ONLINE FIRST (FREE ACCESS) LATEST ARTICLES OPEN ACCESS ~ OriginalTwenty percent human albumin solution fluid bolus administration therapy in patients after cardiac surgery-II: a multicentre randomised controlled trialWigmore G. J. et al Lower or higher oxygenation targets in the intensive care unit: an individual patient data meta-analysis Mølgaard Nielsen F. et al EditorialThe limitations of evidence-based medicine compel the practice of personalized ...

Original Investigation  Surgery August 2, 2024 Surgical Repair vs Splenectomy in Patients With Severe Traumatic Spleen Injuries Dominik A. Jakob, Martin Müller, Apostolos Kolitsas, et al JAMA Netw Open. 2024;7(8):e2425300. doi:10.1001/jamanetworkopen.2024.25300 Key Points Question  Is splenic repair associated with better outcomes compared with splenectomy in patients with traumatic splenic i...

Original Investigation  June 27, 2024 A More Selective vs a Standard Risk-Stratified, Heparin-Based, Obstetric Thromboprophylaxis Protocol Macie L. Champion, Christina T. Blanchard, Michelle Y. Lu, et al JAMA. 2024;332(4):310-317. doi:10.1001/jama.2024.8684 Key Points Question  Among patients with increased risk of postpartum venous thromboembolism, does a more selective protocol for initiating postpartum...

Original Investigation  July 31, 2024 Venous Thromboembolism Prophylaxis in High-Risk Pediatric Trauma Patients Amanda B. Witte, Kyle Van Arendonk, Carisa Bergner, et al JAMA Surg. Published online July 31, 2024. doi:10.1001/jamasurg.2024.2487 Key Points Question  Does the application of high-risk guidelines allow for safe and appropriate administration of venous thromboembolism (VTE) prophylaxi...

Research Personal protective effect of wearing surgical face masks in public spaces on self-reported respiratory symptoms in adults: pragmatic randomised superiority trial Runar Barstad Solberg, Atle Fretheim, Ingeborg Hess Elgersma, et ak BMJ 2024; 386 doi: https://doi.org/10.1136/bmj-2023-078918 (Published 24 July 2024) Cite this as: BMJ 2024;386:e078918 Abstract Objective To evaluate the personal protective effects of wearing versus not wearing s...

ONLINE FIRST (FREE ACCESS) LATEST ARTICLES OriginalThrombolysis before venoarterial ECMO for high-risk pulmonary embolism: a retrospective cohort studyLevy D. et al Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: a stepped wedge cluster randomized clinical trialFreund Y. et al OPEN ACCESS ~ OriginalStandardised and automated assessment of head computed tomography reliably predicts poor functional outcome aft...

Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: a stepped wedge cluster randomized clinical trial Freund, Y., de Abreu, M.C., Lebal, S. et al. Intensive Care Med 50, 1086–1095 (2024). https://doi.org/10.1007/s00134-024-07509-1 Abstract Purpose The efficacy of the 1-h bundle for emergency department (ED) patients with suspected sepsis, which includes lactate measurement, blood culture, broad-spectrum an...

Twenty percent human albumin solution fluid bolus administration therapy in patients after cardiac surgery-II: a multicentre randomised controlled trial Wigmore, G.J., Deane, A.M., Presneill, J.J. et al. Intensive Care Med 50, 1075–1085 (2024) https://doi.org/10.1007/s00134-024-07488-3 Abstract Purpose After cardiac surgery, fluid bolus therapy (FBT) with 20% human albumin may facilitate less fluid and vasopressor administration than FBT with crystalloid...

Calcium supplementation during trauma resuscitation: a propensity score-matched analysis from the TraumaRegister DGU® Dries Helsloot, Mark Fitzgerald, Rolf Lefering, et al Critical Care volume 28, Article number: 222 (2024) Abstract Background In major trauma patients, hypocalcemia is associated with increased mortality. Despite the absence of strong evidence on causality, early calcium supplementation has been recommended. This study investigates whether c...

Original Investigation  Critical Care Medicine July 12, 2024 Barriers, Solutions, and Opportunities for Adapting Critical Care Clinical Trials in the COVID-19 Pandemic Deborah Cook, Shipra Taneja, Karla Krewulak, et al JAMA Netw Open. 2024;7(7):e2420458. doi:10.1001/jamanetworkopen.2024.20458 Key Points Question  What barriers, solutions, and opportunities were associated with continuing crit...