JAMA Clinical Guidelines Synopsis March 26, 2020 Management of Critically Ill Adults With COVID-19 Jason T. Poston, Bhakti K. Patel, Andrew M. Davis JAMA. Published online March 26, 2020. doi:10.1001/jama.2020.4914 Guideline title Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults With COVID-19 Developer Surviving Sepsis Campaign (SSC) Release date March 23, 2020 Target population Critic...

Coronavirus and the Potential Role of ECMO The relatively new coronavirus has already infected thousands of patients in China and is now rapidly spreading globally. Many countries have already reported cases of coronavirus and the WHO has declared coronavirus disease 2019 (COVID-19) a public health emergency and has released preliminary guidelines on management of patients.  Most reports out of Wuhan, the epicenter of the outbreak, indicate that COVID-19 primarily a...

ONLINE FIRST (FREE ACCESS)  Conference Report and Expert Panel ~ Leoneet al. - Noninvasive respiratory support in the hypoxaemic peri-operative/periprocedural patient: a joint ESA/ESICM guideline Editorial ~Martin-Loeches I. et al. - Focus on infection Less is more in Intensive Care ~ Gattinoni L. et al.- “Less is More” in mechanical ventilation Original ~ De Weerdt A.et al. -  Pre-admi...

Allocating Ventilators in a Pandemic Life has come to a standstill as critical care doctors continue to battle COVID-19. The pandemic has led to shortages of essential goods and services - from hand sanitizers to masks to beds to ventilators. Today, the healthcare system is facing the prospect of rationing medical goods and services. Mechanical ventilation, in particular, has come out to be the most problematic. Several countries are already facing a shortage of ven...

Research: Severe burn injury alters intestinal microbiota composition and impairs intestinal barrier in mice 引用格式：Feng Y, Huang Y, Wang Y, Wang P, Wang F. Severe burn injury alters intestinal microbiota composition and impairs intestinal barrier in mice. Burns Trauma. 2019;7:20. 严重烧伤后应激反应所释放的神经内分泌介质、缺血缺氧性损害、活化补体、氧自由基、炎症介质、细胞因子等都可直接或间接地参与肠道屏障功能损害的发生与发展。肠道屏障功能损害一方面可以引起肠道自...

#CoronavirusOutbreak: Caring for the Critically Ill - Trends, Treatment and Mortality COVID-19 is associated with severe disease requiring intensive care in approximately 5% of proven infections. As with similar outbreaks in the past, including SARS, MERS, A(H7N9), and H1N1, critical care continues to be an integral component of the global response to Coronavirus. You might also like: Coronavirus and the Potential Role of ECMO Antiviral and/or immunomodulatory th...

Research Article: Prediction of median survival time in sepsis patients by the SOFA score combined with different predictors 引用格式: Li W, Wang M, Zhu B, Zhu Y, Xi X. Prediction of median survival time in sepsis patients by the SOFA score combined with different predictors. Burns Trauma. 2020, tkz006. 脓毒症和脓毒性休克是当今重症患者最具威胁性的疾病之一，具有较高的发病率和病死率。本研究旨在确定序贯器官衰竭评分（SOFA）、急性生理与慢性健康评分II（APACHE II）、降钙素...

HealthManagement, Volume 20 - Issue 2, 2020 COVID-19: What Can Healthcare Learn? Summary: A new decade is normally a time for optimism and fresh starts but what 2020 ushered in was a new coronavirus. Named by WHO as COVID-19, the virus causes severe acute respiratory problems. It is thought to have emerged at a live animal market in the Chinese city of Wuhan at the end of 2019 with an initial trickle of reports soon turning into a deluge as it spread across bor...

Editorial March 24, 2020 Infection, Antibiotics, and Patient Outcomes in the Intensive Care Unit Mo Yin, Paul Anantharajah Tambyah, Eli N. Perencevich JAMA. Published online March 24, 2020. doi:10.1001/jama.2020.2241 Infection is a major cause of admissions and prolonged stays in intensive care units (ICUs). Epidemiological information on the underlying source of infections, associated microorganisms, treatment, and eventual outcomes is essentia...

COVID-19: How Can Hospitals Protect Workers and Patients? The novel coronavirus COVID-19 continues its spread globally. Public authorities are implementing various measures to contain or delay it, from complete or partial territorial lockdowns to closing schools to banning larger public gatherings. In this situation healthcare systems are on the front line, and hospitals and healthcare leadership must take necessary steps to ensure the safety of their staff, ...