Molnupiravir or nirmatrelvir–ritonavir plus usual care versus usual care alone in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial RECOVERY Collaborative Group Lancet Infect Dis Available online 15 May 2025 https://doi.org/10.1016/S1473-3099(25)00093-3 Summary Background Molnupiravir and nirmatrelvir–ritonavir are oral antivirals that have shown efficacy in preventing disease progression in outp...

Original Investigation  Geriatrics May 30, 2025 Parental Education, Own Education, and Cognitive Function in Middle-Aged and Older Adults Shengyu Luo, Weiqing Chen, Wanting Hu, et al JAMA Netw Open. 2025;8(5):e2513036. doi:10.1001/jamanetworkopen.2025.13036 Key Points Question  Are maternal and paternal education associated with cognitive declines in middle-aged and older adults, and do individuals’ own education mediate these...

Original Investigation  May 28, 2025 Hospital Ownership and Surgical Outcomes in East, Central, and Southern Africa Robert K. Parker, Yves Yankunze, Andrea S. Parker, et al JAMA Surg. Published online May 28, 2025. doi:10.1001/jamasurg.2025.1430 Key Points Question  Is hospital ownership type associated with surgical mortality rates in East, Central, and Southern Africa? Findings  I...

Original Investigation  May 28, 2025 Familiarity of the Surgeon-Anesthesiologist Dyad and Major Morbidity After High-Risk Elective Surgery Julie Hallet, Angela Jerath, Pablo Perez d’Empaire, et al JAMA Surg. Published online May 28, 2025. doi:10.1001/jamasurg.2025.1386 Key Points Question  Is familiarity of the surgeon-anesthesiologist dyad associated with 90-day major morbidity after high-risk ...

Research Letter  Equity, Diversity, and Inclusion May 28, 2025 Medical School Ranking and Neighborhood Characteristics of Initial Practice Location Among Physicians Navapat Nananukul, Mayank Kejriwal JAMA Netw Open. 2025;8(5):e2512474. doi:10.1001/jamanetworkopen.2025.12474 Introduction The US has experienced a chronic shortage of physicians in certain geographic regions, especially those that may be deprived.1 ...

Original Investigation  Emergency Medicine May 20, 2025 Preoxygenation With and Without Positive End-Expiratory Pressure in Lung-Healthy Volunteers: A Randomized Clinical Trial Giulia Roveri, Anna Camporesi, Alex Hofer, et al JAMA Netw Open. 2025;8(5):e2511569. doi:10.1001/jamanetworkopen.2025.11569 Key Points Question  Is there a difference in the efficacy of 3 preoxygenation devices for use...

Original Investigation  Nephrology May 27, 2025 Hydrocortisone and Risk Factors for Kidney Replacement Therapy in Septic Shock Lachlan H. Donaldson, Anthony Devaux, Kyle C. White, et al JAMA Netw Open. 2025;8(5):e2512279. doi:10.1001/jamanetworkopen.2025.12279 Key Points Question  In patients with septic shock, is the administration of intravenous hydrocortisone independently associated with subsequent rates of kidney replacem...

Original Investigation  May 21, 2025 Hemodynamic Impact of Cipepofol vs Propofol During Anesthesia Induction in Patients With Severe Aortic Stenosis: A Randomized Clinical Trial Tingting Ni, Xiaoxia Zhou, Shuguang Wu, et al JAMA Surg. Published online May 21, 2025. doi:10.1001/jamasurg.2025.1299 Key Points Question  Does cipepofol offer superior hemodynamic stability compared to propofol as an anesthesia induction agent? Findings&nb...

Original Investigation  Pediatrics March 25, 2025 Risk Factors for Health Care–Associated Bloodstream Infections in NICUs Julia Johnson, Sudhir Malwade, Sharad Agarkhedkar, et al JAMA Netw Open. 2025;8(3):e251821. doi:10.1001/jamanetworkopen.2025.1821 Key Points Question  What risk factors are associated with neonatal health care–associated bloodstream infections (BSIs) in low-resource settin...

Research Effects of a general practitioner-led brief narrative exposure intervention on symptoms of post-traumatic stress disorder after intensive care (PICTURE): multicentre, observer blind, randomised controlled trial Jochen Gensichen, Konrad F R Schmidt, Linda Sanftenberg, et al BMJ 2025; 389 doi: https://doi.org/10.1136/bmj-2024-082092 (Published 07 May 2025)Cite this as: BMJ 2025;389:e082092 Abstract Objective To d...