Original Investigation  August 21, 2024 High Fresh Frozen Plasma to Red Blood Cell Ratio and Survival Outcomes in Blunt Trauma Gaku Fujiwara, Yohei Okada, Wataru Ishii, et al JAMA Surg. 2024;159(11):1272-1280. doi:10.1001/jamasurg.2024.3097 Key Points Question  What is the association of a high fresh frozen plasma (FFP) to red blood cell (RBC) ratio with survival outcomes in patients with severe blunt tra...

Distinct Clinical Endpoints of Staphylococcus aureus Bacteraemia Complicate Assessment of Outcome  Clark D Russell,  Karla Berry,  George Cooper,  et al Clinical Infectious Diseases, Volume 79, Issue 3, 15 September 2024, Pages 604–611, https://doi.org/10.1093/cid/ciae281 Abstract Background We aimed to test the hypothesis that development of metastatic infection represents a distinct clinical endpoint from death due to&nb...

Original Investigation  August 28, 2024 Outcomes of Patients With Traumatic Brain Injury Transferred to Trauma Centers Sai Krishna Bhogadi, Collin Stewart, Hamidreza Hosseinpour, et al JAMA Surg. 2024;159(11):1282-1288. doi:10.1001/jamasurg.2024.3254 Key Points Question  What happens to patients with traumatic brain injury (TBI) who are transferred to higher-level trauma centers? Findings  In...

Preventing New Gram-negative Resistance Through Beta-lactam De-escalation in Hospitalized Patients With Sepsis: A Retrospective Cohort Study  Besu F Teshome,  Taehwan Park,  Joel Arackal,  et al Clinical Infectious Diseases, Volume 79, Issue 4, 15 October 2024, Pages 826–833, https://doi.org/10.1093/cid/ciae253 Abstract Background Whether antibiotic de-escalation reduces the risk of subsequent antibiotic resistance is...

Original Investigation  November 11, 2024 Intratracheal Budesonide Mixed With Surfactant for Extremely Preterm Infants: The PLUSS Randomized Clinical Trial Brett J. Manley, C. Omar F. Kamlin, Susan M. Donath, et al JAMA. Published online November 11, 2024. doi:10.1001/jama.2024.17380 Key Points Question  What is the effect of intratracheal budesonide mixed with surfactant on survival free of...

Association Between Infectious Diseases Consultation and Mortality in Hospitalized Patients With Gram-negative Bloodstream Infection: A Retrospective Population-wide Cohort Study  Sean W X Ong,  Jin Luo,  Daniel J Fridman,  et al Clinical Infectious Diseases, Volume 79, Issue 4, 15 October 2024, Pages 855–863, https://doi.org/10.1093/cid/ciae282 Abstract Objectives Data supporting routine infectious diseases (ID) cons...

Original Investigation  September 25, 2024 Fever Prevention in Patients With Acute Vascular Brain Injury: The INTREPID Randomized Clinical Trial David M. Greer, Raimund Helbok, Neeraj Badjatia, et al JAMA. 2024;332(18):1525-1534. doi:10.1001/jama.2024.14745 Key Points Question  Is an automated surface temperature management device effective in prevention of fever in patients with acute vascular brain inju...

Hospital-Acquired and Ventilator-Associated Pneumonia Early After Lung Transplantation: A Prospective Study on Incidence, Pathogen Origin, and Outcome Laura N Walti,  Chun Fai Ng,  Qasim Mohiuddin,  et al Clinical Infectious Diseases, Volume 79, Issue 4, 15 October 2024, Pages 1010–1017, https://doi.org/10.1093/cid/ciae399 Abstract Background Hospital-acquired (HAP) and ventilator-associated pneumonia (VAP) are important c...

Original Investigation  Medical Education November 8, 2024 Perceived Mistreatment and Professional Identity of Medical Students in China Xuanxuan Ma, Ziyue Shen, Ruilian Xiao, et al JAMA Netw Open. 2024;7(11):e2444245. doi:10.1001/jamanetworkopen.2024.44245 Key Points Question  Is perceived mistreatment during medical school associated with medical students’ professional identity? Findings...

ONLINE FIRST (FREE ACCESS) ICU TOOLBOX TOPICAL COLLECTION Editorial How I perform diaphragmatic ultrasound in the intensive care unitHermans G., Demoule A. and Heunks L. Invasive fungal infections in non-neutropenic patientsKreitmann L., Blot S. and Nseir S. My echo checklist in venoarterial ECMO patientsSaura O., Combes A. and Hekimian G. Preventing stress ulcer bleedingYoung P. J., Cook D. J. and Deanede A. M. OPEN ACCESS ~ Editorial Managing blo...