#LIVES2019: Findings from the NONSEDA Study Palle Toft of Odense University Hospital presented the findings of the “No sedation compared to sedation with a daily wake-up trial. A prospective randomized multicentre study - The NONSEDA-study” @ESICM in Berlin. The NON-SEDA study is a Scandinavian multicentre study conducted in Denmark, Norway, and Sweden that compared non-sedation with light sedation or arousable sedation. Only 8 intensive care units were included, b...

ARTICLES|ONLINE FIRST Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation Conor L Mallucci, Michael D Jenkinson, Elizabeth J Conroy, et al Lancet Published:September 12, 2019 DOI:https://doi.org/10.1016/S0140-6736(19)31603-4 Summary Background 背景 Insertion of a ventriculoperitoneal shunt for hydrocephalus is one of the commonest neurosurgical procedures world...

#LIVES2019: Highlights from the Opening Ceremony @ESICM The 32nd Annual Congress of ESICM officially opened today at the CityCube in Berlin. At the #LIVES2019 opening ceremony, Jozef Kesecioglu, ESICM President, welcomed all participants. Prof. Kesecioglu offered his thanks to the ESICM team, office members and the executive committee members for their efforts during the last twelve months. He then talked about the creation of a new section in the society – The ...

Research Letter September 3, 2019 Incidence of Maternal Sepsis and Sepsis-Related Maternal Deaths in the United States Matthew K. Hensley, Melissa E. Bauer, Lindsay K. Admon, et al. JAMA. 2019;322(9):890-892. doi:10.1001/jama.2019.9818 Results From 63 665 593 hospitalizations in the NRD (2013-2016), there were 5 957 678 delivery hospitalizations with discharges in January through October, of which 32.5% were...

Original Investigation September 3, 2019 Effect of Low-Intensity vs Standard-Intensity Warfarin Prophylaxis on Venous Thromboembolism or Death Among Patients Undergoing Hip or Knee Arthroplasty: A Randomized Clinical Trial Brian F. Gage, Anne R. Bass, Hannah Lin, et al JAMA. 2019;322(9):834-842. doi:10.1001/jama.2019.12085 Abstract Importance 背景 The optimal international normalized ratio (INR) to preven...

ARTICLES|ONLINE FIRST Personalised mechanical ventilation tailored to lung morphology versus low positive end-expiratory pressure for patients with acute respiratory distress syndrome in France (the LIVE study): a multicentre, single-blind, randomised controlled trial Jean-Michel Constantin, Matthieu Jabaudon, Jean-Yves Lefrant, et al Lancet Respir Med Published:August 06, 2019 DOI:https://doi.org/10.1016/S2213-2600(19)30138-9 Summary Background The effe...

ARTICLES|ONLINE FIRST Contact precautions in single-bed or multiple-bed rooms for patients with extended-spectrum β-lactamase-producing Enterobacteriaceae in Dutch hospitals: a cluster-randomised, crossover, non-inferiority study Marjolein F Q Kluytmans-van den Bergh, Patricia C J Bruijning-Verhagen, Prof Christina M J E Vandenbroucke-Grauls, et al. Lancet Infect Dis Published:August 23, 2019 DOI:https://doi.org/10.1016/S1473-3099(19)30262-2 Summary Backgro...

Original Investigation September 3, 2019 N95 Respirators vs Medical Masks for Preventing Influenza Among Health Care Personnel: A Randomized Clinical Trial Lewis J. Radonovich Jr, Michael S. Simberkoff, Mary T. Bessesen, et al JAMA. 2019;322(9):824-833. doi:10.1001/jama.2019.11645 Abstract Importance 背景 Clinical studies have been inconclusive about the effectiveness of N95 respirators and medical m...

ARTICLES| VOLUME 7, ISSUE 8, P699-709, AUGUST 01, 2019 Eosinophil-guided corticosteroid therapy in patients admitted to hospital with COPD exacerbation (CORTICO-COP): a multicentre, randomised, controlled, open-label, non-inferiority trial Pradeesh Sivapalan, Therese S Lapperre, Julie Janner, et al. Lancet Respir Med 2019; 7: 699-709 DOI:https://doi.org/10.1016/S2213-2600(19)30176-6 Summary Background 背景 Treatment with systemic corticost...

ORIGINAL ARTICLE Ambient Particulate Air Pollution and Daily Mortality in 652 Cities Cong Liu, Renjie Chen, Francesco Sera, et al Abstract BACKGROUND 背景 The systematic evaluation of the results of time-series studies of air pollution is challenged by differences in model specification and publication bias. 由于模型特征的差异以及发表偏倚，系统评估大气污染的时间序列研究受到挑战。 METHODS 方法学 We evaluated the associations of inhalable particulate...