CORRESPONDENCE|ONLINE FIRST Antibody durability at 1 year after Sputnik V vaccination Lautaro Sanchez, Santiago Oviedo Rouco, Marina Pifano, et al Antibody waning against SARS-CoV-2 over time after vaccination, together with the emergence of new viral variants, pose great challenges for ending the pandemic. To our knowledge, no previous work has assessed the long-term prevalence of anti-SARS-CoV-2 antibodies in individuals vaccinated with Sputnik V (Gam-COVID-Vac...

Preliminary Communication February 10, 2022 Effect of Intra-arterial Alteplase vs Placebo Following Successful Thrombectomy on Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke: The CHOICE Randomized Clinical Trial Arturo Renú, Mónica Millán, Luis San Román, et al JAMA. Published online February 10, 2022. doi:10.1001/jama.2022.1645 Key Points Question  Does the use of adjunct intra-arterial thrombolys...

Research Risk of adverse events after covid-19 in Danish children and adolescents and effectiveness of BNT162b2 in adolescents: cohort study Helene Kildegaard, Lars Christian Lund, Mikkel Højlund, et al BMJ 2022; 377 doi: https://doi.org/10.1136/bmj-2021-068898 (Published 11 April 2022)Cite this as: BMJ 2022;377:e068898 Abstract Objectives To assess the risk of acute and post-acute adverse events after SARS-CoV-2 infection in children and adolescents i...

ARTICLES|ONLINE FIRST Effectiveness of CoronaVac, ChAdOx1 nCoV-19, BNT162b2, and Ad26.COV2.S among individuals with previous SARS-CoV-2 infection in Brazil: a test-negative, case-control study Thiago Cerqueira-Silva, Jason R Andrews, Viviane S Boaventura, et al Lancet Infect Dis Published:March 31, 2022 DOI:https://doi.org/10.1016/S1473-3099(22)00140-2 Summary Background COVID-19 vaccines have proven highly effective among individuals without a previo...

Research App based education programme to reduce salt intake (AppSalt) in schoolchildren and their families in China: parallel, cluster randomised controlled trial Feng J He,  Puhong Zhang, Rong Luo, et al BMJ 2022; 376 doi: https://doi.org/10.1136/bmj-2021-066982 (Published 10 February 2022)Cite this as: BMJ 2022;376:e066982 Abstract Objective To determine whether a smartphone application based education programme can lower salt intake in schoolchildr...

ARTICLES|ONLINE FIRST Risk of SARS-CoV-2 reinfection and COVID-19 hospitalisation in individuals with natural and hybrid immunity: a retrospective, total population cohort study in Sweden Peter Nordström, Marcel Ballin, Anna Nordström Lancet Infect Dis Published:March 31, 2022 DOI:https://doi.org/10.1016/S1473-3099(22)00143-8 Summary Background Real-world evidence supporting vaccination against COVID-19 in individuals who have recovered from a previou...

Research Multifaceted intervention to reduce haemodialysis catheter related bloodstream infections: REDUCCTION stepped wedge, cluster randomised trial Sradha Kotwal, Alan Cass, Sarah Coggan, et al BMJ 2022; 377 doi: https://doi.org/10.1136/bmj-2021-069634 (Published 12 April 2022)Cite this as: BMJ 2022;377:e069634 Abstract Objective To identify whether multifaceted interventions, or care bundles, reduce catheter related bloodstream infections (CRBSIs) ...

ARTICLES| VOLUME 22, ISSUE 4, P483-495, APRIL 01, 2022 Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single-centre, double-blind, randomised, placebo-controlled phase 2 clinical trials Gang Zeng, Qianhui Wu, Hongxing Pan, et al Lancet Infect Dis 2022; 22: 483-495 Summary Background Large-scale vaccination against COVID-19 is being implement...

ARTICLES| VOLUME 399, ISSUE 10335, P1618-1624, APRIL 23, 2022 Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study Cristina Menni, Ana M Valdes, Lorenzo Polidori, et al Lancet 2022; 399: 1618-1624 Summary Background The SARS-CoV-2 variant of concern, omicron, appears to be less se...

ARTICLES|ONLINE FIRST Combining baloxavir marboxil with standard-of-care neuraminidase inhibitor in patients hospitalised with severe influenza (FLAGSTONE): a randomised, parallel-group, double-blind, placebo-controlled, superiority trial Deepali Kumar, Michael G Ison, Jean-Paul Mira, et al Lancet Infect Dis Published:January 24, 2022 DOI:https://doi.org/10.1016/S1473-3099(21)00469-2 Summary Background Neuraminidase inhibitors (NAIs) are considered th...