The Minnesota Medical Operations Coordination Center: A COVID-19 Statewide Response to Ensure Access to Critical Care and Medical-Surgical Beds Karyn D. Baum, Lauren Vlaanderen, Walter James, et al Chest 2024; 165: 95-109 Background COVID-19 led to unprecedented inpatient capacity challenges, particularly in ICUs, which spurred development of statewide or regional placement centers for coordinating transfer (load-balancing) of adult patients needing intensive ...

ONLINE FIRST (FREE ACCESS) TOP 6 MOST CITED ARTICLES IN 2023 OriginalEchocardiography phenotypes of right ventricular involvement in COVID-19 ARDS patients and ICU mortality: post-hoc (exploratory) analysis of repeated data from the ECHO-COVID studyHuang S. et al. Direct assessment of microcirculation in shock: a randomized-controlled multicenter studyRomano Bruno R. et al. Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care...

ORIGINAL ARTICLE Skin Antisepsis before Surgical Fixation of Extremity Fractures The PREP-IT Investigators N Engl J Med 2024; 390:409-420DOI: 10.1056/NEJMoa2307679 BACKGROUND Studies evaluating surgical-site infection have had conflicting results with respect to the use of alcohol solutions containing iodine povacrylex or chlorhexidine gluconate as skin antisepsis before surgery to repair a fractured limb (i.e., an extremity fracture). METHODS In a cl...

CHEST INFECTIONS: ORIGINAL RESEARCH| VOLUME 165, ISSUE 1, P68-78, JANUARY 2024 Comparative Effectiveness of First-Line and Alternative Antibiotic Regimens in Hospitalized Patients With Nonsevere Community-Acquired Pneumonia: A Multicenter Retrospective Cohort Study Anthony D. Bai, Siddhartha Srivastava, Benjamin K.C. Wong, et al Chest 2024; 165: 68-78 Published: August 10, 2023 DOI: https://doi.org/10.1016/j.chest.2023.08.008 Background There are several...

Research Letter  Health Care Policy and Law January 2, 2024 Automated External Defibrillator Use After Out-of-Hospital Cardiac Arrest at Recreational Facilities Ahmed A. Kolkailah, Paul S. Chan, Qiang Li, et al JAMA Intern Med. Published online January 2, 2024. doi:10.1001/jamainternmed.2023.7248 Out-of-hospital cardiac arrest (OHCA) during exercise is often due to a ventricular arrhythmia for which prompt defibrillation from an automated ...

ARTICLES| VOLUME 24, ISSUE 1, P36-45, JANUARY 2024 Antiviral efficacy of molnupiravir versus ritonavir-boosted nirmatrelvir in patients with early symptomatic COVID-19 (PLATCOV): an open-label, phase 2, randomised, controlled, adaptive trial William H K Schilling, Podjanee Jittamala, James A Watson, et al Lancet Infect Dis 2024; 24: 36-45 DOI:https://doi.org/10.1016/S1473-3099(23)00493-0 Summary Background Molnupiravir and ritonavir-boosted nirmatrelv...

Original Investigation  November 22, 2023 Risk of Mortality Following Surgery in Patients With a Previous Cardiovascular Event Christos V. Chalitsios, Matthew S. Luney, William A. Lindsay, et al JAMA Surg. Published online November 22, 2023. doi:10.1001/jamasurg.2023.5951 Key Points Question  Is the time elapsed since a cardiovascular event associated with an increased risk of mortality in patie...

Original Investigation  December 20, 2023 Preoperative Midazolam and Patient-Centered Outcomes of Older Patients: The I-PROMOTE Randomized Clinical Trial Ana Kowark, András P. Keszei, Gerhard Schneider, et al JAMA Surg. Published online December 20, 2023. doi:10.1001/jamasurg.2023.6479 Key Points Question  Is global perioperative patient satisfaction different in older patients administered preo...

Research Letter  December 27, 2023 Affiliation Bias in Peer Review of Abstracts by a Large Language Model Dario von Wedel; Rico A. Schmitt; Moritz Thiele; et al JAMA. Published online December 27, 2023. doi:10.1001/jama.2023.24641 Ever-increasing numbers of submitted manuscripts put the academic publishing system and its human peer reviewers under pressure.1 Researchers have started to use large language models (LLMs) as support for writ...

Original Investigation  December 26, 2023 Changes in Hospital Adverse Events and Patient Outcomes Associated With Private Equity Acquisition Sneha Kannan, Joseph Dov Bruch, Zirui Song JAMA. 2023;330(24):2365-2375. doi:10.1001/jama.2023.23147 Key Points Question  How do quality of care and patient outcomes change after private equity acquisition of hospitals? Findings  In a difference-in-differences examination of 662...