COVID-19: How Can Hospitals Protect Workers and Patients? The novel coronavirus COVID-19 continues its spread globally. Public authorities are implementing various measures to contain or delay it, from complete or partial territorial lockdowns to closing schools to banning larger public gatherings. In this situation healthcare systems are on the front line, and hospitals and healthcare leadership must take necessary steps to ensure the safety of their staff, ...

Research Letter March 23, 2020 Ethics Committee Reviews of Applications for Research Studies at 1 Hospital in China During the 2019 Novel Coronavirus Epidemic Hui Zhang, Fengmin Shao, Jianqin Gu, et al JAMA. Published online March 23, 2020. doi:10.1001/jama.2020.4362 Since December 2019, an epidemic of coronavirus disease 2019 (COVID-19) has spread rapidly from Wuhan, Hubei Province, China.1 As of March 7, there were 1272 confirmed coronavirus c...

Original Investigation Prevalence and Outcomes of Infection Among Patients in Intensive Care Units in 2017 Jean-Louis Vincent, Yasser Sakr, Mervyn Singer, et al JAMA. Published online March 24, 2020. doi:10.1001/jama.2020.2717 Importance Infection is frequent among patients in the intensive care unit (ICU). Contemporary information about the types of infections, causative pathogens, and outcomes can aid the development of policies for prevention, diagnosis,...

JAMA Infographic February 26, 2020 Coronavirus Disease 2019 and Influenza 2019-2020 Edward Livingston, Karen Bucher, Andrew Rekito JAMA. 2020;323(12):1122. doi:10.1001/jama.2020.2633

Research Perioperative interventions for prevention of postoperative pulmonary complications: systematic review and meta-analysis Peter M Odor, Sohail Bampoe, David Gilhooly, et al BMJ 2020;368:m540 doi: https://doi.org/10.1136/bmj.m540   Abstract Objective To identify, appraise, and synthesise the best available evidence on the efficacy of perioperative interventions to reduce postoperative pulmonary complications (PPCs) in adult patients undergoing non...

JAMA Infographic March 17, 2020 Coronavirus Disease 2019 (COVID-19) in Italy Edward Livingston, Karen Bucher JAMA. Published online March 17, 2020. doi:10.1001/jama.2020.4344

Research Article: Neutralization of interleukin-17A alleviates burn-induced intestinal barrier disruption via reducing pro-inflammatory cytokines in a mouse model How to cite: Song Y, Li Y, Xiao Y, Hu W, Wang X, Wang P, et al. Burns Trauma.2019; 7:37. 烧伤后肠粘膜屏障受损可能由多种机制共同作用，其中，局部及全身炎症反应的参与是肠粘膜屏障功能受损的重要因素。因此，如何在烧伤早期有效控制炎症的发生、发展，是保护肠粘膜，减少并发症，改善预后的重要因素。在多种炎症疾病模型中...

Research Article: Timely completion of multiple life-saving interventions for traumatic haemorrhagic shock: a retrospective cohort study 引用格式: Mitra B, Bade-Boon J, Fitzgerald MC, Beck B, Cameron PA. Timely completion of multiple life-saving interventions for traumatic haemorrhagic shock: a retrospective cohort study. Burns Trauma. 2019; 7:22. Abstract Background Early control of haemorrhage and optimisation of physiology are guiding principles of resuscit...

Liberal or Conservative Oxygen Therapy for Acute Respiratory Distress Syndrome Loic Barrot, Pierre Asfar, Frederic Mauny, et al N Engl J Med 2020; 382:999-1008DOI: 10.1056/NEJMoa1916431 Abstract BACKGROUND In patients with acute respiratory distress syndrome (ARDS), the National Heart, Lung, and Blood Institute ARDS Clinical Trials Network recommends a target partial pressure of arterial oxygen (Pao2) between 55 and 80 mm Hg. Prospective validation of this ...

Effect of Reduced Exposure to Vasopressors on 90-Day Mortality in Older Critically Ill Patients With Vasodilatory Hypotension: A Randomized Clinical Trial François Lamontagne, Alvin Richards-Belle, Karen Thomas, et al JAMA. 2020;323(10):938-949. doi:10.1001/jama.2020.0930 Abstract Importance Vasopressors are commonly administered to intensive care unit (ICU) patients to raise blood pressure. Balancing risks and benefits of vasopressors is a challenge, parti...