ONLINE FIRST (FREE ACCESS) STANDARD OF CARE IN THE INTENSIVE CARE UNIT Editorial Key principles and recent developments for ventilatory management of the surgical critically ill patientDe Jong, A., Jaber, S. & Schaefer, M. LATEST ARTICLES Conference Reports and Expert Panel European Society of Intensive Care Medicine Clinical Practice Guideline on fluid therapy in adult critically ill patients: Part 3—fluid removal at de-escalation phaseOstermann, M....

Original Investigation  Critical Care Medicine Early Blood Pressure Targets in Acute Spinal Cord Injury: A Randomized Clinical Trial Ruba Sajdeya, N. David Yanez, Michael Kampp, et al JAMA Netw Open 2025;8;(9):e2525364. doi:10.1001/jamanetworkopen.2025.25364 Key Points Question  Compared with conventional blood pressure, does early blood pressure augmentation improve long-term neurologic outcomes in acute spinal cord injury? Findings&nb...

Anti-Inflammatory Strategies for Sepsis-Induced Lung Injury In ICU Tue, 20 May 2025 ICU Management & Practice, Volume 25 - Issue 2, 2025 Sepsis-induced ARDS is a critical condition that may require anti-inflammatory strategies. There are some promising treatments that may alter the evolution, including corticosteroids, vitamin C, NET inhibitors, and statins, which help mitigate excessive immune response and improve clinical outcomes. Introdu...

Articles Benchmarking progress in non-communicable diseases: a global analysis of cause-specific mortality from 2001 to 2019 NCD Countdown 2030 Collaborators Lancet 2025; 406: 1255-1282 https://doi.org/10.1016/S0140-6736(25)01388-1 Summary Background Non-communicable diseases (NCDs) have received substantial policy attention globally and in most countries. Our aim was to quantify how much NCD mortality changed from 2010 to 2019 in different countries,...

JOURNAL ARTICLE A Clear and Present Danger: Encephalitis Due to Infection With Normocellular Cerebrospinal Fluid Karen Bloch,  Carol Glaser Clinical Infectious Diseases, Volume 81, Issue 1, 15 July 2025, Pages 188–189, https://doi.org/10.1093/cid/ciae387 Can encephalitis due to an infectious cause be present despite normocellular cerebral spinal fluid (CSF)? In the article “Absence of cerebrospinal fluid pleocytosis in encephalitis” by Habis et al, more than a...

Original Investigation  Equity, Diversity, and Inclusion Accuracy of Artificial Intelligence vs Professionally Translated Discharge Instructions Melissa Martos, Blanca Fields, Samuel G. Finlayson, et al JAMA Netw Open 2025;8;(9):e2532312. doi:10.1001/jamanetworkopen.2025.32312 Key Points Question  How does the accuracy of artificial intelligence (AI)–based translation compare with professional translation of discharge instructions under ro...

Statins Improve Clinical Outcomes in Patients With Sepsis In Sepsis Wed, 11 Jun 2025 Sepsis is a life-threatening condition that affects approximately 750,000 people annually in the U.S., with a mortality rate of around 27%. In about 15% of these cases, sepsis progresses to septic shock, a more severe state marked by dangerously low blood pressure and reduced tissue perfusion, where the risk of death increases to 30-40%. Prompt treatment significant...

JOURNAL ARTICLE EDITOR'S CHOICE Absence of Cerebrospinal Fluid Pleocytosis in Encephalitis Ralph Habis, Anna Kolchinski, Ashley N Heck, et al Clinical Infectious Diseases, Volume 81, Issue 1, 15 July 2025, Pages 179–187, https://doi.org/10.1093/cid/ciae391 Abstract Background Early diagnosis of encephalitis involves identifying signs of neuroinflammation, including cerebrospinal fluid (CSF) pleocytosis. However, an absence of CSF pleocytosis in ence...

Original Investigation  Postoperative Pulmonary Complications in Conventional Laparoscopic vs Robot-Assisted Abdominal Surgery Simon Corrado Serafini, Sabrine N. T. Hemmes, Verônica N. F. Queiroz, et al JAMA Surg Published Online: September 17, 2025 doi: 10.1001/jamasurg.2025.3581 Key Points Question  Is robotic-assisted surgery independently associated with higher incidence of postoperative pulmonary complications as compared with convent...

Evaluation of the impact of artificial intelligence-assisted image interpretation on the diagnostic performance of clinicians in identifying endotracheal tube position on plain chest X-ray: a multi-case multi-reader study  Alex Novak, Sarim Ather, Abdala T. Espinosa Morgado, et al Crit Care 2025; 29: 330 Abstract Background Incorrectly placed endotracheal tubes (ETTs) can lead to serious clinical harm. Studies have demonstrated the potential for artificial ...