ONLINE FIRST (FREE ACCESS) LATEST ARTICLES OriginalVenous thromboembolism in critically ill adult patients with hematologic malignancy: a population-based cohort studyCarini F. C. et al. OPEN ACCESS ~ OriginalAcute kidney disease beyond day 7 after major surgery: a secondary analysis of the EPIS-AKI trialMeersch M. et al Long-term outcomes with haloperidol versus placebo in acutely admitted adult ICU patients with deliriumBekker Mortensen C. et al. Phase-3 ...

Research Letter  Equity, Diversity, and Inclusion January 11, 2024 Characteristics of Medical School Deans and University Hospital Directors in Japan Takashi Watari, Ashwin Gupta, Maika Hayashi, et al JAMA Netw Open. 2024;7(1):e2351526. doi:10.1001/jamanetworkopen.2023.51526 Introduction Medical school deans and university hospital directors are pivotal high-ranking leaders in health care organizations, exerting profound influence on th...

International Consensus Criteria for Paediatric Sepsis and Septic Shock In 2017, an estimated 25 million children worldwide experienced sepsis, resulting in over 3 million deaths. Paediatric sepsis survivors often face ongoing physical, cognitive, emotional, and psychological challenges. Children, particularly in lower-resource settings, face a higher risk of developing sepsis during their early years. The World Health Organization's resolution on sepsis underscore...

Original Investigation  Health Policy January 12, 2024 Vacation Days Taken, Work During Vacation, and Burnout Among US Physicians Christine A. Sinsky, Mickey T. Trockel, Lotte N. Dyrbye, et al JAMA Netw Open. 2024;7(1):e2351635. doi:10.1001/jamanetworkopen.2023.51635 Key Points Question  Are vacation days taken and working while on vacation associated with physician burnout? Findings  In this cross-sectional study...

Research Special Paper Publishers’ and journals’ instructions to authors on use of generative artificial intelligence in academic and scientific publishing: bibliometric analysis Conner Ganjavi, Michael B Eppler, Asli Pekcan, et al BMJ 2024; 384 doi: https://doi.org/10.1136/bmj-2023-077192 (Published 31 January 2024)Cite this as: BMJ 2024;384:e077192 Abstract Objectives To determine the extent and content of...

Research Letter  Pediatrics February 2, 2024 Interpretation of Antibiotic Trials in Pediatric Pneumonia Susan C. Lipsett, Alexander W. Hirsch, Richard G. Bachur, et al JAMA Netw Open. 2024;7(2):e2354470. doi:10.1001/jamanetworkopen.2023.54470 Introduction Recent randomized clinical trials have compared antibiotic regimens of varying intensity for the treatment of pediatric community-acquired pneumonia (CAP).1-4 These trials identif...

IMMUNOCITRE Trial - Enteral L-citrulline Administration vs Placebo Critically ill patients admitted to the ICU often experience temporary immune deficiencies, leading to persistent organ dysfunction and a higher risk of ICU-acquired infections. Researchers have been exploring immune-enhancing diets to address these issues, focusing on nutrients like L-arginine. L-arginine is important because it can become deficient in critically ill patients and is associated with...

CDC updates and simplifies respiratory virus recommendations Recommendations are easier to follow and help protect those most at risk CDC released today updated recommendations for how people can protect themselves and their communities from respiratory viruses, including COVID-19. The new guidance brings a unified approach to addressing risks from a range of common respiratory viral illnesses, such as COVID-19, flu, and RSV, which can cause significant he...

Original Investigation  Pediatrics February 2, 2024 Whole-Blood Gene Expression Profile After Hypoxic-Ischemic Encephalopathy Paolo Montaldo, Constance Burgod, Jethro A. Herberg, et al JAMA Netw Open. 2024;7(2):e2354433. doi:10.1001/jamanetworkopen.2023.54433 Key Points Question  Do genome expression profiles at birth in neonates with hypoxic-ischemic encephalopathy (HIE) in a high-income country (HIC) differ from those of the...

Knowledge and Awareness of Sepsis Among Risk Populations Sepsis can have potentially life-threatening consequences. Early recognition is crucial for effective intervention. The role of patients in preventing and identifying sepsis early is vital. However, there is an incomplete understanding of sepsis knowledge among at-risk groups and their ability to recognise sepsis as a medical emergency. COVID-19 often leads to sepsis, with about one-third of hospitalised C...