Original Investigation July 28, 2020 Effect of Intravenous Acetaminophen on Postoperative Hypoxemia After Abdominal Surgery: The FACTOR Randomized Clinical Trial Alparslan Turan, Hani Essber,Wael Saasouh, et al JAMA. 2020;324(4):350-358. doi:10.1001/jama.2020.10009 Abstract Importance 背景 Opioid-induced ventilatory depression and hypoxemia is common, severe, and often unrecognized in postoperative patients. To the extent that nonopioid an...

ICU Management & Practice, Volume 20 - Issue 1, 2020 Nutrition for Critically Ill Patients with COVID-19 This article discusses the nutritional implications for critically ill patients admitted to intensive care for the management of COVID-19, and considers the inflammatory metabolic processes, nutrition-impacting symptoms, medical therapy, and the impact of a pandemic on staff resourcing and remote practice. Introduction The global pandemic caused by...

Research Letter July 14, 2020 Association Between Universal Masking in a Health Care System and SARS-CoV-2 Positivity Among Health Care Workers Xiaowen Wang, Enrico G. Ferro, Guohai Zhou, et al JAMA. Published online July 14, 2020. doi:10.1001/jama.2020.12897 The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has severely affected health care workers (HCWs).1 As a result, hos...

Imaging in Neurological Disease of Hospitalised COVID-19 Patients Originating in Wuhan, China, COVID-19 soon spread throughout the world and has been declared a pandemic by the World Health Organization. Italy was the second country to be hit as hard as China, with a total of 222,104 cases and 31,106 deaths (at time of publication). A study was conducted to understand the characteristics of neurological symptoms and neuroimaging features of COVID-19 patients admitte...

ICU Management & Practice, Volume 20 - Issue 1, 2020 Vasoactive Agent Management for Haemodynamic Support in COVID-19 Patients An overview of the Surviving Sepsis Guidelines for the vasoactive agent management of COVID-19 patients with septic shock and the use of arginine vasopressin in this patient population. The SARS-CoV-2 has caused a global health crisis. Thousands of people across the globe have been affected by COVID-19. Clinicians are in urgent n...

Reappraisal of Biomarkers in Sepsis Management Sepsis biomarkers have an important role in the diagnosis, prognosis, and treatment of sepsis management. If timely and accurate information about biomarkers becomes available, the physician can not only make better therapeutic choices but also monitor the efficacy of the intervention in progress and adjust it accordingly.   In a previous review published in 2010, researchers found 3370 references on 178 sepsi...

ARTICLES|ONLINE FIRST Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Geneva, Switzerland (SEROCoV-POP): a population-based study Silvia Stringhini, Ania Wisniak, Giovanni Piumatti, et al Lancet Published: June 11, 2020 DOI:https://doi.org/10.1016/S0140-6736(20)31304-0 Summary Background Assessing the burden of COVID-19 on the basis of medically attended case numbers is suboptimal given its reliance on testing strategy, changing case definitions, and...

Mechanical Ventilation in COVID-19 There is no specific treatment for COVID-19 patients. For those who develop respiratory failure and are unable to oxygenate with non-invasive methods, critical care doctors are providing supportive therapy. Since the pandemic started, mechanical ventilation has routinely been employed to oxygenate seriously ill COVID-19 patients. Each hospital has developed its own criteria for identifying patients who require mechanical ven...

Prone Positioning in Non-Intubated COVID-19 Patients The COVID-19 pandemic has placed unprecedented stress on health care institutions everywhere. Among other interventions, researchers and physicians have been trying to reevaluate the use of mechanical ventilation. The rise of social media has accelerated the spread of biased information about therapies that have not been peer-reviewed and have little to no evidence about its efficacy. Therefore, the question is wheth...

Original Investigation Caring for the Critically Ill PatientJune 4, 2020 Association of Noninvasive Oxygenation Strategies With All-Cause Mortality in Adults With Acute Hypoxemic Respiratory Failure: A Systematic Review and Meta-analysis Bruno L. Ferreyro, Federico Angriman, Laveena Munshi, et al JAMA. 2020;324(1):57-67. doi:10.1001/jama.2020.9524 Abstract Importance Treatment with noninvasive oxygenation strategie...