CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 163, ISSUE 6, P1425-1436, JUNE 2023Download Full Issue New and Persistent Sedative Prescriptions Among Older Adults Following a Critical Illness: A Population-Based Cohort Study Lisa D. Burry, Chaim M. Bell, Andrea Hill, et al Chest 2023; 163: 1425-1436 Published:January 04, 2023 DOI:https://doi.org/10.1016/j.chest.2022.12.033 Background ICU survivors often have complex care needs and can experience...

CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 163, ISSUE 6, P1437-1447, JUNE 2023Download Full Issue Is Left Ventricular Systolic Dysfunction Associated With Increased Mortality Among Patients With Sepsis and Septic Shock? Siddharth Dugar, Ryota Sato, Sanchit Chawla, et al Chest 2023; 163: 1437-1447 Published:January 13, 2023 DOI:https://doi.org/10.1016/j.chest.2023.01.010 Background The impact of left ventricular (LV) systolic function on outc...

CHEST INFECTIONS: ORIGINAL RESEARCH| VOLUME 163, ISSUE 6, P1380-1389, JUNE 2023Download Full Issue Guideline-Concordant Antibiotic Therapy for the Hospital Treatment of Community-Acquired Pneumonia and 1-Year All-Cause and Cardiovascular Mortality in Older Adult Patients Surviving to Discharge Vicente F. Corrales-Medina, Carl van Walraven Chest 2023; 163: 1380-1389 Published:January 04, 2023 DOI:https://doi.org/10.1016/j.chest.2022.12.035 Bac...

CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 164, ISSUE 1, P101-113, JULY 2023Download Full Issue Monocyte Distribution Width as a Diagnostic Marker for Infection: A Systematic Review and Meta-analysis Alexandra Malinovska, Benjamin Hernried, Andrew Lin, et al Chest 2023; 164: 101-113 Published:January 18, 2023 DOI:https://doi.org/10.1016/j.chest.2022.12.049 Background Monocyte distribution width (MDW) is an emerging biomarker for infection. I...

CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 164, ISSUE 1, P90-100, JULY 2023Download Full Issue Contamination of Blood Cultures From Arterial Catheters and Peripheral Venipuncture in Critically Ill Patients: A Prospective Multicenter Diagnostic Study Izumi Nakayama, Junichi Izawa, Koichiro Gibo, et al Chest 2023; 164: 90-100 Published:January 29, 2023 DOI:https://doi.org/10.1016/j.chest.2023.01.030 Background Collecting blood cultures from in...

RESEARCH ARTICLE Patterns of antibiotic use, pathogens, and prediction of mortality in hospitalized neonates and young infants with sepsis: A global neonatal sepsis observational cohort study (NeoOBS) Neal J. Russell, Wolfgang Stöhr, Nishad Plakkal, et al PLoS Med Published: June 8, 2023 https://doi.org/10.1371/journal.pmed.1004179 Abstract Background There is limited data on antibiotic treatment in hospitalized neonates in low- and middle-income coun...

Original Investigation  July 10, 2023 Abatacept, Cenicriviroc, or Infliximab for Treatment of Adults Hospitalized With COVID-19 Pneumonia: A Randomized Clinical Trial Jane A. O’Halloran, Emily R. Ko, Kevin J. Anstrom, et al JAMA. Published online July 10, 2023. doi:10.1001/jama.2023.11043 Key Points Question  Do abatacept, cenicriviroc, or infliximab improve time to recovery for patients hospitalized with COVID-19 pneumonia compa...

ARTICLES|ONLINE FIRST Intravenous aviptadil and remdesivir for treatment of COVID-19-associated hypoxaemic respiratory failure in the USA (TESICO): a randomised, placebo-controlled trial Samuel M Brown, Christina E Barkauskas, Birgit Grund, et al Lancet Respir Med Published:June 19, 2023DOI:https://doi.org/10.1016/S2213-2600(23)00147-9 Summary Background There is a clinical need for therapeutics for COVID-19 patients with acute hypoxemic respiratory fail...

Original Open Access Published: 13 May 2023 Acute traumatic coma awakening by right median nerve electrical stimulation: a randomised controlled trial Xiang Wu, Li Xie, Jin Lei, et al Intensive Care Medicine volume 49, pages 633–644 (2023) Abstract Purpose Severe traumatic brain injury (TBI) leads to acute coma and may result in prolonged disorder of consciousness (pDOC). We aimed to determine whether right median nerve e...

ONLINE FIRST (FREE ACCESS) LATEST ARTICLES OriginalsGiving a voice to patients at high risk of dying in the intensive care unit: a multiple source approachGrasselli G. et al. OPEN ACCESS ~ OriginalSepsis-associated acute kidney injury in the intensive care unit: incidence, patient characteristics, timing, trajectory, treatment, and associated outcomes. A multicenter, observational studyWhite K.C. et al. OPEN ACCESSMachine learning to predict poor school perfor...