ARTICLES|ONLINE FIRST Conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU): a UK multicentre, open, parallel-group, randomised clinical trial Mark J Peters, Doug W Gould, Samiran Ray, et al Lancet Published:December 01, 2023 DOI: https://doi.org/10.1016/S0140-6736(23)01968-2 Summary Background The optimal target for systemic oxygenation in critically ill children is unknown. Liberal oxygenation is widely practiced, bu...

Original Investigation  November 15, 2023 Demographic Representation in 3 Leading Artificial Intelligence Text-to-Image Generators Rohaid Ali, Oliver Y. Tang, Ian D. Connolly, et al JAMA Surg. Published online November 15, 2023. doi:10.1001/jamasurg.2023.5695 Key Points Question  How accurate are 3 leading artificial intelligence (AI) text-to-image generators at representing demographic realitie...

Original Investigation  November 15, 2023 Transforming Team Performance Through Reimplementation of the Surgical Safety Checklist James C. Etheridge, Rachel Moyal-Smith, Tze Tein Yong, et al JAMA Surg. Published online November 15, 2023. doi:10.1001/jamasurg.2023.5400 Key Points Question  Can a systematic approach to reimplementation of an underperforming surgical safety checklist improve team behavior and performance? Finding...

ARTICLES|ONLINE FIRST Clinical descriptors of disease trajectories in patients with traumatic brain injury in the intensive care unit (CENTER-TBI): a multicentre observational cohort study Cecilia A I Åkerlund, Anders Holst, Shubhayu Bhattacharyay, et al. Lancet Neurol Published: November 14, 2023 DOI:https://doi.org/10.1016/S1474-4422(23)00358-7 Summary Background Patients with traumatic brain injury are a heterogeneous population, and the most sever...

Original Investigation  November 15, 2023 Operative vs Nonoperative Management of Acute Cholecystitis During the Different Trimesters of Pregnancy Mariam N. Hantouli, David J. Droullard, Michael G. Nash, et al JAMA Surg. Published online November 15, 2023. doi:10.1001/jamasurg.2023.5803 Key Points Question  For pregnant patients presenting with acute cholecystitis (AC), is there a difference in adverse outcomes between those who ...

Research Christmas 2023: Marginal Gains Common Healthcare Related Instruments Subjected To Magnetic Attraction Study (CHRISTMAS): prospective in situ experimental study Shao J Ong, Koon Liang Chia, Teik Choon See, et al BMJ 2023; 383 doi: https://doi.org/10.1136/bmj-2023-077164 (Published 21 December 2023)Cite this as: BMJ 2023;383:e077164 Abstract Objective To investigate the behaviour of common healthcare ...

Research Christmas 2023: Champagne problems Association of health benefits and harms of Christmas dessert ingredients in recipes from The Great British Bake Off: umbrella review of umbrella reviews of meta-analyses of observational studies Joshua D Wallach, Anant Gautam, Reshma Ramachandran, et al BMJ 2023; 383 doi: https://doi.org/10.1136/bmj-2023-077166 (Published 20 December 2023)Cite this as: BMJ 2023;383:e077166 Abstract Objective To determin...

ARTICLES|ONLINE FIRST Oral VV116 versus placebo in patients with mild-to-moderate COVID-19 in China: a multicentre, double-blind, phase 3, randomised controlled study Xiaohong Fan, Xiahong Dai, Yun Ling, et al. Lancet Infect Dis Published: November 22, 2023 DOI:https://doi.org/10.1016/S1473-3099(23)00577-7 Summary Background Spread of SARS-CoV-2 led to a global pandemic, and there remains unmet medical needs in the treatment of Omicron infections. VV1...

Feature Christmas 2023: Champagne Problems Cheers not tears: champagne corks and eye injury Ethan Waisberg, Joshua Ong, Mouayad Masalkhi, et al BMJ 2023; 383 doi: https://doi.org/10.1136/bmj.p2520 (Published 20 December 2023)Cite this as: BMJ 2023;383:p2520 Be careful this holiday season: ocular trauma while opening bottles of fizz can be significant—and easily avoided, advise Ethan Waisberg and colleagues The joyful effervescence of champagne is ...

Research Christmas 2023: Annual leave Retail demand for emergency contraception in United States following New Year holiday: time series study Brandon Wagner, Kelly Cleland BMJ 2023; 383 doi: https://doi.org/10.1136/bmj-2023-077437 (Published 20 December 2023)Cite this as: BMJ 2023;383:e077437 Abstract Objective To estimate the increase in sales of emergency contraception following the New Year’s Eve/New Year’s Day holiday. Design Time ser...