CLINICAL RESEARCH: ACUTE KIDNEY INJURY AND ICU NEPHROLOGY Averaged versus Persistent Reduction in Urine Output to Define Oliguria in Critically Ill Patients An Observational Study Monard, Céline; Bianchi, Nathan; Kelevina, Tatiana; et al Clinical Journal of the American Society of Nephrology 19(9):p 1089-1097, September 2024 Abstract Key Points  When assessing urine output, consideration of an average or persistent value below a thresh...

Original Investigation  Pediatrics October 29, 2024 Outpatient Antibiotic Use and Treatment Failure Among Children With Pneumonia Daniel J. Shapiro, Matt Hall, Mark I. Neuman, et al JAMA Netw Open. 2024;7(10):e2441821. doi:10.1001/jamanetworkopen.2024.41821 Key Points Question  In children with pneumonia managed as outpatients, is receipt of antibiotics associated with decreased risk of treat...

Original Investigation  Pediatrics October 29, 2024 Sociodemographic Disparities in 1-Year Outcomes of Children With Community-Acquired Acute Kidney Injury Omer S. Ashruf, Zaid Ashruf, Valerie Luyckx, et al JAMA Netw Open. 2024;7(10):e2440988. doi:10.1001/jamanetworkopen.2024.40988 Key Points Question  Do disparities in clinical outcomes persist along sociodemographic lines among children with communit...

ORIGINAL ARTICLE A Comparison of Peripherally Inserted Central Catheter Materials Amanda J. Ullman, Deanne August, Tricia M. Kleidon, et al N Engl J Med 2025;392:161-172 Abstract BACKGROUND New catheter materials for peripherally inserted central catheters (PICCs) may reduce the risk of device failure due to infectious, thrombotic, and catheter occlusion events. However, data from randomized trials comparing these catheters are lacking. METHODS We ...

Original Investigation  Pediatrics October 30, 2024 Maternal-Newborn ABO Blood Groups and Risk of Bacterial Infection in Newborns Emily Ana Butler, Joel G. Ray, Eyal Cohen JAMA Netw Open. 2024;7(10):e2442227. doi:10.1001/jamanetworkopen.2024.42227 Key Points Question  If a mother and newborn have incongruent ABO blood groups, is the newborn at a lower risk of bacterial infection than if they had c...

Research Letter  Pediatrics October 31, 2024 Caregiver Awareness and Knowledge of Acute Kidney Injury in Hospitalized Children Michelle C. Starr, Julia Vanderkolk, Shrea Goswami, et al JAMA Netw Open. 2024;7(10):e2442442. doi:10.1001/jamanetworkopen.2024.42442 Introduction Acute kidney injury (AKI) occurs commonly in pediatrics and is associated with poor outcomes.1 Adult patients with AKI are oft...

Original Investigation  Anesthesiology November 1, 2024 Pulmonary Atelectasis After Sedation With Propofol vs Propofol-Ketamine for Magnetic Resonance Imaging in Children: A Randomized Clinical Trial Yu Jeong Bang, Jeayoun Kim, Nam-Su Gil, et al JAMA Netw Open. 2024;7(11):e2433029. doi:10.1001/jamanetworkopen.2024.33029 Key Points Question  What is the incidence of atelectasis among children ...

Intraosseous or Intravenous Vascular Access for Out-of-Hospital Cardiac Arrest Mikael F. Vallentin, Asger Granfeldt, Thomas L. Klitgaard, et al N Engl J Med Published October 31, 2024 DOI: 10.1056/NEJMoa2407616 Abstract BACKGROUND Out-of-hospital cardiac arrest is a leading cause of death worldwide. Establishing vascular access is critical for administering guideline-recommended drugs during cardiopulmonary resuscitation. Both the intraosseous route and ...

ORIGINAL ARTICLE A Randomized Trial of Drug Route in Out-of-Hospital Cardiac Arrest Keith Couper, Chen Ji, Charles D. Deakin, et al N Engl J Med Published October 31, 2024 DOI: 10.1056/NEJMoa2407780 Abstract BACKGROUND Out-of-hospital cardiac arrest is a leading cause of death worldwide. Establishing vascular access is critical for administering guideline-recommended drugs during cardiopulmonary resuscitation. Both the intraosseous route and the intra...

Research Association of holidays and the day of the week with suicide risk: multicountry, two stage, time series study Whanhee Lee, Cinoo Kang, Chaerin Park, et al BMJ 2024; 387 doi: https://doi.org/10.1136/bmj-2024-077262 (Published 23 October 2024)Cite this as: BMJ 2024;387:e077262 Abstract Objectives To assess the short term temporal variations in suicide risk related to the day of the week and national holidays in multiple countries. Design ...