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EDITORIAL Finding the Right Balance Birgitte Brandstrup N Engl J Med 2018; 378:2335-2336 DOI: 10.1056/NEJMe1805615 When I was a young resident in the 1990s, surgical patients received so much intravenous saline on the day of surgery that they often gained 4 to 6 kg, and by postoperative day 2 or 3, pulmonary congestion and cardiac arrhythmias were commonplace. That was the basis for a 2003 trial of restrictive versus standard fluid therapy,1 which aimed to answer a simple ...
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Intensive Care Medicine ONLINE FIRST THIS WEEK (FREE ACCESS) Editorial debate ~ ​Jean-François Timsit and Matteo Bassett. Antipathy against SDD is justified: Yes. Editorial debate ~ Luciano Silvestri et al. Antipathy against SDD is justified: No. ​ Editorial debate ~ Michael Quintel et al. Antipathy against SDD is justified: We are not sure. Original ~ Elie Azoulay et al. Management and outcomes of acute respiratory distress syndrome patients with and without comorbid cond...
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News > WebMD Health News Vitamin Cocktail for Sepsis Getting Wider Test Matt Smith May 29, 2018 A simple vitamin cocktail to treat sepsis has shaken up the medical world, raising hopes of a more effective treatment for one of history's great killers. But will it stand up to tougher tests? 一种简单的维生素鸡尾酒疗法治疗全身性感染对医学界产生了震动,为治疗这种一个世纪以来危及生命的临床疾病带来了有效治疗的曙光。但是,这种疗法能否经受更加严苛的验证呢? Researchers at sev...
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Editorial May 20, 2018 qSOFA Score for Patients With Sepsis in Low- and Middle-Income Countries Neill K. J. Adhikari, Gordon D. Rubenfeld JAMA. Published online May 20, 2018. doi:10.1001/jama.2018.6413 In the past 2 years, sepsis has received considerable attention from the global community. In 2017, the World Health Assembly passed a resolution urging all 194 UN Member States to implement actions to reduce the burden of sepsis, and for the World Health Organization to...
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CORRESPONDENCE ICU Admissions for Sepsis or Pneumonia in Australia and New Zealand in 2017 Aidan Burrell, Sue Huckson, David V. Pilcher for the ANZICS N Engl J Med 2018; 378:2138-2139 DOI: 10.1056/NEJMc1717178 TO THE EDITOR: Seasonal patterns of presentations to intensive care units (ICUs) in the Southern Hemisphere can inform health care planning for critically ill patients worldwide, as was seen during the H1N1 influenza pandemic in 2009.1 During the late winter and earl...
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Original Investigation May 20, 2018 Association of the Quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA) Score With Excess Hospital Mortality in Adults With Suspected Infection in Low- and Middle-Income Countries Kristina E. Rudd, Christopher W. Seymour, Adam R. Aluisio, et al JAMA. Published online May 20, 2018. doi:10.1001/jama.2018.6229 Abstract Importance 背景 The quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA) score has not be...
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Medical News & Perspectives May 22/29, 2018 Taking a Closer Look at the Biomarker Test for Mild Traumatic Brain Injury Rebecca Voelker, MSJ JAMA. 2018;319(20):2066-2067. doi:10.1001/jama.2018.4644 Not long after a first-of-its-kind blood test received approval to evaluate patients with mild traumatic brain injury, headlines dubbed it a “concussion test.” But experts in biomarkers are clarifying certain misconceptions about what the test can and can’t reveal. “It’s ...
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Original Investigation June 5, 2018 Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration Lisa M. Askie, Brian A. Darlow, Neil Finer, et al. JAMA. 2018;319(21):2190-2201. doi:10.1001/jama.2018.5725 Abstract Importance 背景 There are potential benefits and harms of hyperoxemia and hypoxemia for extremely preterm infants receiving more vs less supplemental...
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Intensive Care Medicine ONLINE FIRST THIS WEEK (FREE ACCESS) What's New in Intensive Care ~ R. T. Mankowski et al. Long-term impact of sepsis on cardiovascular health. Original ~ Mieke Deschepper et al. Effects of chlorhexidine gluconate oral care on hospital mortality: a hospital-wide, observational cohort study. Review ~ Antoine Vieillard-Baron et al. Diagnostic workup, etiologies and management of acute right ventricle failure. Review ~ Spyros D. Mentzelopoulos et al....
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Original Investigation May 8, 2018 Association of Vasopressin Plus Catecholamine Vasopressors vs Catecholamines Alone With Atrial Fibrillation in Patients With Distributive Shock: A Systematic Review and Meta-analysis William F. McIntyre, Kevin J. Um, Waleed Alhazzani, et al JAMA. 2018;319(18):1889-1900. doi:10.1001/jama.2018.4528 Abstract Importance Vasopressin is an alternative to catecholamine vasopressors for patients with distributive shock—a condition due to ex...
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