Original Investigation  April 10, 2025 Olfactory Deficits and Mortality in Older Adults Robert Ruane, Oliver Lampert, Maria Larsson, et al JAMA Otolaryngol Head Neck Surg. Published online April 10, 2025. doi:10.1001/jamaoto.2025.0174 Key Points Question  Is there an association between olfactory deficits and mortality in older adults, and what are the key mediating factors and cause-specific ou...

Original Investigation  May 12, 2025 Antihypertensive Medication Timing and Cardiovascular Events and Death: The BedMed Randomized Clinical Trial Scott R. Garrison, Jeffrey A. Bakal, Michael R. Kolber, et al JAMA. Published online May 12, 2025. doi:10.1001/jama.2025.4390 Key Points Question  Does bedtime administration of blood pressure–lowering medication, compared with conventional morning use...

Original Investigation  Health Policy May 2, 2025 State-Level Tax Policy, Cancer Screening, and Mortality Rates in the US Odysseas P. Chatzipanagiotou, Mujtaba Khalil, Usama Waqar, et al JAMA Netw Open. 2025;8(5):e258455. doi:10.1001/jamanetworkopen.2025.8455 Key Points Question  Are state-level tax revenue and tax progressivity associated with cancer screening and cancer mortality rates in t...

Article Published: 28 April 2025 Artificial intelligence based multispecialty mortality prediction models for septic shock in a multicenter retrospective study Shurui Wang, Xinyi Liu, Shaohua Yuan, et al npj Digital Medicine volume 8, Article number: 228 (2025) Abstract Septic shock is one of the most lethal conditions in ICU, and early risk prediction may help reduce mortality. We developed a TOPSIS-based Classification Fusion (TCF) model to pred...

Original Investigation  Anesthesiology May 2, 2025 Hospital and Clinician Practice Variation in Cardiac Surgery and Postoperative Acute Kidney Injury Michael R. Mathis, Graciela B. Mentz, Jie Cao, et al JAMA Netw Open. 2025;8(5):e258342. doi:10.1001/jamanetworkopen.2025.8342 Key Points Question  Are specific hospital- and clinician-level operating room practices important factors in interhosp...

Original Investigation  March 6, 2025 Butter and Plant-Based Oils Intake and Mortality Yu Zhang, Katia S. Chadaideh, Yanping Li, et al JAMA Intern Med. 2025;185(5):549-560. doi:10.1001/jamainternmed.2025.0205 Key Points Question  What are the associations of long-term intakes of butter and plant-based oils with mortality in the US population? Findings  In this cohort study of 221 054 adults f...

Original Investigation  March 17, 2025 Nudging Clinicians to Promote Serious Illness Communication for Critically Ill Patients: A Pragmatic Cluster Randomized Trial  Katherine R. Courtright, Jaspal Singh, Erich M. Dress, et al JAMA Intern Med. 2025;185(5):510-520. doi:10.1001/jamainternmed.2025.0090 Key Points Question  Does nudging intensive care unit (ICU) clinicians to adhere to communication guid...

Original Investigation  May 5, 2025 Physician- and Large Language Model–Generated Hospital Discharge Summaries Christopher Y. K. Williams, Charumathi Raghu Subramanian, Syed Salman Ali, et al JAMA Intern Med. Published online May 5, 2025. doi:10.1001/jamainternmed.2025.0821 Key Points Question  Can large language models (LLMs) draft hospital discharge summary narratives of comparable quality and...

Original Investigation  Emergency Medicine May 2, 2025 Emergency Department Triage Accuracy and Delays in Care for High-Risk Conditions Dana R. Sax, E. Margaret Warton, Dustin G. Mark, et al JAMA Netw Open. 2025;8(5):e258498. doi:10.1001/jamanetworkopen.2025.8498 Key Points Question  Is there an association between emergency department (ED) triage accuracy and timeliness of care among patient...

Article Higher mortality in female versus male critically ill patients at comparable thresholds of mechanical power: necessity of normalization to functional lung size Dario von Wedel, Simone Redaelli, Boris Jung, et al Intensive Care Med 2025; 51: 624-626 Published: 23 January 2025 Dear Editor, Mechanical power (MP) is an integrative target to minimize risk of ventilator-induced lung injury (VILI) [1]. Estimating the energy delivered by the ventilator t...