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ARTICLES| VOLUME 9, ISSUE 8, P851-862, AUGUST 01, 2021 Extracorporeal membrane oxygenation network organisation and clinical outcomes during the COVID-19 pandemic in Greater Paris, France: a multicentre cohort study Guillaume Lebreton, Matthieu Schmidt, Maharajah Ponnaiah, et al Lancet Respir Med 2021; 9: 851-862 DOI:https://doi.org/10.1016/S2213-2600(21)00096-5 Summary Background In the Île-de-France region (henceforth termed Greater P...
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ORIGINAL ARTICLE Immediate versus Postponed Intervention for Infected Necrotizing Pancreatitis Lotte Boxhoorn, Sven M. van Dijk, Janneke van Grinsven, et al N Engl J Med 2021; 385:1372-1381DOI: 10.1056/NEJMoa2100826 Abstract BACKGROUND Infected necrotizing pancreatitis is a potentially lethal disease that is treated with the use of a step-up approach, with catheter drainage often delayed until the infected necrosis is encapsulated. Whether outcomes could...
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ARTICLES|ONLINE FIRST Cyclophosphamide added to glucocorticoids in acute exacerbation of idiopathic pulmonary fibrosis (EXAFIP): a randomised, double-blind, placebo-controlled, phase 3 trial Jean-Marc Naccache, Stéphane Jouneau, Morgane Didier, et al Lancet Respir Med Published:September 07, 2021 DOI:https://doi.org/10.1016/S2213-2600(21)00354-4 Summary Background The use of cyclophosphamide in patients with acute exacerbation of idiopathic pulmonary ...
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ARTICLES|ONLINE FIRST Awake prone positioning for COVID-19 acute hypoxaemic respiratory failure: a randomised, controlled, multinational, open-label meta-trial Stephan Ehrmann, Jie Li, Miguel Ibarra-Estrada, et al Lancet Respir Med Published:August 20, 2021 DOI:https://doi.org/10.1016/S2213-2600(21)00356-8 Summary Background Awake prone positioning has been reported to improve oxygenation for patients with COVID-19 in retrospective and observational s...
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ARTICLES | ONLINE FIRST Inhaled isoflurane via the anaesthetic conserving device versus propofol for sedation of invasively ventilated patients in intensive care units in Germany and Slovenia: an open-label, phase 3, randomised controlled, non-inferiority trial Andreas Meiser, Thomas Volk, Jan Wallenborn, et al Lancet Respir Med Published:August 26, 2021 DOI:https://doi.org/10.1016/S2213-2600(21)00323-4 Summary Background Previous studies indicate tha...
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ARTICLES|ONLINE FIRST Daily testing for contacts of individuals with SARS-CoV-2 infection and attendance and SARS-CoV-2 transmission in English secondary schools and colleges: an open-label, cluster-randomised trial Bernadette C Young, David W Eyre, Saroj Kendrick, et al Lancet Published:September 14, 2021 DOI:https://doi.org/10.1016/S0140-6736(21)01908-5 Summary Background School-based COVID-19 contacts in England have been asked to self-isolate at home...
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Original Investigation September 21, 2021 Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial Jennie Johnstone, Maureen Meade, François Lauzier, et al JAMA. 2021;326(11):1024-1033. doi:10.1001/jama.2021.13355 Abstract Importance  Growing interest in microbial dysbiosis during critical illness has raised questions about the therapeutic potential of microbiome modifi...
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ONLINE FIRST (FREE ACCESS) OriginalsManagement of arterial partial pressure of carbon dioxide in the first week after traumatic brain injury: results from the CENTER-TBI studyCiterio G. et al.Occurrence and timing of withdrawal of life-sustaining measures in traumatic brain injury patients: a CENTER-TBI studyvan Veen E. et al. Correspondances“L’histoire se répète”, one size does not fit allKuindersma M. and Spronk P.E.“L'histoire se répète”, one size does not fi...
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ORIGINAL ARTICLE Protection of BNT162b2 Vaccine Booster against Covid-19 in Israel Yinon M. Bar-On, Yair Goldberg, Micha Mandel, et al N Engl J Med September 15, 2021DOI: 10.1056/NEJMoa2114255 Abstract BACKGROUND On July 30, 2021, the administration of a third (booster) dose of the BNT162b2 messenger RNA vaccine (Pfizer–BioNTech) was approved in Israel for persons who were 60 years of age or older and who had received a second dose of vaccine at lea...
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ARTICLES| VOLUME 398, ISSUE 10302, P747-758, AUGUST 28, 2021 1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study Lixue Huang, Qun Yao, Xiaoying Gu, et al Lancet 2021; 398: 747-758 Summary Background The full range of long-term health consequences of COVID-19 in patients who are discharged from hospital is largely unclear. The aim of our study was to comprehensively compare consequences between 6 months and 12 m...
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