ARTICLES|ONLINE FIRST Myopericarditis following COVID-19 vaccination and non-COVID-19 vaccination: a systematic review and meta-analysis Ryan Ruiyang Ling, Kollengode Ramanathan, Felicia Liying Tan, et al Lancet Respir Med Published:April 11, 2022 DOI:https://doi.org/10.1016/S2213-2600(22)00059-5 Summary Background Myopericarditis is a rare complication of vaccination. However, there have been increasing reports of myopericarditis following COVID-19 v...

CORRESPONDENCE|ONLINE FIRST Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens Petter Brodin, Moshe Arditi Lancet Gastroenterol Hepatol Published: May 13, 2022 DOI: https://doi.org/10.1016/S2468-1253(22)00166-2 Recently, there have been reports of children with a severe acute form of hepatitis in the UK, Europe, the USA, Israel, and Japan.1 Most patients present with gastrointestinal symptoms and then progress to jaundice and, in ...

Research Letter February 3, 2022 Prevalence and Durability of SARS-CoV-2 Antibodies Among Unvaccinated US Adults by History of COVID-19 Jennifer L. Alejo, Jonathan Mitchell, Amy Chang, et al JAMA. 2022;327(11):1085-1087. doi:10.1001/jama.2022.1393 As of December 28, 2021, approximately 27% of the US population was unvaccinated against SARS-CoV-2,1 yet the prevalence of natural immunity remains unknown. Blood donor studies may have selection bias and lack ...

ARTICLES|ONLINE FIRST Durability of BNT162b2 vaccine against hospital and emergency department admissions due to the omicron and delta variants in a large health system in the USA: a test-negative case–control study Sara Y Tartof, Jeff M Slezak, Laura Puzniak, et al Lancet Respir Med Published:April 22, 2022 DOI:https://doi.org/10.1016/S2213-2600(22)00101-1 Summary Background The duration of protection against the omicron (B.1.1.529) variant for ...

ARTICLES| VOLUME 10, ISSUE 5, P447-458, MAY 01, 2022 Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis Davies Adeloye, Peige Song, Yajie Zhu, et al Lancet Respir Med 2022; 10: 447-458 Summary Background Chronic obstructive pulmonary disease (COPD) is an increasingly important cause of morbidity, disability, and mortality world...

Research Global, regional, and national burden of diseases and injuries for adults 70 years and older: systematic analysis for the Global Burden of Disease 2019 Study BMJ 2022;376:e068208 doi: https://doi.org/10.1136/bmj-2021-068208 (Published 10 March 2022) Abstract Objectives To use data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) to estimate mortality and disability trends for the population aged ≥70 and eval...

Research Benefits and harms of direct oral anticoagulation and low molecular weight heparin for thromboprophylaxis in patients undergoing non-cardiac surgery: systematic review and network meta-analysis of randomised trials BMJ 2022;376:e066785  doi: https://doi.org/10.1136/bmj-2021-066785 (Published 09 March 2022) Abstract Objective To systematically compare the effect of direct oral anticoagulants and low molecular weight heparin for thromboprophylax...

Original Investigation April 5, 2022 Effect of Different Corticosteroid Dosing Regimens on Clinical Outcomes in Boys With Duchenne Muscular Dystrophy: A Randomized Clinical Trial Michela Guglieri, Kate Bushby, Michael P. McDermott, et al JAMA. 2022;327(15):1456-1468. doi:10.1001/jama.2022.4315 Key Points Question  What is the difference in clinical outcomes among 3 corticosteroid regimens (0.75 mg/kg of daily prednisone, 0.90 mg/kg of daily d...

Research Public health impact of covid-19 vaccines in the US: observational study Amitabh Bipin Suthar, Jing Wang, Victoria Seffren, et al BMJ 2022; 377 doi: https://doi.org/10.1136/bmj-2021-069317 (Published 27 April 2022)Cite this as: BMJ 2022;377:e069317 Abstract Objective To evaluate the impact of vaccine scale-up on population level covid-19 mortality and incidence in the United States. Design Observational study. Setting US county...

Research Risks of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19: nationwide self-controlled cases series and matched cohort study Ioannis Katsoularis, Osvaldo Fonseca-Rodríguez, Paddy Farrington, et al BMJ 2022; 377 doi: https://doi.org/10.1136/bmj-2021-069590 (Published 06 April 2022)Cite this as: BMJ 2022;377:e069590 Abstract Objective To quantify the risk of deep vein thrombosis, pulmonary embolism, and bleeding after covid-1...