ARTICLES|ONLINE FIRST Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 GBD 2021 Diseases and Injuries Collaborators Lancet Open Access Published: April 17, 2024 DOI: https://doi.org/10.1016/S0140-6736(...

Research Predicting the risks of kidney failure and death in adults with moderate to severe chronic kidney disease: multinational, longitudinal, population based, cohort study Ping Liu, Simon Sawhney, Uffe Heide-Jørgensen, et al BMJ 2024; 385 doi: https://doi.org/10.1136/bmj-2023-078063 (Published 15 April 2024)Cite this as: BMJ 2024;385:e078063 Abstract Objective To train and test a super learner strategy for ri...

Original Investigation  June 10, 2024 Electroencephalography-Guided Anesthesia and Delirium in Older Adults After Cardiac Surgery: The ENGAGES-Canada Randomized Clinical Trial Alain Deschamps, Arbi Ben Abdallah, Eric Jacobsohn, et al JAMA. Published online June 10, 2024. doi:10.1001/jama.2024.8144 Key Points Question  Does electroencephalography-guided anesthetic administration to minimize elect...

Research Letter  February 21, 2024 Electric Bicycle Injuries and Hospitalizations Adrian M. Fernandez, Kevin D. Li, Hiren V. Patel, et al JAMA Surg. 2024;159(5):586-588. doi:10.1001/jamasurg.2023.7860 Electric bicycles (e-bicycles) are a popular consumer choice in the clean transportation revolution. Imports of e-bicycles topped 1.1 million in 2022 compared with 437 000 in 2020.1 We examined e-bicycle injuries and hospitalizations in the US fro...

Original Investigation  February 21, 2024 Intraoperative Wound Irrigation for the Prevention of Surgical Site Infection After Laparotomy: A Randomized Clinical Trial by CHIR-Net Tara Catharina Mueller, Victoria Kehl, Rebekka Dimpel, et al JAMA Surg. 2024;159(5):484-492. doi:10.1001/jamasurg.2023.7985 Key Points Question  Is prophylactic intraoperative wound irrigation with polyhexanide 0.04% solution e...

Original Investigation  March 6, 2024 Robotic Technology in Emergency General Surgery Cases in the Era of Minimally Invasive Surgery Nicole Lunardi, Aida Abou-Zamzam, Katherine L. Florecki, et al JAMA Surg. 2024;159(5):493-499. doi:10.1001/jamasurg.2024.0016 Key Points Question  Do outcomes for emergency general surgery vary by surgical approach? Findings  In this cohort study of more than 1 ...

Original Investigation  June 3, 2024 Jinlida for Diabetes Prevention in Impaired Glucose Tolerance and Multiple Metabolic Abnormalities: The FOCUS Randomized Clinical Trial Hangyu Ji, Xuefei Zhao, Xinyan Chen, et al JAMA Intern Med. Published online June 3, 2024. doi:10.1001/jamainternmed.2024.1190 Key Points Question  Can long-term use of Jinlida granules (JLD) reduce the incidence of diabetes ...

Original Investigation  June 5, 2024 Large Language Model Capabilities in Perioperative Risk Prediction and Prognostication Philip Chung, Christine T. Fong, Andrew M. Walters, et al JAMA Surg. Published online June 5, 2024. doi:10.1001/jamasurg.2024.1621 Key Points Question  Can a large language model perform risk stratification and predict postoperative outcome measures using a description of t...

Original Investigation  April 15, 2024 Acute Cardiac Events in Hospitalized Older Adults With Respiratory Syncytial Virus Infection Rebecca C. Woodruff, Michael Melgar, Huong Pham, et al JAMA Intern Med. 2024;184(6):602-611. doi:10.1001/jamainternmed.2024.0212 Key Points Question  What are the frequency and severity of acute cardiac events among hospitalized adults aged 50 years or older with laboratory-c...

Original Investigation  June 7, 2024 Nirmatrelvir-Ritonavir and Symptoms in Adults With Postacute Sequelae of SARS-CoV-2 Infection: The STOP-PASC Randomized Clinical Trial Linda N. Geng, Hector Bonilla, Haley Hedlin, et al JAMA Intern Med. Published online June 7, 2024. doi:10.1001/jamainternmed.2024.2007 Key Points Question  What is the efficacy of 15 days of nirmatrelvir-ritonavir for improvin...