Research Efficacy and safety of gastrointestinal bleeding prophylaxis in critically ill patients: systematic review and network meta-analysis Ying Wang, Zhikang Ye, Long Ge, et al BMJ 2020; 368 doi: https://doi.org/10.1136/bmj.l6744 (Published 06 January 2020) Cite this as: BMJ 2020;368:l6744 Abstract Objective 背景 To determine, in critically ill patients, the relative impact of proton pump inhibitors (PPIs), histamine...

Preliminary Communication | December 30, 2019 Effect of Treating Parents Colonized With Staphylococcus aureus on Transmission to Neonates in the Intensive Care Unit: A Randomized Clinical Trial Aaron M. Milstone, Annie Voskertchian, Danielle W. Koontz, et al JAMA. Published online December 30, 2019. doi:https://doi.org/10.1001/jama.2019.20785 Abstract Importance 背景 Staphylococcus aureus is a l...

Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study Summary Background 背景 Sepsis is life-threatening organ dysfunction due to a dysregulated host response to infection. It is considered a major cause of health loss, but data for the global burden of sepsis are limited. As a syndrome caused by underlying infection, sepsis is not part of standard Global Burden of Diseases, Injuries, and Risk Fa...

Research Christmas 2019: Let it Be Q fever—the superstition of avoiding the word “quiet” as a coping mechanism: randomised controlled non-inferiority trial Charlotte R Brookfield, Patrick P J Phillips, Robert J Shorten BMJ 2019; 367: l6446 doi: https://doi.org/10.1136/bmj.l6446 (Published 18 December 2019) Objective 目的 To determine the validity of the superstition that utterance of the word “quiet” in a clinical setting increases workload. 确定在...

Research Christmas 2019: Sweet Little Lies The SSSPIN study—spin in studies of spin: meta-research analysis Lisa Bero, Kellia Chiu, Quinn Grundy BMJ 2019; 367: l6202 doi: https://doi.org/10.1136/bmj.l6202 (Published 18 December 2019) Objectives 目的 To identify and calculate the prevalence of spin in studies of spin. 确定并计算有关倾向性陈述研究中倾向性陈述的比例 Design 试验设计 Meta-research analysis (research on research). meta研究分析(对...

Research Christmas 2019: Shiny Happy People Bend it like Beckham or fix them like Florence—proportional representation of healthcare in New Year honours: an observational study John A Emelifeonwu, James E Hazelwood, Oscar Nolan, et al BMJ 2019;367:l6721 doi: https://doi.org/10.1136/bmj.l6721 (Published 18 December 2019)  Objectives 目的 To compare the proportional representation of healthcare workers in receipt of New Year honours (NYHs) with workers i...

Research Christmas 2019: Sweet Little Lies Gender differences in how scientists present the importance of their research: observational study Marc J Lerchenmueller, Olav Sorenson, Anupam B Jena BMJ 2019; 367: l6573 doi: https://doi.org/10.1136/bmj.l6573 (Published 16 December 2019) Abstract Objectives 目的 Women remain underrepresented on faculties of medicine and the life sciences more broadly. Whether gender differences in self presentation of cli...

ARTICLES| VOLUME 394, ISSUE 10216, P2255-2262, DECEMBER 21, 2019 Public-access defibrillation and neurological outcomes in patients with out-of-hospital cardiac arrest in Japan: a population-based cohort study Takahiro Nakashima, Teruo Noguchi, Yoshio Tahara, et al Lancet 2019; 394: 2255-2262 Background 背景 More than 80% of public-access defibrillation attempts do not result in sustained return of spontaneous circulation in patients who have...

Research Christmas 2019: Chasing Cars Physical activity and weight following car ownership in Beijing, China: quasi-experimental cross sectional study Michael L Anderson, Fangwen Lu, Jun Yang BMJ 2019;367:l6491 doi: https://doi.org/10.1136/bmj.l6491 (Published 18 December 2019) Objective 目的 To determine the implications of car ownership for physical activity and weight in a global city. 确定全球性城市中买车对于体力活动及体重的影响。 Design 试验...

Inhaled amikacin adjunctive to intravenous standard-of-care antibiotics in mechanically ventilated patients with Gram-negative pneumonia (INHALE): a double-blind, randomised, placebo-controlled, phase 3, superiority trial Michael S Niederman, Jeff Alder, Matteo Bassetti, et al Lancet Infect Dis December 19, 2019 DOI:https://doi.org/10.1016/S1473-3099(19)30574-2 Background 背景 Treatment of ventilated pneumonia is often unsuccessful, even when patients are trea...