ARTICLES|ONLINE FIRST Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study The NeuroVISION Investigators Lancet epub August 15, 2019 DOI:https://doi.org/10.1016/S0140-6736(19)31795-7 Summary Background 背景 In non-surgical settings, covert stroke is more common than overt stroke and is associated with cognitive decline. Although overt stroke occurs in less than 1% of adults after non-cardiac sur...

ARTICLES|ONLINE FIRST An artificial intelligence-enabled ECG algorithm for the identification of patients with atrial fibrillation during sinus rhythm: a retrospective analysis of outcome prediction Zachi I Attia, Peter A Noseworthy, Francisco Lopez-Jimenez, et al Lancet Published:August 01, 2019 DOI:https://doi.org/10.1016/S0140-6736(19)31721-0 Summary Background 背景 Atrial fibrillation is frequently asymptomatic and thus underdetected but is asso...

Letter | Published: 31 July 2019 A clinically applicable approach to continuous prediction of future acute kidney injury Nenad Tomašev, Xavier Glorot, Jack W. Rae, et al Nature  572, pages116–119 (2019) Abstract The early prediction of deterioration could have an important role in supporting healthcare professionals, as an estimated 11% of deaths in hospital follow a failure to promptly recognize and treat deteri...

ORIGINAL ARTICLE Transfusion Volume for Children with Severe Anemia in Africa Kathryn Maitland, Peter Olupot-Olupot, Sarah Kiguli, et al N Engl J Med 2019; 381:420-431DOI: 10.1056/NEJMoa1900100 Abstract BACKGROUND 背景 Severe anemia (hemoglobin level, <6 g per deciliter) is a leading cause of hospital admission and death in children in sub-Saharan Africa. The World Health Organization recommends transfusion of 20 ml of whole-blood equivalent per ...

Review August 13, 2019 Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications: A Review Daniel Brodie, Arthur S. Slutsky, Alain Combes JAMA. 2019;322(6):557-568. doi:10.1001/jama.2019.9302

ORIGINAL ARTICLE Immediate Transfusion in African Children with Uncomplicated Severe Anemia Kathryn Maitland, Sarah Kiguli, Peter Olupot-Olupot, et al. N Engl J Med 2019; 381:407-419DOI: 10.1056/NEJMoa1900105 Abstract BACKGROUND 背景 The World Health Organization recommends not performing transfusions in African children hospitalized for uncomplicated severe anemia (hemoglobin level of 4 to 6 g per deciliter and no signs of clinical severity). Howev...

Research Diagnosis of elevated intracranial pressure in critically ill adults: systematic review and meta-analysis Shannon M Fernando, Alexandre Tran, Wei Cheng, et al BMJ 2019;366:l4225 Abstract Objectives 背景 To summarise and compare the accuracy of physical examination, computed tomography (CT), sonography of the optic nerve sheath diameter (ONSD), and transcranial Doppler pulsatility index (TCD-PI) for the diagnosis of elevated intracranial pressure...

ORIGINAL ARTICLE A Multicenter Trial of Vena Cava Filters in Severely Injured Patients Kwok M. Ho, Sudhakar Rao, Stephen Honeybul, et al N Engl J Med 2019; 381:328-337DOI: 10.1056/NEJMoa1806515 Abstract BACKGROUND 背景 Whether early placement of an inferior vena cava filter reduces the risk of pulmonary embolism or death in severely injured patients who have a contraindication to prophylactic anticoagulation is not known. 对于具有预防性抗凝禁忌的严重...

Original Investigation | July 23/30, 2019 Intensive vs Standard Treatment of Hyperglycemia and Functional Outcome in Patients With Acute Ischemic Stroke: The SHINE Randomized Clinical Trial Karen C. Johnston, Askiel Bruno, Qi Pauls, et al JAMA. 2019;322(4):326-335. doi:10.1001/jama.2019.9346 Abstract Importance 背景 Hyperglycemia during acute ischemic stroke is common and is associated with worse out...

Original Investigation  Association Between State-Mandated Protocolized Sepsis Care and In-hospital Mortality Among Adults With Sepsis Jeremy M. Kahn, Billie S. Davis, Jonathan G. Yabes, et al JAMA. 2019;322(3):240-250. doi:10.1001/jama.2019.9021 Abstract Importance 背景 Beginning in 2013, New York State implemented regulations mandating that hospitals implement evidence-based protocols for sepsis management, ...