ARTICLES|ONLINE FIRST Ultra-low tidal volume ventilation for COVID-19-related ARDS in France (VT4COVID): a multicentre, open-label, parallel-group, randomised trial Jean-Christophe Richard, Nicolas Terzi, Hodane Yonis, et al Lancet Respir Med Published:July 12, 2023DOI:https://doi.org/10.1016/S2213-2600(23)00221-7 Summary Background COVID-19-related acute respiratory distress syndrome (ARDS) is associated with a high mortality rate and longer mechanical ...

Original Investigation  Less Is More July 3, 2023 Hospital Culture and Intensity of End-of-Life Care at 3 Academic Medical Centers Elizabeth Dzeng, Jason N. Batten, Daniel Dohan, et al JAMA Intern Med. Published online July 3, 2023. doi:10.1001/jamainternmed.2023.2450 Key Points Question  What is the role of hospital culture and institutional structures in the provision of potentially nonbeneficial, high-intensity life-sustain...

Original Investigation  July 25, 2023 Identifying Children Likely to Benefit From Antibiotics for Acute Sinusitis: A Randomized Clinical Trial Nader Shaikh, Alejandro Hoberman, Timothy R. Shope, et al JAMA. 2023;330(4):349-358. doi:10.1001/jama.2023.10854 Key Points Question  In children aged 2 to 11 years with acute sinusitis, does the efficacy of antibiotic treatment differ based on nasopharyn...

Research Associations between self-reported healthcare disruption due to covid-19 and avoidable hospital admission: evidence from seven linked longitudinal studies for England Mark A Green, Martin McKee, Olivia KL Hamilton, et al BMJ 2023; 382 doi: https://doi.org/10.1136/bmj-2023-075133 (Published 19 July 2023)Cite this as: BMJ 2023;382:e075133 Abstract Objectives To examine whether there is an association between people who experienced disrupted acce...

Research Evaluating trends in private equity ownership and impacts on health outcomes, costs, and quality: systematic review Alexander Borsa, Geronimo Bejarano, Moriah Ellen, et al BMJ 2023; 382 doi: https://doi.org/10.1136/bmj-2023-075244 (Published 19 July 2023)Cite this as: BMJ 2023;382:e075244 Abstract Objective To review the evidence on trends and impacts of private equity (PE) ownership of healthcare operators. Design Systematic review. ...

Research Educational inequalities in mortality and their mediators among generations across four decades: nationwide, population based, prospective cohort study based on the ChinaHEART project Jiapeng Lu, Chaoqun Wu, Xiaoyan Zhang, et al BMJ 2023; 382 doi: https://doi.org/10.1136/bmj-2022-073749 (Published 19 July 2023)Cite this as: BMJ 2023;382:e073749 Abstract Objectives To assess the different educational inequalities in mortality among generations ...

Original Investigation  July 18, 2023 Accelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease Shaan Khurshid, Mostafa A. Al-Alusi, Timothy W. Churchill, et al JAMA. 2023;330(3):247-252. doi:10.1001/jama.2023.10875 Key Points Question  Does engagement in moderate to vigorous physical activity, with most activity concentrated within 1 to 2 days of the week (ie, a “weekend warrior” pattern), con...

CHEST INFECTIONS: ORIGINAL RESEARCH| VOLUME 163, ISSUE 1, P77-88, JANUARY 2023Download Full Issue Machine-Learning Model for Mortality Prediction in Patients With Community-Acquired Pneumonia: Development and Validation Study Catia Cilloniz, Logan Ward, Mads Lause Mogensen, et al Chest 2023; 163: 77-88 Published:July 15, 2022 DOI:https://doi.org/10.1016/j.chest.2022.07.005 Background Artificial intelligence tools and techniques such as machine learning (...

Research Prevalence and predictors of data and code sharing in the medical and health sciences: systematic review with meta-analysis of individual participant data Daniel G Hamilton, Kyungwan Hong, Hannah Fraser, et al BMJ 2023; 382 doi: https://doi.org/10.1136/bmj-2023-075767 (Published 11 July 2023)Cite this as: BMJ 2023;382:e075767 Abstract Objectives To synthesise research investigating data and code sharing in medicine and health to establish an a...

ASTHMA: ORIGINAL RESEARCH| VOLUME 163, ISSUE 1, P38-51, JANUARY 2023 Extracorporeal Membrane Oxygenation for Refractory Asthma Exacerbations With Respiratory Failure Jonathan K. Zakrajsek, Sung-Joon Min, P. Michael Ho, et al Chest 2023; 163: 38-51 Published:September 29, 2022 DOI:https://doi.org/10.1016/j.chest.2022.09.029 Background Asthma exacerbations with respiratory failure (AERF) are associated with hospital mortality of 7% to 15%. Extracorpor...