Twenty percent human albumin solution fluid bolus administration therapy in patients after cardiac surgery-II: a multicentre randomised controlled trial Wigmore, G.J., Deane, A.M., Presneill, J.J. et al. Intensive Care Med 50, 1075–1085 (2024) https://doi.org/10.1007/s00134-024-07488-3 Abstract Purpose After cardiac surgery, fluid bolus therapy (FBT) with 20% human albumin may facilitate less fluid and vasopressor administration than FBT with crystalloid...

Calcium supplementation during trauma resuscitation: a propensity score-matched analysis from the TraumaRegister DGU® Dries Helsloot, Mark Fitzgerald, Rolf Lefering, et al Critical Care volume 28, Article number: 222 (2024) Abstract Background In major trauma patients, hypocalcemia is associated with increased mortality. Despite the absence of strong evidence on causality, early calcium supplementation has been recommended. This study investigates whether c...

Original Investigation  Critical Care Medicine July 12, 2024 Barriers, Solutions, and Opportunities for Adapting Critical Care Clinical Trials in the COVID-19 Pandemic Deborah Cook, Shipra Taneja, Karla Krewulak, et al JAMA Netw Open. 2024;7(7):e2420458. doi:10.1001/jamanetworkopen.2024.20458 Key Points Question  What barriers, solutions, and opportunities were associated with continuing crit...

Original Investigation  Pharmacy and Clinical Pharmacology July 9, 2024 Agreement of Different Drug-Drug Interaction Checkers for Proton Pump Inhibitors Massimo Carollo, Salvatore Crisafulli, Margherita Selleri, et al JAMA Netw Open. 2024;7(7):e2419851. doi:10.1001/jamanetworkopen.2024.19851 Key Points Question  What is the level of agreement between the summary of product characteristics (SP...

Original Investigation  July 10, 2024 Prehospital Partial Resuscitative Endovascular Balloon Occlusion of the Aorta for Exsanguinating Subdiaphragmatic Hemorrhage Robbie A. Lendrum, Zane Perkins, Max Marsden, et al JAMA Surg. Published online July 10, 2024. doi:10.1001/jamasurg.2024.2254 Key Points Question  Is it feasible to deploy prehospital zone 1 (supraceliac) partial resuscitative endovasc...

Original Investigation  Pediatrics July 5, 2024 Probiotics and Antibiotic-Induced Microbial Aberrations in Children: A Secondary Analysis of a Randomized Clinical Trial Thomas H. Dierikx, Anna M. Malinowska, Jan Łukasik, et al JAMA Netw Open. 2024;7(7):e2418129. doi:10.1001/jamanetworkopen.2024.18129 Key Points Question  What is the effect of a multispecies probiotic on antibiotic-induced gut...

Original Investigation  May 8, 2024 Decision-Making Confidence of Clinical Competency Committees for Entrustable Professional Activities Kelsey B. Montgomery, John D. Mellinger, M. Chandler McLeod, et al JAMA Surg. 2024;159(7):801-808. doi:10.1001/jamasurg.2024.0809 Key Points Question  What factors are associated with variation in decision-making confidence of clinical competency committees (CCCs) for su...

Original Investigation  Public Health July 12, 2024 COVID-19 Pandemic Quarantines and Mental Health Among Adolescents in Norway Johanne H. Pettersen, Laurie J. Hannigan, Kristin Gustavson, et al JAMA Netw Open. 2024;7(7):e2422189. doi:10.1001/jamanetworkopen.2024.22189 Key Points Question  How were stringent public health measures and quarantine during the COVID-19 pandemic associated with me...

Original Investigation  Statistics and Research Methods July 8, 2024 Performance of a Large Language Model in Screening Citations Takehiko Oami, Yohei Okada, Taka-aki Nakada JAMA Netw Open. 2024;7(7):e2420496. doi:10.1001/jamanetworkopen.2024.20496 Key Points Question  How accurate and efficient is a large language model (LLM) for screening titles and abstracts for article inclusion in a systemati...

Original Investigation  Public Health July 10, 2024 Feedback and Financial Incentives for Reducing Cell Phone Use While Driving: A Randomized Clinical Trial M. Kit Delgado, Jeffrey P. Ebert, Ruiying A. Xiong, et al JAMA Netw Open. 2024;7(7):e2420218. doi:10.1001/jamanetworkopen.2024.20218 Key Points Question  Can behavioral interventions decrease handheld cell phone–based driver distraction? ...