Research SARS-CoV-2 vaccination and myocarditis or myopericarditis: population based cohort study Anders Husby, Jørgen Vinsløv Hansen, Emil Fosbøl, et al BMJ 2021; 375 doi: https://doi.org/10.1136/bmj-2021-068665 (Published 16 December 2021)Cite this as: BMJ 2021;375:e068665 Abstract Objective To investigate the association between SARS-CoV-2 vaccination and myocarditis or myopericarditis. Design Population based cohort study. Setting D...

ARTICLES|ONLINE FIRST Comparative analysis of the risks of hospitalisation and death associated with SARS-CoV-2 omicron (B.1.1.529) and delta (B.1.617.2) variants in England: a cohort study Tommy Nyberg, Neil M Ferguson, Sophie G Nash, et al Lancet Published:March 16, 2022 DOI:https://doi.org/10.1016/S0140-6736(22)00462-7 Summary Background The omicron variant (B.1.1.529) of SARS-CoV-2 has demonstrated partial vaccine escape and high transmissibility,...

Original Investigation Caring for the Critically Ill PatientMarch 1, 2022 Association of Acute Respiratory Failure in Early Childhood With Long-term Neurocognitive Outcomes R. Scott Watson, Sue R. Beers, Lisa A. Asaro, et al JAMA. 2022;327(9):836-845. doi:10.1001/jama.2022.1480 Key Points Question  Do children with previously normal neurocognitive function who survive an episode of acute respiratory failure requiring intensive care ...

Research Effectiveness of mRNA-1273 against delta, mu, and other emerging variants of SARS-CoV-2: test negative case-control study Katia J Bruxvoort, Lina S Sy, Lei Qian, et al BMJ 2021; 375 doi: https://doi.org/10.1136/bmj-2021-068848 (Published 15 December 2021)Cite this as: BMJ 2021;375:e068848 Abstract Objectives To evaluate the effectiveness of the mRNA-1273 vaccine against SARS-CoV-2 variants and assess its effectiveness against the delta variant...

ONLINE FIRST (FREE ACCESS) LATEST ARTICLES Originals Sepsis hospitalization and risk of subsequent cardiovascular events in adults: a population-based matched cohort studyAngriman F. et al. OPEN ACCESS ~ Veno-venous extracorporeal membrane oxygenation (vv-ECMO) for severe respiratory failure in adult cancer patients: a retrospective multicenter analysisKochanek M. et al. Factors associated with acute mesenteric ischemia among critically ill ventilated patie...

ORIGINAL ARTICLE Population Immunity and Covid-19 Severity with Omicron Variant in South Africa Shabir A. Madhi, Gaurav Kwatra, Jonathan E. Myers, et al N Engl J Med February 23, 2022DOI: 10.1056/NEJMoa2119658 Abstract BACKGROUND The B.1.1.529 (omicron) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified on November 25, 2021, in Gauteng province, South Africa. Data regarding the seroprevalence of SARS-CoV-2 IgG in...

Research Atorvastatin versus placebo in patients with covid-19 in intensive care: randomized controlled trial BMJ 2022; 376 doi: https://doi.org/10.1136/bmj-2021-068407 (Published 07 January 2022)Cite this as: BMJ 2022;376:e06840 Abstract Objective To assess the effect of statin treatment versus placebo on clinical outcomes in patients with covid-19 admitted to the intensive care unit (ICU). Design INSPIRATION/IN...

ONLINE FIRST (FREE ACCESS) LATEST ARTICLES ICM Rapid Practice GuidelinesERC-ESICM guidelines on temperature control after cardiac arrest in adultsSandroni C. et al. OriginalsMental health symptoms in family members of COVID-19 ICU survivors 3 and 12 months after ICU admission: a multicentre prospective cohort studyHeesakkers H. et al.Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in...

ORIGINAL ARTICLEFREE PREVIEW 24-Hour Urinary Sodium and Potassium Excretion and Cardiovascular Risk Yuan Ma, Feng J. He, Qi Sun, et al N Engl J Med 2022; 386:252-263DOI: 10.1056/NEJMoa2109794 Abstract BACKGROUND The relation between sodium intake and cardiovascular disease remains controversial, owing in part to inaccurate assessment of sodium intake. Assessing 24-hour urinary excretion over a period of multiple days is considered to be an accurate metho...

ONLINE FIRST (FREE ACCESS) LATEST ARTICLES OriginalUndocumented migrants in French intensive care units in 2011–2018: retrospective nationwide studyHraiech S. et al. Systematic Review Effect of prone positioning on survival in adult patients receiving venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysisPapazian L. et al. EditorialTowards evidence-based staffing: the promise a...