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【编者按】:近日,Intensive Care Medicine在线发表了华西医院ICU的研究结果。这一单中心RCT显示,ARDS患者早期使用APRV可显著缩短机械通气时间。在日前结束的欧洲重症医学年会(ESICM LIVES 2017)期间,华西医院的康焰教授作为来自中国大陆的唯一受邀讲者,介绍了这一研究的结果。 Early application of airway pressure release ventilation may reduce the duration of mechanical ventilation in acute respiratory distress syndrome. Zhou Y, Jin X, Lv Y, Wang P, Yang Y, Liang G, Wang B, Kang Y. Intens...
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RCTs and Guidelines (FREE ACCESS) Dear loyal ICM reader, We hope you enjoyed LIVES 2017 as much as we did! Whether you were able to join us live in Vienna for our special ICM sessions and critical trial presentations, or you viewed online, we are sure that you would agree that this amazing meeting offered plenty to guide practice, and inspire debate and future clinical research. We are proud to share several published papers from clinical trials presented at the congress ...
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News > Neurology No Benefit of Routine Oxygen in Acute Stroke Sue Hughes September 28, 2017 Routine use of prophylactic oxygen had no benefit or harm in a new large randomized trial in acute stroke patients. 一项新的有关急性卒中患者的大规模随机临床试验显示,常规进行预防性氧疗没有益处。 "This is the largest study of oxygen in acute stroke — the best data we have on this issue, and our results do not support the routine use of low-dose oxygen in nonhypoxic acute strok...
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Drugs & Diseases > Clinical Trends Clinical Trends for September 2017 Ryan Syrek September 29, 2017 Each week, we identify one top search term, speculate as to what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, feel free to share them with us on Twitter or Facebook! Clinical Trend of the Week (September 23-29): Medtronic An important, worldwide, voluntary recall resulted in this week'...
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ORIGINAL ARTICLE Age of Red Cells for Transfusion and Outcomes in Critically Ill Adults D. James Cooper, M.D., Zoe K. McQuilten, Ph.D., Alistair Nichol, Ph.D., Bridget Ady, M.Clin.Res.Meth., Cécile Aubron, Ph.D., Michael Bailey, Ph.D., Rinaldo Bellomo, M.D., Dashiell Gantner, M.B., B.S., David O. Irving, Ph.D., Kirsi-Maija Kaukonen, Ph.D., Colin McArthur, M.B., Ch.B., Lynne Murray, B.App.Sci., Ville Pettilä, Ph.D., and Craig French, M.B., B.S., for the TRANSFUSE Investigat...
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Original Investigation Caring for the Critically Ill Patient September 27, 2017 Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction Among High-Risk Patients Undergoing Major Surgery: A Randomized Clinical Trial Emmanuel Futier, Jean-Yves Lefrant, Pierre-Gregoire Guinot, et al. JAMA. Published online September 27, 2017. doi:10.1001/jama.2017.14172 Abstract Importance 背景 Perioperative hypotension is associat...
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Original Investigation September 26, 2017 Effect of Routine Low-Dose Oxygen Supplementation on Death and Disability in Adults With Acute Stroke: The Stroke Oxygen Study Randomized Clinical Trial Christine Roffe, Tracy Nevatte, Julius Sim, et al JAMA. 2017;318(12):1125-1135. doi:10.1001/jama.2017.11463 Importance 背景 Hypoxia is common in the first few days after acute stroke, is frequently intermittent, and is often undetected. Oxygen supplementation could prevent hypo...
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Original Investigation Caring for the Critically Ill Patient September 27, 2017 Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial Writing Group for the Alveolar Recruitment for Acute Respiratory Distress Syndrome Trial (ART) Investigators JAMA. Published online September 27, 2017. doi:10.1001/jama.2017.14171 Abstract Importance ...
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Original Investigation Caring for the Critically Ill Patient September 27, 2017 Effect of Systematic Intensive Care Unit Triage on Long-term Mortality Among Critically Ill Elderly Patients in France: A Randomized Clinical Trial Bertrand Guidet, Guillaume Leblanc, Tabassome Simon, et al JAMA. Published online September 27, 2017. doi:10.1001/jama.2017.13889  Abstract Importance 背景 The high mortality rate in critically ill elderly patients has led to questioning of...
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Original Investigation Caring for the Critically Ill Patient September 27, 2017 Effect of an Early Resuscitation Protocol on In-hospital Mortality Among Adults With Sepsis and HypotensionA Randomized Clinical Trial Ben Andrews, Matthew W. Semler, Levy Muchemwa, et al JAMA. Published online September 27, 2017. doi:10.1001/jama.2017.10913 Abstract Importance 背景 The effect of an early resuscitation protocol on sepsis outcomes in developing countries remains unknow...
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