ARTICLES| VOLUME 396, ISSUE 10245, P177-185, JULY 18, 2020 Dexmedetomidine for reduction of atrial fibrillation and delirium after cardiac surgery (DECADE): a randomised placebo-controlled trial Alparslan Turan, Andra Duncan, Steve Leung, et al Lancet Published:July 18, 2020 DOI:https://doi.org/10.1016/S0140-6736(20)30631-0 Summary Background Atrial fibrillation and delirium are common consequences of cardiac surgery. Dexmedetomidine has unique propertie...

ARTICLES| VOLUME 396, ISSUE 10245, P167-176, JULY 18, 2020 Urgent endoscopic retrograde cholangiopancreatography with sphincterotomy versus conservative treatment in predicted severe acute gallstone pancreatitis (APEC): a multicentre randomised controlled trial Nicolien J Schepers, Nora D L Hallensleben, Marc G Besselink, et al Lancet Published:July 18, 2020 DOI:https://doi.org/10.1016/S0140-6736(20)30539-0 Summary Background It remains un...

ICU Management & Practice, Volume 20 - Issue 1, 2020 Intensive Care in the Coronavirus Era: Keep in Mind Your Collective Intelligence Above and beyond the logistical and organisational aspects, shaken by the COVID-19 pandemic, here is an overview of our experience as an intensive care team in Switzerland. We will not parade the efficient measures implemented in our institution in preparation for welcoming COVID-19 patients; rather, we will discuss the im...

ICU Management & Practice, Volume 20 - Issue 1, 2020 A COVID-19 Dashboard: Data Analytics to Aid Resource Allocation in Intensive Care Units In this article, we focus on clinical and practical application of current available cloud-based data analysis to track and benchmark in real-time suspect and confirmed COVID-19 cases, resource use and availability. Introduction The COVID-19 pandemic represents an unprecedented challenge to intensive care units (...

Original Investigation July 28, 2020 Effect of Intravenous Acetaminophen on Postoperative Hypoxemia After Abdominal Surgery: The FACTOR Randomized Clinical Trial Alparslan Turan, Hani Essber,Wael Saasouh, et al JAMA. 2020;324(4):350-358. doi:10.1001/jama.2020.10009 Abstract Importance 背景 Opioid-induced ventilatory depression and hypoxemia is common, severe, and often unrecognized in postoperative patients. To the extent that nonopioid an...

Research Letter July 14, 2020 Association Between Universal Masking in a Health Care System and SARS-CoV-2 Positivity Among Health Care Workers Xiaowen Wang, Enrico G. Ferro, Guohai Zhou, et al JAMA. Published online July 14, 2020. doi:10.1001/jama.2020.12897 The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has severely affected health care workers (HCWs).1 As a result, hos...

ARTICLES|ONLINE FIRST Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Geneva, Switzerland (SEROCoV-POP): a population-based study Silvia Stringhini, Ania Wisniak, Giovanni Piumatti, et al Lancet Published: June 11, 2020 DOI:https://doi.org/10.1016/S0140-6736(20)31304-0 Summary Background Assessing the burden of COVID-19 on the basis of medically attended case numbers is suboptimal given its reliance on testing strategy, changing case definitions, and...

Original Investigation Caring for the Critically Ill PatientJune 4, 2020 Association of Noninvasive Oxygenation Strategies With All-Cause Mortality in Adults With Acute Hypoxemic Respiratory Failure: A Systematic Review and Meta-analysis Bruno L. Ferreyro, Federico Angriman, Laveena Munshi, et al JAMA. 2020;324(1):57-67. doi:10.1001/jama.2020.9524 Abstract Importance Treatment with noninvasive oxygenation strategie...

Effect of Hydroxychloroquine in Hospitalized Patients with COVID-19: Preliminary results from a multi-centre, randomized, controlled trial ABSTRACT Background 背景 Hydroxychloroquine and chloroquine have been proposed as treatments for coronavirus disease 2019 (COVID-19) on the basis of in vitro activity, uncontrolled data, and small randomized studies. 根据体外活性，非对照研究数据以及小样本随机试验，羟氯喹和氯喹被用于治疗新冠病毒感染(COVID-19)。 Methods 方...

ORIGINAL ARTICLE FREE PREVIEW Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury The STARRT-AKI Investigators for the Canadian Critical Care Trials Group, the Australian and New Zealand Intensive Care Society Clinical Trials Group, the United Kingdom Critical Care Research Group, the Canadian Nephrology Trials Network, and the Irish Critical Care Trials Group N Engl J Med 2020; 383:240-251DOI: 10.1056/NEJMoa2000741 Abstract BACKGR...