[Chest发表论文]:头孢曲松预防院外心跳骤停昏迷患者的早发性肺炎已关闭评论
CRITICAL CARE: ORIGINAL RESEARCH
Ceftriaxone to Prevent Early-Onset Pneumonia in Comatose Patients Following Out-of-Hospital Cardiac Arrest: A Pilot Randomized Controlled Trial and Resistome Assessment (PROTECT)
David J. Gagnon, Kristin M. Burkholder, Bram J. Geller, et al
Chest 2025; 169: 115-127
DOI: 10.1016/j.chest.2025.08.007
Abstract
Background
Antibiotic prophylaxis following out-of-hospital cardiac arrest (OHCA) reduces early-onset pneumonia. ...
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[JAMA Intern Med发表论文]:新冠疫情后美国长期护理机构容量的改变已关闭评论
Original Investigation
Aging and Health
Changes in US Skilled Nursing Facility Capacity Following the COVID-19 Pandemic
Brian E. McGarry, Andrew D. Wilcock, Ashvin D. Gandhi, et al
JAMA Intern Med Published Online: January 12, 2026
doi: 10.1001/jamainternmed.2025.7197
Key Points
Question Has US skilled nursing facility (SNF) capacity changed following the COVID-19 pandemic?
Findings ...
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[JAMA Pediatr发表论文]:美国儿科住院床位的变化趋势已关闭评论
Research Letter
National Trends in Pediatric Inpatient Capacity
Kenneth A. Michelson, Anna M. Cushing, Emily M. Bucholz
JAMA Pediatr 2025;179;(2):208-209. doi:10.1001/jamapediatrics.2024.5110
Most pediatric hospitalizations occur in general hospitals, which increasingly transfer rather than hospitalize children, resulting in care concentration at large pediatric centers.1 This shift in pediatric care delivery is partly ...
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[Crit Care Med发表论文]:感染性休克的目标性组织灌注治疗与大循环指导的标准治疗已关闭评论
CLINICAL INVESTIGATION
Targeted Tissue Perfusion Versus Macrocirculatory-Guided Standard Care in Patients With Septic Shock: A Randomized Clinical Trial—The TARTARE-2S Trial
Pettilä, Ville; Pfortmüller, Carmen A; Perner, Anders; et al
Critical Care Medicine 54(1):p 24-34, January 2026. | DOI: 10.1097/CCM.0000000000006899
Abstract
Objectives:
To determine whether treatment targeting improving tissue perfusion while allowing lower than recommende...
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[JAMA Intern Med发表论文]:私家安装AED的效果及成本效益分析已关闭评论
Original Investigation
Effectiveness and Cost-Effectiveness of Automated External Defibrillators in Private Homes: A Report From the Cardiac Arrest Registry to Enhance Survival
Lars W. Andersen, Mathias J. Holmberg, Eline Krijkamp, et al
JAMA Intern Med 2026;186;(1):37-43. doi:10.1001/jamainternmed.2025.6123
Key Points
Question Are automated external defibrillations (AEDs) in private homes effective and co...
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Intensive Care Medicine在线免费阅读已关闭评论
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MY GREEN ICU
Correspondence
Integrating sustainability into critical care undergraduate education: preparing future physicians for a climate-conscious practice. Author's replyBoissier, F., Poissy, J., Lecronier, M. et al.
STANDARD OF CARE IN THE INTENSIVE CARE UNIT
Editorial
Stepwise fluid management in critical illnessMekontso Dessap, A., Cecconi, M.
LATEST ARTICLES
EditorialChecking methodology and statistics when readi...
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[JAMA Netw Open发表论文]:急诊科气管插管时的氯胺酮、依托咪酯与病死率已关闭评论
Original Investigation
Emergency Medicine
Ketamine, Etomidate, and Mortality in Emergency Department Intubations
Ian Ward A. Maia, Sérgio R. R. Decker, Lucas Oliveira J. e Silva, et al
JAMA Netw Open 2025;8;(12):e2548060. doi:10.1001/jamanetworkopen.2025.48060
Key Points
Question Among critically ill adults undergoing rapid sequence intubation, is etomidate use associated with higher in-hospital mortali...
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[JAMA Netw Open发表论文]:机械通气患者使用泮托拉唑预防上消化道出血的成本效益分析已关闭评论
Original Investigation
Critical Care Medicine
Cost-Effectiveness of Pantoprazole to Prevent Upper Gastrointestinal Bleeding in Mechanically Ventilated Patients
Feng Xie, Yifan Yao, Yue Ma, et al
JAMA Netw Open 2025;8;(12):e2552771. doi:10.1001/jamanetworkopen.2025.52771
Key Points
Question Is daily intravenous pantoprazole cost-effective in preventing upper gastrointestinal bleeding in mechanically vent...
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Intensive Care Medicine免费在线阅读已关闭评论
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STANDARD OF CARE IN THE INTENSIVE CARE UNIT
What's New in Intensive Care
Ten ethical challenges in donation after circulatory death (DCD): a practical guide for intensivistsVergano, M., Metaxa, V. & Citerio, G.
LATEST ARTICLES
OriginalTrends in renal replacement therapy use in intensive care unit: insights from a French multicenter cohortSchmidt, J., Grimaldi, L., Martel, P. et al.
OPEN ACCESS ~ Original
Temporal ro...
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[JAMA Intern Med发表论文]:社区起病成年脓毒症患者的抗生素降阶梯治疗已关闭评论
Original Investigation
Less Is More
Antibiotic De-Escalation in Adults Hospitalized for Community-Onset Sepsis
Ashwin B. Gupta, Megan Heath, Emily Walzl, et al
JAMA Intern Med Published Online: December 22, 2025
doi: 10.1001/jamainternmed.2025.6919
Key Points
Question Is broad-spectrum antibiotic de-escalation on encounter day 4 safe among patients hospitalized with community-onset sepsis w...
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