin Initiation in Septic Shock In Sepsis Tue, 18 Mar 2025 Sepsis is a common and potentially fatal condition, causing over 270,000 deaths annually in the U.S. Emergency treatment involves fluids and vasopressors, with norepinephrine as the first-line choice and vasopressin as a second-line option when blood pressure remains unresponsive. However, the timing of vasopressin use is unclear due to the dynamic nature of septic shock and limi...