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Medscape Critical Care > Viewpoints COMMENTARY Global Patterns of ARDS Treatment Greg Martin, MD June 17, 2016 Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries Bellani G, Laffey JG, Pham T, et al; LUNG SAFE Investigators; ESICM Trials Group JAMA. 2016;23;315:788-800 Summary 总结 Acute respiratory distress syndrome (ARDS) is a form of acute inflammatory lung injury, most often due...
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Dynamic light application therapy to reduce the incidence and duration of delirium in intensive-care patients: A randomised controlled trial. ICM Index Number: 23/032 Authors: Simons KS, Laheij RJ, van den Boogaard M et al. Reference: Lancet Respir Med 2016;4:194–202. Trial registration number: NCT01274819. © Elsevier Ltd. ICM ABSTRACT Objective To investigate whether high-intensity dynamic light application (DLA) can reduce the incidence and/or duration of ICU-acquire...
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EDITORIAL DON'T EVER FORGET THE FOUR D's DURING FLUID THERAPY... Manu LNG Malbrain, MD, PhD Hospital Medical Director, ICU and High Care Burn Unit Director Ziekenhuis Netwerk Antwerpen, ZNA Stuivenberg Antwerp, Belgium The medical community only recently recognised the importance of fluids beyond their role for replacement, maintenance or haemodynamic stabilization and resuscitation. We should handle them the same as any other drug that we give to our patients [1-3]...
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Medscape Critical Care > Viewpoints  COMMENTARY Does Aspirin Reduce the Risk of Developing Acute Respiratory Distress Syndrome? Greg Martin, MD June 03, 2016 Effect of Aspirin on Development of ARDS in At-Risk Patients Presenting to the Emergency Department: The LIPS-A Randomized Clinical Trial Kor DJ, Carter RE, Park PK, et al; US Critical Illness and Injury Trials Group: Lung Injury Prevention with Aspirin Study Group (USCIITG: LIPS-A) JAMA. 2016 May 15. [Epub ahead o...
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Medscape Critical Care > Viewpoints  COMMENTARY Renal Replacement Therapy -- Sooner or Later? Greg Martin, MD June 06, 2016 Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit Gaudry S, Hajage D, Schortgen F, et al; AKIKI Study Group N Engl J Med. 2016 May 15. [Epub ahead of print] Summary 总结 Acute kidney injury (AKI) is a common and challenging condition to manage in critically ill patients, with many studies over the past decade attempting...
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Medscape Medical News > Conference News Early Treatment for Acute Kidney Injury Improves Outcomes Pam Harrison May 23, 2016 VIENNA — The initiation of renal replacement therapy less than 8 hours after the onset of stage 2 acute kidney injury significantly reduces all-cause mortality at 90 days, according to results from the ELAIN randomized clinical trial. 维也纳 — 根据ELAIN随机临床试验的结果,发生2级急性肾损伤后8小时内开始进行肾脏替代治疗,能够显著降低90天全因病死率。...
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Editorial Early to Dialyze: Healthy and Wise? Glenn M. Chertow, MD, MPH; Wolfgang C. Winkelmayer, MD, MPH, ScD JAMA. 2016;315(20):2190-2199. doi:10.1001/jama.2016.5828 Published online May 22, 2016. Acute kidney injury (AKI) among hospitalized patients is common, consequential, and costly. Annually in the United States, approximately 10% of the estimated 5 million hospitalizations are complicated by AKI, with 0.4% of cases severe enough to require dialysi...
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Editorial Renal-Replacement Therapy in the Critically Ill — Does Timing Matter? Ravindra L. Mehta, M.D., D.M. N Engl J Med 2016 DOI: 10.1056/NEJMe1606125 Deciding when to initiate renal-replacement therapy (hemodialysis, peritoneal dialysis, or continu- ous hemofiltration) in critically ill patients is challenging. Although there is wide acceptance that dialysis should be started in patients with end-stage renal disease when the glomerular filtration rate is 5 to...
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Conservative versus liberal oxygenation targets for mechanically ventilated patients – a pilot multicenter randomized controlled trial. ICM Index Number: 23/025 Authors: Panwar R, Hardie M, Bellomo R et al. Reference: Am J Respir Crit Care Med. 2016;193:43-51. Trial registration number: ACTRN12613000505707. © American Thoracic Society. ICM ABSTRACT Objective To determine whether conservative oxygen therapy is a feasible alternative to liberal oxygen therapy in ICU pati...
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