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Original Investigation March 4, 2021 Effect of Ivermectin on Time to Resolution of Symptoms Among Adults With Mild COVID-19: A Randomized Clinical Trial Eduardo López-Medina, Pío López, Isabel C. Hurtado, et al JAMA. Published online March 4, 2021. doi:10.1001/jama.2021.3071 Abstract Importance Ivermectin is widely prescribed as a potential treatment for COVID-19 despite uncertainty about its clinical benefit. Objective To determine ...
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Research Excess mortality in Wuhan city and other parts of China during the three months of the covid-19 outbreak: findings from nationwide mortality registries Jiangmei Liu, Lan Zhang,  Yaqiong Yan, et al BMJ 2021; 372: n415 doi: https://doi.org/10.1136/bmj.n415 (Published 24 February 2021) Abstract Objective To assess excess all cause and cause specific mortality during the three months (1 January to 31 March 2020) of the coronavirus disease 2019 (covi...
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Research Letter February 17, 2021 Discriminant Accuracy of the SOFA Score for Determining the Probable Mortality of Patients With COVID-19 Pneumonia Requiring Mechanical Ventilation Robert A. Raschke, Sumit Agarwal, Pooja Rangan, et al JAMA. Published online February 17, 2021. doi:10.1001/jama.2021.1545 The coronavirus disease 2019 (COVID-19) pandemic has raised concern regarding the capacity to provide care for a surge of critically ill patient...
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ARTICLES|ONLINE FIRST Azithromycin for community treatment of suspected COVID-19 in people at increased risk of an adverse clinical course in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial PRINCIPLE Trial Collaborative Group Lancet Published:March 04, 2021 DOI:https://doi.org/10.1016/S0140-6736(21)00461-X Summary Background Azithromycin, an antibiotic with potential antiviral and anti-inflammatory properties, has b...
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HOW TO VENTILATE COVID-19 PATIENTS? TWINSTREAM® ICU WITH P-BLV® (PULSATILE BILEVEL VENTILATION) The Austrian critical care ventilator TwinStream® ICU was designed with the explicit purpose of saving critically respiratory-distressed patients. In particular those patients with severe lung diseases (e.g. ARDS) who can no longer be supported with conventional ventilation. Its unique p-BLV® mode has become an established value in many Intensive Care Units in Austrian...
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ARTICLES|ONLINE FIRST Identification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19: a multicentre cohort study Belén Gutiérrez-Gutiérrez, María Dolores del Toro, Alberto M Borobia, et al Lancet Infect Dis Published:February 23, 2021 DOI:https://doi.org/10.1016/S1473-3099(21)00019-0 Summary Background The clinical presentation of COVID-19 in patients admitted to hospital is heterogen...
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Research High flow oxygen and risk of mortality in patients with a suspected acute coronary syndrome: pragmatic, cluster randomised, crossover trial Ralph A H Stewart, Peter Jones, Bridget Dicker, et al BMJ 2021; 372: n355 doi: https://doi.org/10.1136/bmj.n355 (Published 02 March 2021) Abstract Objective To determine the association between high flow supplementary oxygen and 30 day mortality in patients presenting with a suspected acute coronary syndrome...
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Explore the most influential publications by Chinese researchers We are proud to present a selection of the latest high-impact publications* in clinical medicine by Chinese researchers across from Springer Nature. We hope you enjoy reading this selection and find it helpful.  * High-impact publications in their academic fields as of 2020, according to SN Insights. Open access articles are freely available online on a permanent basis. A pneumonia...
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Original Investigation March 18, 2021 Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit: The INSPIRATION Randomized Clinical Trial INSPIRATION Investigators JAMA. Published online March 18, 2021. doi:10.1001/jama.2021.4152 Abstract Importance 背景 Thrombotic events are co...
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ONLINE FIRST THIS WEEK(FREE ACCESS) Letter ~ Rousset D. et al. - Bedside ultrasound monitoring of prone position induced lung inflationCOVID-19 in Intensive Care ~ Sandroni C. et al. ~The impact of COVID-19 on the epidemiology, outcome and management of cardiac arrestConference Reports and Expert Panel ~ Domínguez-Gil B. et al. - Expanding controlled donation after the circulatory determination of death: statement from an international collaborativeCOVID-19 in Intensiv...
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